There has been a growing interest in research concerning memory modification technologies (MMTs) in recent years. Neuroscientists and psychologists are beginning to explore the prospect of controllable and intentional modification of human memory. One of the technologies with the greatest potential to this end is optogenetics—an invasive neuromodulation technique involving the use of light to control the activity of individual brain cells. It has recently shown the potential to modify specific long-term memories in animal models in ways not yet possible (...) with other MMTs. As the therapeutic potential of optogenetics has already prompted approval of the first human trials, it is especially important and timely to consider the opportunities and dangers this technology may entail. In this article, we focus on possible consequences of optogenetics as an MMT by analyzing fundamental threats potentially associated with memory modifications: the potential disruption of personality and authenticity. (shrink)

There has been a growing interest in research concerning memory modification technologies (MMTs) in recent years. Neuroscientists and psychologists are beginning to explore the prospect of controllable and intentional modification of human memory. One of the technologies with the greatest potential to this end is optogenetics—an invasive neuromodulation technique involving the use of light to control the activity of individual brain cells. It has recently shown the potential to modify specific long-term memories in animal models in ways not yet possible (...) with other MMTs. As the therapeutic potential of optogenetics has already prompted approval of the first human trials, it is especially important and timely to consider the opportunities and dangers this technology may entail. In this article, we focus on possible consequences of optogenetics as an MMT by analyzing fundamental threats potentially associated with memory modifications: the potential disruption of personality and authenticity. (shrink)

Optogenetics is an invasive neuromodulation technology involving the use of light to control the activity of individual neurons. Even though optogenetics is a relatively new neuromodulation tool whose various implications have not yet been scrutinized, it has already been approved for its first clinical trials in humans. As optogenetics is being intensively investigated in animal models with the aim of developing novel brain stimulation treatments for various neurological and psychiatric disorders, it appears crucial to consider both the opportunities and dangers (...) such therapies may offer. In this review, we focus on the memory-modifying potential of optogenetics, investigating what it is capable of and how it differs from other memory modification technologies. We then outline the safety challenges that need to be addressed before optogenetics can be used in humans. Finally, we re-examine crucial neuroethical concerns expressed in regard to other MMTs in the light of optogenetics and address those that appear to be unique to the memory-modifying potential of optogenetic technology. (shrink)

The aims of this paper are to: (1) identify the best framework for comprehending multidimensional impact of deep brain stimulation on the self; (2) identify weaknesses of this framework; (3) propose refinements to it; (4) in pursuing (3), show why and how this framework should be extended with additional moral aspects and demonstrate their interrelations; (5) define how moral aspects relate to the framework; (6) show the potential consequences of including moral aspects on evaluating DBS’s impact on patients’ selves. Regarding (...) (1), I argue that the pattern theory of self can be regarded as such a framework. In realizing (2) and (3), I indicate that most relevant issues concerning PTS that require resolutions are ontological issues, including the persistence question, the “specificity problem”, and finding lacking relevant aspects of the self. In realizing (4), I identify aspects of the self not included in PTS which are desperately needed to investigate the full range of potentially relevant DBS-induced changes—authenticity, autonomy, and responsibility, and conclude that how we define authenticity will have implications for our concept of autonomy, which in turn will determine how we think about responsibility. Concerning (5), I discuss a complex relation between moral aspects and PTS—on one hand, they serve as the lens through which a particular self-pattern can be evaluated; on the other, they are, themselves, products of dynamical interactions of various self-aspects. Finally, I discuss (6), demonstrating novel way of understanding the effects of DBS on patients’ selves. (shrink)

Memory modification technologies (MMTs)—interventions within the memory affecting its functions and contents in specific ways—raise great therapeutic hopes but also great fears. Ethicists have expressed concerns that developing and using MMTs may endanger the very fabric of who we are—our personal identity. This threat has been mainly considered in relation to two interrelated concerns: truthfulness and narrative self‐constitution. In this article, we propose that although this perspective brings up important matters concerning the potential aftermaths of MMT utilization, it fails to (...) tell the whole story. We suggest that capturing more tangible potential consequences of MMT use, namely, its psychological ramifications is crucial both in ethical considerations and in making decisions regarding the permissibility of such interventions. To this end, we first examine what current MMTs are capable of and what are the prospects of emerging MMTs. Subsequently, we outline the relationship between memory and personal identity; specifically, we indicate that concepts of self‐defining memories and narrative identity are crucial to considering how MMTs may influence one's psychological functioning. On this basis, we analyze potential consequences of narrative disruption that may be the result of the use of MMTs; more precisely, we consider its potential effects on mental health, well‐being, and personal agency, and outline the ethical dilemmas that decision‐makers face in this context. We conclude by considering the broader cultural context that may have influence on policymaking regarding permissibility of memory modification interventions. (shrink)

