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  1. Potentials of Experimental Bioethics.Koji Ota - 2021 - Kagaku Tetsugaku 54 (2):3-26.
    There is an emerging experimental trend in bioethics and neuroethics. We briefly review several topics in this trend and discuss how the existing and future studies can have normative implications related to bioethical/neuroethical issues. Particularly, we consider three major ways to draw such implications; (1) contributing to conceptual analysis and philosophical (counter-)evidence, (2) figuring out the unreliability of moral thinking and thereby providing a debunking argument, and (3) estimating the feasibility of ethical norms and policies.
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  • Strong Bipartisan Support for Controlled Psilocybin Use as Treatment or Enhancement in a Representative Sample of US Americans: Need for Caution in Public Policy Persists.Julian D. Sandbrink, Kyle Johnson, Maureen Gill, David B. Yaden, Julian Savulescu, Ivar R. Hannikainen & Brian D. Earp - 2024 - American Journal of Bioethics Neuroscience 15 (2):82-89.
    The psychedelic psilocybin has shown promise both as treatment for psychiatric conditions and as a means of improving well-being in healthy individuals. In some jurisdictions (e.g., Oregon, USA), psilocybin use for both purposes is or will soon be allowed and yet, public attitudes toward this shift are understudied. We asked a nationally representative sample of 795 US Americans to evaluate the moral status of psilocybin use in an appropriately licensed setting for either treatment of a psychiatric condition or well-being enhancement. (...)
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  • The Psychological Process Underlying Attitudes Toward Human-Animal Chimeric Brain Research: An Empirical Investigation.Tetsushi Tanibe, Takumi Watanabe, Mineki Oguchi, Kazuki Iijima & Koji Ota - 2024 - Neuroethics 17 (1):1-19.
    This study adopted an empirical method to investigate lay people’s attitudes toward the bioethical issues of human-animal chimeric brains. The results of online surveys showed that (1) people did not entirely reject chimeric brain research, but showed slightly more negative responses than ordinary animal testing; and that (2) their ethical concerns arose in connection with the perception that chimerism in the brain would humanize the animal. This means that people’s psychology was consistent with the ethical argument that crossing the human-animal (...)
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  • Playing with the “Playing God”.Hossein Dabbagh & E. Andreeva - 2017 - In V. Menuz, J. Roduit, D. Roiz, A. Erler & N. Stepanovan (eds.), Future-Human. Life. neohumanitas. org. pp. 72-78.
    Some philosophers and theologians have argued against the idea of Human Enhancement, saying that human beings should not play God. A closer look, however, might reveal that the question of who is playing Whom is far from being so clear-cut. This chapter will address the idea of human enhancement from the standpoint of theistic theology, arguing that human enhancement and theistic theology may not be so very incompatible, after all.
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  • Bottom Up Ethics - Neuroenhancement in Education and Employment.Hub Zwart, Márton Varju, Vincent Torre, Helge Torgersen, Winnie Toonders, Han Somsen, Ilina Singh, Simone Seyringer, Júlio Santos, Judit Sándor, Núria Saladié, Gema Revuelta, Alexandre Quintanilha, Salvör Nordal, Anna Meijknecht, Sheena Laursen, Nicole Kronberger, Christian Hofmaier, Elisabeth Hildt, Juergen Hampel, Peter Eduard, Rui Cunha, Agnes Allansdottir, George Gaskell & Imre Bard - 2018 - Neuroethics 11 (3):309-322.
    Neuroenhancement involves the use of neurotechnologies to improve cognitive, affective or behavioural functioning, where these are not judged to be clinically impaired. Questions about enhancement have become one of the key topics of neuroethics over the past decade. The current study draws on in-depth public engagement activities in ten European countries giving a bottom-up perspective on the ethics and desirability of enhancement. This informed the design of an online contrastive vignette experiment that was administered to representative samples of 1000 respondents (...)
