In the age of digitization, the world seems to be reducible to a digital computer. However, mathematically, modern quantum field theories do not only depend on discrete, but also continuous concepts. Ancient debates in natural philosophy on atomism versus the continuum are deeply involved in modern research on digital and computational physics. This example underlines that modern physics, in the tradition of Newton’s Principia Mathematica Philosophiae Naturalis, is a further development of natural philosophy with the rigorous methods of mathematics, measuring, (...) and computing. We consider fundamental concepts of natural philosophy with mathematical and computational methods and ask for their ontological and epistemic status. The following article refers to the author’s book, “The Digital and the Real World. Computational Foundations of Mathematics, Science, Technology, and Philosophy.”. (shrink)