For nearly two decades, ethicists have expressed concerns that the further development and use of memory modification technologies (MMTs)—techniques allowing to intentionally and selectively alter memories—may threaten the very foundations of who we are, our personal identity, and thus pose a threat to our well-being, or even undermine our “humaneness.” This paper examines the potential ramifications of memory-modifying interventions such as changing the valence of targeted memories and selective deactivation of a particular memory as these interventions appear to be at (...) the same time potentially both most promising clinically as well as menacing to identity. However, unlike previous works discussing the potential consequences of MMTs, this article analyzes them in the context of the narrative relational approach to personal identity and potential issues related to autonomy. I argue that such a perspective brings to light the ethical aspects and moral issues arising from the use of MMTs that have been hidden from previously adopted approaches. In particular, this perspective demonstrates how important the social context in which an individual lives is for the ethical evaluation of a given memory-modifying intervention. I conclude by suggesting that undertaking memory modifications without taking into account the social dimension of a person’s life creates the risk that she will not be able to meet one of the basic human needs—the autonomous construction and maintenance of personal identity. Based on this conclusion, I offer some reflections on the permissibility and advisability of MMTs and what these considerations suggest for the future. (shrink)

Deep Brain Stimulation (DBS) is an invasive therapeutic method involving the implantation of electrodes and the electrical stimulation of specific areas of the brain to modulate their activity. DBS brings therapeutic benefits, but can also have adverse side effects. Recently, neuroethicists have recognized that DBS poses a threat to the very fabric of human existence, namely, to the selves of patients. This article provides a review of the neuroethical literature examining this issue, and identifies the crucial dimensions related to the (...) self which DBS may endanger—personal identity, authenticity, and autonomy. The most influential theories accounting for these dimensions are analyzed herein, and it is argued that most of these theories require further refinement. This paper also demonstrates the interrelation between personal identity, authenticity, and autonomy, and concludes that one can only fully understand the impact of DBS on the self when all of these factors are taken into account. (shrink)

Schönau et al. (2021) identified four dimensions of agency (authenticity, privacy, self–trust, and responsibility) that may be influenced by the use of neurotechnologies, such as deep brain stimulation (DBS) or brain–computer–interfaces (BCI). The Agency Map they proposed depicts the role of each dimension, and indicates how they may interact. The authors emphasize that a strength of their approach is that it allows to capture the agency dimensions that were previously seen as disconnected and independent as intricately interwoven parts of the (...) person’s experience. This intended unification may help to understand personal agency more fully in various contexts important in neuroethical considerations. However, what is missing in Schönau et al.’s analysis is the mechanism—the very link— by which these various dimensions can come together. As Zawadzki (2020) points out discussing his account of the self (PTS–moral aspects)—which also includes the agency dimensions indicated by Schönau et al. (both authenticity, and responsibility, but also autonomy)—what is crucial in order to unify these various dimensions is narrative. (shrink)

Creations of many contemporary artists indicate the emergence of technoculture. Although artistic manifestations of technoculture may appear to be a provocation, they encourage fundamental ontological questions, such as whether a person has unchanging nature; what was and is our relationship to the Other, and what it should be; to what extent can body and mind be altered before they stop being “human”; what is the future of our species. To properly understand the works of technoculture artists, it appears necessary to (...) have a thorough grasp post- and transhumanism as their key sources of inspiration. As a result, the developed tools will be employed to indicate which aspects of technoculture are a manifestation of post- and transhumanist ideas. This analysis is based primarily on the works of Stelarc and Orlan – two widely commented artists of technoculture. (shrink)