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  • tDCS for Memory Enhancement: Analysis of the Speculative Aspects of Ethical Issues.Nathalie Voarino, Veljko Dubljević & Eric Racine - 2017 - Frontiers in Human Neuroscience 10.
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  • Recognizing the Diversity of Cognitive Enhancements.Walter Veit, Brian D. Earp, Nadira Faber, Nick Bostrom, Justin Caouette, Adriano Mannino, Lucius Caviola, Anders Sandberg & Julian Savulescu - 2020 - American Journal of Bioethics Neuroscience 11 (4):250-253.
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  • Has the Socio-Political Role of Neuroethics Been Neglected?Walter Veit & Heather Browning - 2022 - American Journal of Bioethics Neuroscience 13 (1):23-25.
    Alongside the rapid global advances in neuroscientific research, neuroethics has been one of the fastest growing sub-fields within bioethics. With this rapid expansion, bioethicists struggle to kee...
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  • Towards a Moral Ecology of Pharmacological Cognitive Enhancement in British Universities.Meghana Kasturi Vagwala, Aude Bicquelet, Gabija Didziokaite, Ross Coomber, Oonagh Corrigan & Ilina Singh - 2017 - Neuroethics 10 (3):389-403.
    Few empirical studies in the UK have examined the complex social patterns and values behind quantitative estimates of the prevalence of pharmacological cognitive enhancement. We conducted a qualitative investigation of the social dynamics and moral attitudes that shape PCE practices among university students in two major metropolitan areas in the UK. Our thematic analysis of eight focus groups suggests a moral ecology that operates within the social infrastructure of the university. We find that PCE resilience among UK university students is (...)
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  • Associations Between the Big Five Personality Traits and the Non-Medical Use of Prescription Drugs for Cognitive Enhancement.Sebastian Sattler & Reinhard Schunck - 2015 - Frontiers in Psychology 6.
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  • What drives public attitudes towards moral bioenhancement and why it matters: an exploratory study.Vojin Rakić, Marko Galjak & Marina Budić - 2021 - BMC Medical Ethics 22 (1):1-14.
    The paper represents an empirical study of public attitudes towards moral bioenhancement. Moral bioenhancement implies the improvement of moral dispositions, i.e. an increase in the moral value of the actions or character of a moral agent. The views of bioethicists and scientists on this topic are present in the ongoing debate, but not the view of the public in general. In order to bridge the gap between the philosophical debate and the view of the public, we have examined attitudes towards (...)
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  • Promoting Fairness in Sport through Performance-enhancing Substances: An Argument for Why Sport Referees Ought to ‘Be on Drugs’.Thomas Søbirk Petersen & Francisco Javier Lopez Frias - 2020 - Sport, Ethics and Philosophy 15 (2):199-207.
    The debate on the use of performance-enhancing substances or methods to improve refereeing is underdeveloped in the sport philosophical literature. This contrast with the attention scholars have de...
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  • Understanding human enhancement technologies through critical phenomenology.Pierre Pariseau-Legault, Dave Holmes & Stuart J. Murray - 2019 - Nursing Philosophy 20 (1):e12229.
    Human enhancement technologies raise serious ethical questions about health practices no longer content simply to treat disease, but which now also propose to “optimize” human beings’ physical, cognitive and psychological abilities. These technologies call for a reassessment of our relationship to health, the human body and the body's organic, identity and social functions. In nursing, such considerations are in their infancy. In this paper, we argue for the relevance of critical phenomenology as a way to better understand the ethical issues (...)
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  • Cognitive Enhancement vs. Plagiarism: a Quantitative Study on the Attitudes of an Italian Sample.Lorenzo Palamenghi & Claudia Bonfiglioli - 2019 - Neuroethics 12 (3):279-292.
    Irrespective of the presence of formal norms, behaviours such as plagiarism, data fabrication and falsification are commonly regarded as unethical and unfair. Almost unanimously, they are considered forms of academic misconduct. Is this the case also for newer behaviours that technology is making possible and are now entering the academic scenario?
