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  1. When imprecision is a good thing, or how imprecise concepts facilitate integration in biology.Celso Neto - 2020 - Biology and Philosophy 35 (6):1-21.
    Contrary to the common-sense view and positivist aspirations, scientific concepts are often imprecise. Many of these concepts are ambiguous, vague, or have an under-specified meaning. In this paper, I discuss how imprecise concepts promote integration in biology and thus benefit science. Previous discussions of this issue focus on the concepts of molecular gene and evolutionary novelty. The concept of molecular gene helps biologists integrate explanatory practices, while the notion of evolutionary novelty helps them integrate research questions into an interdisciplinary problem (...)
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  • Avoiding the potentiality trap: thinking about the moral status of synthetic embryos.Monika Piotrowska - 2019 - Monash Bioethics Review 38 (2):166-180.
    Research ethics committees must sometimes deliberate about objects that do not fit nicely into any existing category. This is currently the case with the “gastruloid,” which is a self-assembling blob of cells that resembles a human embryo. The resemblance makes it tempting to group it with other members of that kind, and thus to ask whether gastruloids really are embryos. But fitting an ambiguous object into an existing category with well-worn pathways in research ethics, like the embryo, is only a (...)
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  • Cancer Clones Revised.Lucie Laplane - forthcoming - Biological Theory:1-14.
    Cancers are hard to treat, and this is largely because cancer cells evolve and diversify through space and time, in patients. The study of clonal evolution relies on the study of cancer cell lineages, and the cutting of these lineages into clones, each clone representing cancer cells with distinctive properties relevant to cancer development and treatment. This notion of clone implies a (set of) simplification(s) that misrepresents the reality. The simplification has been useful and productive, but I argue that maintaining (...)
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  • Commentary on ‘How causal are microbiomes?’.Melinda Bonnie Fagan - 2019 - Biology and Philosophy 34 (6):58.
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  • Let’s Talk About Sex…Cell Lineages.Kate MacCord - forthcoming - Biological Theory:1-14.
    Sex is fundamental to many organisms. It is through sexual reproduction that humans, and many metazoans (multicellular eukaryotes in the animal kingdom), propagate our species. For more than 150 years, sexual reproduction within metazoans has been understood to rely on the existence of a discrete category of cells (germ cells) that are usually considered uniquely separate from all other cells in the body (somatic cells), and which form a cell lineage (germline) that is sequestered from all somatic cell lineages. The (...)
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  • Masking, extrinsicness, and the nature of dispositions: the role of niche signals in muscle stem cells.Javier Suárez - 2023 - European Journal for Philosophy of Science 13 (2):1-29.
    I investigate the intrinsic/extrinsic nature of stemness in muscle stem cells (MSC) by relying on recent research on quiescence, with the aim of shedding light on the nature of dispositions and deriving some consequences about stem cells. First, I argue why the study of quiescence is the best available way to establish any claim about the intrinsicness/extrinsicness of stemness at least is some stem cells. Drawing on that, I argue that MSC’s stem capacities result from the combination of intrinsic cues (...)
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