The paper begins with a characterization of thought experiments, followed by a general outline of contemporary debates in the field. The discussion reveals that the most significant controversy involved is the dispute over the epistemic status of thought experiments between empiricists, Platonists, and the proponents of mental models. After a critical analysis of these approaches, a new theoretical framework proposed by Paul Bartha is introduced. It is suggested that Bartha’s approach, which appeals to a theory of analogy, offers new insights (...) into the structure of thought experiments. The paper concludes with general remarks on the state of the art in the field. (shrink)

This article focuses on justified responses to “immoral” behavior and crimes committed by patients undergoing neuromodulation therapies. Such patients could be held morally responsible in the basic desert sense—the one that serves as a justification of severe practices such as backward‐looking moral outrage, condemnation, and legal punishment—as long as they possess certain compatibilist capabilities that have traditionally served as the quintessence of free will, that is, reasons‐responsiveness; attributability; answerability; the abilities to act in accordance with moral reasons, second‐order volitions, or (...) Deep Self. Recently leading compatibilist neuroethicists added the condition of not feeling alienated from desires motivating a person's action. This article argues against such attempts to determine conditions under which patients undergoing neuromodulation should be subject to negative reactive attitudes and legal punishment. Compatibilism should not be used to justify basic desert moral responsibility and legal punishment. Instead, a new way of thinking about the function of moral responsibility attribution is proposed for patients with neuromodulation. Their compatibilist capabilities should serve as important indicators for determining appropriate, forward‐looking courses of action, such as quarantining and restorative treatment, to ensure the public safety and well‐being of the patients. (shrink)

This article introduces a special issue on mechanisms in language evolution research. It describes processes relevant for the emergence of protolanguage and the transition thereof to modern language. Protolanguage is one of the key terms in the field of language evolution, used to designate a hypothesised intermediate stage in the emergence of language present in extinct hominins: qualitatively different from non-human primate communication in possessing some, but not all, of the features that characterise modern language. Much debate in language evolution (...) focuses on the exact delineation of these features, as well as the means whereby the transitions occurred: first from non-human primate communication systems to protolanguage, and then from protolanguage to modern language. In what follows, we first propose a comprehensive typology of protolanguage debates, taking into account the postulated structural organisation of protolanguage, its functions, and its communicative modality. This makes it possible to show how a specific focus on mechanisms and processes deemed relevant for the emergence of these features allows us to assess the explanatory scope of the existing theories of protolanguage. (shrink)

The integration of embodied and computational approaches to cognition requires that non-neural body parts be described as parts of a computing system, which realizes cognitive processing. In this paper, based on research about morphological computations and the ecology of vision, I argue that nonneural body parts could be described as parts of a computational system, but they do not realize computation autonomously, only in connection with some kind of—even in the simplest form—central control system. Finally, I integrate the proposal defended (...) in the paper with the contemporary mechanistic approach to wide computation. (shrink)

In this paper, we defend a novel, multidimensional account of representational unification, which we distinguish from integration. The dimensions of unity are simplicity, generality and scope, non-monstrosity, and systematization. In our account, unification is a graded property. The account is used to investigate the issue of how research traditions contribute to representational unification, focusing on embodied cognition in cognitive science. Embodied cognition contributes to unification even if it fails to offer a grand unification of cognitive science. The study of this (...) failure shows that unification, contrary to what defenders of mechanistic explanation claim, is an important mechanistic virtue of research traditions. (shrink)

In this article, I show the role that the philosopher of cognitive science can cur-rently play in cognitive science research. I argue for the important, and not yet considered, role of the philosophy of cognitive science in cognitive science, that is, the importance of cooperation between philosophers of science with cogni-tive scientists in investigating the research methods and theoretical assump-tions of cognitive science. At the beginning of the paper I point out, how the philosopher of science, here, the philosopher of (...) cognitive science, can participate in interdisciplinary research. I am opting of the cooperation in investigating the so-called reflective problems. Then, I discuss four examples of issues important for the cognitive science, in which the competences possessed by the philosopher are useful. At the ending I point out wider landscape of possible cooperation of philosophers with cognitive scientists. (shrink)

In this paper I briefly discuss principles of “independent ethics” formulated and popularized by the Polish philosopher Tadeusz Kotarbiński. I focus on the notion of “conscience” which seems to play a fundamental role in this moral theory.