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  • How pills undermine skills: Moralization of cognitive enhancement and causal selection.Emilian Mihailov, Blanca Rodríguez López, Florian Cova & Ivar R. Hannikainen - 2021 - Consciousness and Cognition 91 (C):103120.
    Despite the promise to boost human potential and wellbeing, enhancement drugs face recurring ethical scrutiny. The present studies examined attitudes toward cognitive enhancement in order to learn more about these ethical concerns, who has them, and the circumstances in which they arise. Fairness-based concerns underlay opposition to competitive use—even though enhancement drugs were described as legal, accessible and affordable. Moral values also influenced how subsequent rewards were causally explained: Opposition to competitive use reduced the causal contribution of the enhanced winner’s (...)
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  • Introduction: Critiquing technologies of the mind: enhancement, alteration, and anthropotechnology.Darian Meacham - 2017 - Phenomenology and the Cognitive Sciences 16 (1):1-16.
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  • Normality and the Treatment-Enhancement Distinction.Daniel Martín, Jon Rueda, Brian D. Earp & Ivar R. Hannikainen - 2023 - Neuroethics 16 (2):1-14.
    There is little debate regarding the acceptability of providing medical care to restore physical or mental health that has deteriorated below what is considered typical due to disease or disorder (i.e., providing “treatment”—for example, administering psychostimulant medication to sustain attention in the case of attention deficit disorder). When asked whether a healthy individual may undergo the same intervention for the purpose of enhancing their capacities (i.e., “enhancement”—for example, use of a psychostimulant as a “study drug”), people often express greater hesitation. (...)
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  • Neuroethics Inside and Out: A Comparative Survey of Neural Device Industry Representatives and the General Public on Ethical Issues and Principles in Neurotechnology.Katherine E. MacDuffie, Scott Ransom & Eran Klein - forthcoming - American Journal of Bioethics Neuroscience:1-11.
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  • Autonomy and the Limits of Cognitive Enhancement.Jonathan Lewis - 2021 - Bioethics 35 (1):15-22.
    In the debates regarding the ethics of human enhancement, proponents have found it difficult to refute the concern, voiced by certain bioconservatives, that cognitive enhancement violates the autonomy of the enhanced. However, G. Owen Schaefer, Guy Kahane and Julian Savulescu have attempted not only to avoid autonomy-based bioconservative objections, but to argue that cognition-enhancing biomedical interventions can actually enhance autonomy. In response, this paper has two aims: firstly, to explore the limits of their argument; secondly, and more importantly, to develop (...)
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  • The genetic technologies questionnaire: lay judgments about genetic technologies align with ethical theory, are coherent, and predict behaviour.Svenja Küchenhoff, Johannes Doerflinger & Nora Heinzelmann - 2022 - BMC Medical Ethics 23 (54):1-14.
    -/- Policy regulations of ethically controversial genetic technologies should, on the one hand, be based on ethical principles. On the other hand, they should be socially acceptable to ensure implementation. In addition, they should align with ethical theory. Yet to date we lack a reliable and valid scale to measure the relevant ethical judgements in laypeople. We target this lacuna. -/- We developed a scale based on ethical principles to elicit lay judgments: the Genetic Technologies Questionnaire (GTQ). In two pilot (...)
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  • How the Public Engages With Brain Optimization: The Media-mind Relationship.Helene Joffe & Cliodhna O’Connor - 2015 - Science, Technology, and Human Values 40 (5):712-743.
    In the burgeoning debate about neuroscience’s role in contemporary society, the issue of brain optimization, or the application of neuroscientific knowledge and technologies to augment neurocognitive function, has taken center stage. Previous research has characterized media discourse on brain optimization as individualistic in ethos, pressuring individuals to expend calculated effort in cultivating culturally desirable forms of selves and bodies. However, little research has investigated whether the themes that characterize media dialogue are shared by lay populations. This article considers the relationship (...)
