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  1. Mitochondrial Replacement Techniques, the Non-Identity Problem, and Genetic Parenthood.William Simkulet - 2021 - Asian Bioethics Review 13 (3):317-334.
    Mitochondrial replacement techniques are designed to allow couples to have children without passing on mitochondrial diseases. Recently, Giulia Cavaliere and César Palacios-González argued that prospective parents have the right to use MRTs to pursue genetic relatedness, such that some same-sex couples and/or polygamous triads could use the process to impart genetic relatedness between a child and more of its caregivers. Although MRTs carry medical risks, Cavaliere and Palacios-González contend that because MRTs are identity-affecting, they do not cause harm to an (...)
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  • Should mitochondrial replacement therapy be funded by the National Health Service?Sophie Rhys-Evans - 2021 - Journal of Medical Ethics 47 (3):194-198.
    A clinical trial on mitochondrial replacement therapy is currently being conducted and if this technique proves effective, National Health Service England will fund MRT through the highly specialised services funding stream. This paper considers whether MRT should be publicly funded by the NHS. Given the current financial pressure the NHS is experiencing, a comprehensive discussion is essential. There is yet to be a thorough discussion on MRT funding, perhaps because this is a small-scale issue and presumed to be covered by (...)
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  • Does egg donation for mitochondrial replacement techniques generate parental responsibilities?César Palacios-González - 2018 - Journal of Medical Ethics 44 (12):817-822.
    Children created through mitochondrial replacement techniques (MRTs) are commonly presented as possessing 50% of their mother’s nuclear DNA, 50% of their father’s nuclear DNA and the mitochondrial DNA of an egg donor. This lab-engineered genetic composition has prompted two questions: Do children who are the product of an MRT procedure have threegeneticparents? And, do MRT egg donors have parental responsibilities for the children created? In this paper, I address the second question and in doing so I also address the first (...)
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  • Mitochondrial Replacement Therapy and Identity: A Comment on an Exchange Between Inmaculada de Melo-Martin and John Harris.Søren Holm - 2018 - Cambridge Quarterly of Healthcare Ethics 27 (3):487-491.
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  • Lesbian motherhood and mitochondrial replacement techniques: reproductive freedom and genetic kinship.Giulia Cavaliere & César Palacios-González - 2018 - Journal of Medical Ethics 44 (12):835-842.
    In this paper, we argue that lesbian couples who wish to have children who are genetically related to both of them should be allowed access to mitochondrial replacement techniques. First, we provide a brief explanation of mitochondrial diseases and MRTs. We then present the reasons why MRTs are not, by nature, therapeutic. The upshot of the view that MRTs are non-therapeutic techniques is that their therapeutic potential cannot be invoked for restricting their use only to those cases where a mitochondrial (...)
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