In the article, I propose that the body phantom is a phenomenal and functional model of one’s own body. This model has two aspects. On the one hand, it functions as a tacit sensory representation of the body that is at the same time related to the motor aspects of body functioning. On the other hand, it also has a phenomenal aspect as it constitutes the content of conscious bodily experience. This sort of tacit, functional and sensory model is related (...) to the spatial parameters of the physical body. In the article, I postulate that this functional model or map is of crucial importance to the felt ownership parameters of the body (de Vignemont 2007), which are themselves considered as constituting the phenomenal aspect of the aforementioned model. (shrink)

One of the leading and central figures in research on delusions, Max Coltheart, presents and summarises his heretofore work in a short text. Miyazono and Bortolotti present an interesting argument aimed at the charges against the doxastic concept of delusions. Adams, Brown and Friston showcase a predictive-Bayesian concept of delusions. Young criticizes the current changes in the two-factor account of delusions and argues that the role of experience should not be dismissed within it. Kapusta presents an interesting, phenomenological approach to (...) delusions, rooted in the classic works of Karl Jaspers. In the last article, Carruthers takes a look at delusions from a different perspective. He uses them in order to show the weakness of the sense of agency concept as proposed by Wegner. The issue also contains an interview with Jakob Hohwy. In Hohwy’s still-recent book, we can find an interesting, predictive approach to delusions. Hohwy points towards the unobvious connections between delusions and illusions. (shrink)

The body is a highly complex, coordinated system engaged in coping with many environmental problems. It can be considered as some sort of opportunity or obstacle, with which internal processing must deal. Internal processing must take into account the possibilities and limitations of the particular body. In other words, even if the body is not involved in the realization of some cognitive explicit task, it is not a neutral factor of our understanding of why a system solves a task in (...) one way or another. Therefore, when conducting research on embodiment and the body’s cognitive system we should not neglect internal, cognitive processing. I appeal to Goldman’s research on embodied cognition to sketch the broader framework for internal processing in embodied cognition. I believe that even if we don’t accept Goldman’s approach as the viable proposal for embodied cognition in general, it’s a quite natural starting point for our analysis. Goldman (2012; 2014, and with de Vignemont 2009) argue for the essential role of the bodily formats or bodily codes (respectively: B-formats and B-codes) in embodied cognition. B-codes are here described as the processing of regions or sub-regions of the central nervous system. They are primarily employed for body control or monitoring, and reused for cognitive tasks. Beyond doubt, this conception provides an excellent starting point for analyzing the internal (mostly neural) processing in cases of embodied cognition. At the end of this paper, I will argue that the embodiment of cognition needs a conceptual twist. Following Keijzer’s (2015) interest in the evolution of the nervous system, and the minimal forms of cognition, I argue that in investigating embodied cognition, we should investigate the role played by cognitive processing for specific kinds of organisms, meaning organisms with a body of a particular morphology (size, shape, kinds, and distribution of sensors and effectors). Doing that, I refer to some conceptual and empirical considerations. I will also try to show that research on embodied cognition is still not sufficiently anchored in evolutionary and comparative studies on cognition, nor on the nervous system and body morphology. Bigger reliance on these kinds of studies, will make it make possible to gain a deeper understanding of internal processing in embodied cognition. (shrink)

One of the most common questions in today’s cognitive studies is the one regarding embodied cognition. The answer to this question draws our attention to many factors, including bodily actions, which also work to embody cognition. With this in mind, enactivism is included in discussions of embodiment.

This paper is a loose commentary on Marcinów’s book (2017). The commentary is focused on the objects of psychopathological investigations and the role of psychology / psychiatry tension in the process of singling out, tracking, and describing them. As a consequence, there are limitations of collaborative and integrative efforts between psychologists and psychiatrists where questions of psychopathology are concerned.

The de nition of qualia — a contribution to logical philosophy In my article, I propose an abstract de nition of a quale, which (generally speaking) identi es qualia with sets belonging to certain relational structures. I maintain that my de nition, by not taking advantage of psychological terms, makes the notion of a quale more understandable and the existence of qualia themselves less disputable than is commonly supposed. In addition, I brie y discuss the traditional concept of a quale.