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  • Noninvasive Brain Stimulation and Personal Identity: Ethical Considerations.Jonathan Iwry, David B. Yaden & Andrew B. Newberg - 2017 - Frontiers in Human Neuroscience 11.
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  • Toward a Method for Exposing and Elucidating Ethical Issues with Human Cognitive Enhancement Technologies.Bjørn Hofmann - 2017 - Science and Engineering Ethics 23 (2):413-429.
    To develop a method for exposing and elucidating ethical issues with human cognitive enhancement. The intended use of the method is to support and facilitate open and transparent deliberation and decision making with respect to this emerging technology with great potential formative implications for individuals and society. Literature search to identify relevant approaches. Conventional content analysis of the identified papers and methods in order to assess their suitability for assessing HCE according to four selection criteria. Method development. Amendment after pilot (...)
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  • The Multiplicity of Memory Enhancement: Practical and Ethical Implications of the Diverse Neural Substrates Underlying Human Memory Systems.Kieran C. R. Fox, Nicholas S. Fitz & Peter B. Reiner - 2016 - Neuroethics 10 (3):375-388.
    The neural basis of human memory is incredibly complex. We argue that the diversity of neural systems underlying various forms of memory suggests that any discussion of enhancing ‘memory’ per se is too broad, thus obfuscating the biopolitical debate about human enhancement. Memory can be differentiated into at least four major systems with largely dissociable neural substrates. We outline each system, and discuss both the practical and the ethical implications of these diverse neural substrates. In practice, distinct neural bases imply (...)
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  • The is and ought of the Ethics of Neuroenhancement: Mind the Gap.Cynthia Forlini & Wayne Hall - 2015 - Frontiers in Psychology 6.
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  • Context-Dependent Risk & Benefit Sensitivity Mediate Judgments About Cognitive Enhancement.Kiante Fernandez, Roy Hamilton, Laura Cabrera & John Dominic Medaglia - 2022 - American Journal of Bioethics Neuroscience 13 (1):73-77.
    Opinions about cognitive enhancement (CE) are context-dependent. Prior research has demonstrated that factors like peer pressure, the influence of authority figures, competition, moral relevance, familiarity with enhancement devices, expertise, and the domain of CE to be enhanced can influence opinions. The variability and malleability of patient, expert, and public attitudes toward CE is important to describe and predict because these attitudes can influence at-home, clinical, research, and regulatory decisions. If individual preferences vary, they could influence opinions about practices and regulations (...)
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  • Quantitative Anticipatory Ethical Analysis Should Inform Neurotechnology Development.Gidon Felsen & Peter B. Reiner - 2017 - American Journal of Bioethics Neuroscience 8 (2):75-77.
    Effective neuromodulation of the human brain is a central objective of neuroscience, with clear applications for restoring, and even enhancing, neural function. Whether it is a pill that modifies p...
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  • Why is Cognitive Enhancement Deemed Unacceptable? The Role of Fairness, Deservingness, and Hollow Achievements.Nadira S. Faber, Julian Savulescu & Thomas Douglas - 2016 - Frontiers in Psychology 7.
    We ask why pharmacological cognitive enhancement (PCE) is generally deemed morally unacceptable by lay people. Our approach to this question has two core elements. First, we employ an interdisciplinary perspective, using philosophical rationales as base for generating psychological models. Second, by testing these models we investigate how different normative judgments on PCE are related to each other. Based on an analysis of the relevant philosophical literature, we derive two psychological models that can potentially explain the judgment that PCE is unacceptable: (...)
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  • Present and Emerging Ethical Issues with tDCS use: A Summary and Review.Parker Day, Jack Twiddy & Veljko Dubljević - 2022 - Neuroethics 16 (1):1-25.
    Transcranial direct current stimulation (tDCS) is a brain stimulation technique known for its relative safety and minimal invasiveness. tDCS has demonstrated efficacy as a potential treatment for certain neurological disorders, such as Parkinson’s disease, and has been shown to enhance a range of cognitive abilities under certain contexts. As a result, this technique has captured the interest of both the research community and the public at large. However, efforts to gather information about the effects of tDCS on the brain are (...)
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  • Whose Mental Data? Privacy Inequities and Extended Minds.C. Dalrymple-Fraser - 2023 - American Journal of Bioethics Neuroscience 14 (2):104-106.
    People crossing the border into the United States or Canada may find their electronic devices subject to search. Border agents can require travelers to unlock their devices, and then browse through...
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  • Attitudes Toward Cognitive Enhancement: The Role of Metaphor and Context.Erin C. Conrad, Stacey Humphries & Anjan Chatterjee - 2019 - American Journal of Bioethics Neuroscience 10 (1):35-47.
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  • Cognitive biases can affect moral intuitions about cognitive enhancement.Lucius Caviola, Adriano Mannino, Julian Savulescu & Nadira Faber - 2014 - Frontiers in Systems Neuroscience 8.
    Research into cognitive biases that impair human judgment has mostly been applied to the area of economic decision-making. Ethical decision-making has been comparatively neglected. Since ethical decisions often involve very high individual as well as collective stakes, analyzing how cognitive biases affect them can be expected to yield important results. In this theoretical article, we consider the ethical debate about cognitive enhancement and suggest a number of cognitive biases that are likely to affect moral intuitions and judgments about CE: status (...)
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  • The Epistemology of Cognitive Enhancement.J. Adam Carter & Duncan Pritchard - 2016 - Journal of Medicine and Philosophy (2):220-242.
    A common epistemological assumption in contemporary bioethics held b y both proponents and critics of non-traditional forms of cognitive enhancement is that cognitive enhancement aims at the facilitation of the accumulation of human knowledge. This paper does three central things. First, drawing from recent work in epistemology, a rival account of cognitive enhancement, framed in terms of the notion of cognitive achievement rather than knowledge, is proposed. Second, we outline and respond to an axiological objection to our proposal that draws (...)
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  • Reasons for Comfort and Discomfort with Pharmacological Enhancement of Cognitive, Affective, and Social Domains.Laura Y. Cabrera, Nicholas S. Fitz & Peter B. Reiner - 2014 - Neuroethics 8 (2):93-106.
    The debate over the propriety of cognitive enhancement evokes both enthusiasm and worry. To gain further insight into the reasons that people may have for endorsing or eschewing pharmacological enhancement, we used empirical tools to explore public attitudes towards PE of twelve cognitive, affective, and social domains. Participants from Canada and the United States were recruited using Mechanical Turk and were randomly assigned to read one vignette that described an individual who uses a pill to enhance a single domain. After (...)
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  • Empirical Support for the Moral Salience of the Therapy-Enhancement Distinction in the Debate Over Cognitive, Affective and Social Enhancement.Laura Y. Cabrera, Nicholas S. Fitz & Peter B. Reiner - 2014 - Neuroethics 8 (3):243-256.
    The ambiguity regarding whether a given intervention is perceived as enhancement or as therapy might contribute to the angst that the public expresses with respect to endorsement of enhancement. We set out to develop empirical data that explored this. We used Amazon Mechanical Turk to recruit participants from Canada and the United States. Each individual was randomly assigned to read one vignette describing the use of a pill to enhance one of 12 cognitive, affective or social domains. The vignettes described (...)
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  • The Influence of Using Novel Predictive Technologies on Judgments of Stigma, Empathy, and Compassion among Healthcare Professionals.Daniel Z. Buchman, Daphne Imahori, Christopher Lo, Katrina Hui, Caroline Walker, James Shaw & Karen D. Davis - 2024 - American Journal of Bioethics Neuroscience 15 (1):32-45.