We discuss recent progress in the development of cognitive ontologies and summarize three challenges in the coordinated development and application of these resources. Challenge 1 is to adopt a standardized definition for cognitive processes. We describe three possibilities and recommend one that is consistent with the standard view in cognitive and biomedical sciences. Challenge 2 is harmonization. Gaps and conflicts in representation must be resolved so that these resources can be combined for mark-up and interpretation of multi-modal data. Finally, Challenge (...) 3 is to test the utility of these resources for large-scale annotation of data, search and query, and knowledge discovery and integration. As term definitions are tested and revised, harmonization should enable coordinated updates across ontologies. However, the true test of these definitions will be in their community-wide adoption which will test whether they support valid inferences about psychological and neuroscientific data. (shrink)

Całość rozpoczyna teoretyczny rozdział matematyczno-statystyczny. Jego istota i charakter jest odmienny, od pozostałych dziewięciu rozdziałów praktyczno-specjalistycznych. Prezentuje on aparat matematyczno-statystyczny niezbędny do zrozumienia treści kolejnych kierunkowych już rozdziałów monografii. Treści merytoryczne tego rozdziału nie są zaprezentowane w formie systematycznego wykładu, czy prezentacji, ale przedstawiają jedynie sygnalnie i syntetycznie pojęcia, definicje, twierdzenia oraz zasady i metody, które stanowią fundament ich zastosowań w naukach ekonomicznych, finansach oraz informatyce. Rozdziały: od drugiego do dziesiątego są kierunkowymi rozdziałami specjalistycznymi i prezentują różne kierunki praktycznych zastosowań (...) metod matematycznych i statystycznych, czyli ilościowych. Rozdziały: drugi i trzeci dotyczą zarządzania finansami. Przy czym pierwszy z nich dotyczy naliczania odsetek w banku od dyspozytorów kredytów i obligacji. Kolejny zaś traktuje o metodach oceny ekonomicznej efektywności projektów inwestycyjnych i produkcyjnych oraz zawiera analizę wrażliwości wybranych wskaźników finansowych na zmiany czynników je tworzących. Rozdział czwarty prezentuje podstawowe informacje i zasady korzystania z arkusza kalkulacyjnego na przykładzie programu MS Excel wraz z omówieniem wybranych funkcji finansowych. W rozdziale piątym omówione są wybrane narzędzia wspomagające przetwarzanie danych informacji, jakimi są systemy SAS wykorzystywane przede wszystkim w interakcjach gospodarczych oraz w procesie dydaktycznym na uczelniach wyższych. Modele zachowań konsumenta, idea aproksymacji oraz wybrane mikroekonomiczne funkcje popytu zostały – wraz z przykładami – omówione w rozdziale szóstym. W rozdziale siódmym czytelnik znajdzie opis działań podejmowanych przez firmę w celu optymalizacji jej finansowego i gospodarczego funkcjonowania w okresie niepewności rynkowej na przykładzie pandemii COVID 19 i konkretnego przdsiębiorstwa. Dwa kolejne rozdziały: ósmy i dziewiąty są ze sobą ściśle zintegrowane. Oba one dotyczą niedookreślonych układów równań liniowych. Pierwszy z nich – o charakterze teoretycznym – poświęcony jest rozważaniom dotyczącym wykorzystywaniu rachunku macierzowego do rozwiązywania niedookreślonych układów równań liniowych. Kolejny zaś przedstawia praktyczne zastosowanie teoretycznych kwestii rozdziału poprzedniego do określenia wyceny wartości rynkowej nieruchomości. Monografię kończy rozdział dziesiąty dotyczący wybranych narzędzi wspierających proces sprzedaży usług finansowych wraz z prezentacją prognoz służących zminimalizowaniu ryzyka i błędów w procesie planowania sprzedaży w organizacji. W większości rozdziałów zawarte są rozwiązane przykładowo zadania z wyczerpującym komentarzem objaśniającym. Niniejsza monografia składa się z dziesięciu rozdziałów, jednak – zdaniem autorów – tematyka zastosowania metod ilościowych nie została w niej wyczerpana. Toteż planowana jest kolejna część tej publikacji zawierająca kontynuację podjętego i aktualnie rozpoczętego tematu. (shrink)

Open Peer Commentary on P. Zawadzki and A. K. Adamczyk's target article in AJOB Neuroscience on the potential of optogenetics for memory modification. I argue for a radically pluralistic understanding of the notion of authenticity, and highlight the need to further clarify the specific nature of the authors' concern about authenticity, as well as its policy implications.