    Background Our objective was to evaluate whether the description of a machine learning (ML) app or brain imaging technology to predict the onset of schizophrenia or alcohol use disorder (AUD) influences healthcare professionals’ judgments of stigma, empathy, and compassion.Methods We randomized healthcare professionals (N = 310) to one vignette about a person whose clinician seeks to predict schizophrenia or an AUD, using a ML app, brain imaging, or a psychosocial assessment. Participants used scales to measure their judgments of stigma, empathy, (...)
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  • From ‘Hard’ Neuro-Tools to ‘Soft’ Neuro-Toys? Refocussing the Neuro-Enhancement Debate.Jonna Brenninkmeijer & Hub Zwart - 2016 - Neuroethics 10 (3):337-348.
    Since the 1990’s, the debate concerning the ethical, legal and societal aspects of ‘neuro-enhancement’ has evolved into a massive discourse, both in the public realm and in the academic arena. This ethical debate, however, tends to repeat the same sets of arguments over and over again. Normative disagreements between transhumanists and bioconservatives on invasive or radical brain stimulators, and uncertainties regarding the use and effectivity of nootropic pharmaceuticals dominate the field. Building on the results of an extensive European project on (...)
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  • L’impianto cocleare come potenziatore cognitivo? Una prospettiva neuroetica sulle obiezioni della comunità sorda.Claudia Bonfiglioli & Francesco Pavani - 2020 - Rivista Internazionale di Filosofia e Psicologia 11 (3):283-306.
    Riassunto: L’impianto cocleare è una neuroprotesi che consente un recupero parziale dell’udito nella persona sorda. Nonostante la sua generale efficacia nel contrastare alcuni dei problemi legati alla sordità, il suo utilizzo è stato fortemente osteggiato da quella parte della comunità sorda che vede nella sordità una forma di identità culturale e non una patologia. Questo articolo inquadra in una prospettiva neuroetica le preoccupazioni della comunità sorda – difficilmente comprensibili agli udenti – esaminando le analogie fra il rifiuto dell’IC e il (...)
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  • Cognitive Enhancement: Unanswered Questions About Human Psychology and Social Behavior.Wren Boehlen, Sebastian Sattler & Eric Racine - 2021 - Science and Engineering Ethics 27 (2):1-25.
    Stimulant drugs, transcranial magnetic stimulation, brain-computer interfaces, and even genetic modifications are all discussed as forms of potential cognitive enhancement. Cognitive enhancement can be conceived as a benefit-seeking strategy used by healthy individuals to enhance cognitive abilities such as learning, memory, attention, or vigilance. This phenomenon is hotly debated in the public, professional, and scientific literature. Many of the statements favoring cognitive enhancement (e.g., related to greater productivity and autonomy) or opposing it (e.g., related to health-risks and social expectations) rely (...)
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  • Bottom Up Ethics - Neuroenhancement in Education and Employment.Imre Bard, George Gaskell, Agnes Allansdottir, Rui Vieira da Cunha, Peter Eduard, Juergen Hampel, Elisabeth Hildt, Christian Hofmaier, Nicole Kronberger, Sheena Laursen, Anna Meijknecht, Salvör Nordal, Alexandre Quintanilha, Gema Revuelta, Núria Saladié, Judit Sándor, Júlio Borlido Santos, Simone Seyringer, Ilina Singh, Han Somsen, Winnie Toonders, Helge Torgersen, Vincent Torre, Márton Varju & Hub Zwart - 2018 - Neuroethics 11 (3):309-322.
    Neuroenhancement involves the use of neurotechnologies to improve cognitive, affective or behavioural functioning, where these are not judged to be clinically impaired. Questions about enhancement have become one of the key topics of neuroethics over the past decade. The current study draws on in-depth public engagement activities in ten European countries giving a bottom-up perspective on the ethics and desirability of enhancement. This informed the design of an online contrastive vignette experiment that was administered to representative samples of 1000 respondents (...)
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  • Cognitive Enhancement: Toward a Rational Public Consensus.Eman Ahmed & Kristien Hens - 2020 - American Journal of Bioethics Neuroscience 11 (4):263-265.
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