Kyle Stanford has recently given substance to the problem of unconceived alternatives, which challenges the reliability of inference to the best explanation (IBE) in remote domains of nature. Conjoined with the view that IBE is the central inferential tool at our disposal in investigating these domains, the problem of unconceived alternatives leads to scientific anti-realism. We argue that, at least within the biological community, scientists are now and have long been aware of the dangers of IBE. We re-analyze the nineteenth-century (...) study of inheritance and development (Stanford’s case study) and extend it into the twentieth century, focusing in particular on both classical Mendelian genetics and the studies by Avery et al. on the chemical nature of the hereditary substance. Our extended case studies show the preference of the biological community for a different methodological standard: the vera causa ideal, which requires that purported causes be shown on non-explanatory grounds to exist and be competent to produce their effects. On this basis, we defend a prospective realism about the biological sciences. (shrink)

In this paper, I respond to Sterpetti’s attempt to defend Kyle P. Stanford’s Problem of Unconceived Alternatives and his New Induction over the History of Science from my reductio argument outlined in Mizrahi :59–68, 2016a). I discuss what I take to be the ways in which Sterpetti has misconstrued my argument against Stanford’s NIS, in particular, that it is a reductio, not a dilemma, as Sterpetti erroneously thinks. I argue that antirealists who endorse Stanford’s NIS still face an absurd consequence (...) of this argument, namely, that they should not believe their own brand of scientific antirealism. (shrink)

A prominent type of scientific realism holds that some important parts of our best current scientific theories are at least approximately true. According to such realists, radically distinct alternatives to these theories or theory-parts are unlikely to be approximately true. Thus one might be tempted to argue, as the prominent anti-realist Kyle Stanford recently did, that realists of this kind have little or no reason to encourage scientists to attempt to identify and develop theoretical alternatives that are radically distinct from (...) currently accepted theories in the relevant respects. In other words, it may seem that realists should recommend that scientists be relatively conservative in their theoretical endeavors. This paper aims to show that this argument is mistaken. While realists should indeed be less optimistic of finding radically distinct alternatives to replace current theories, realists also have greater reasons to value the outcomes of such searches. Interestingly, this holds both for successful and failed attempts to identify and develop such alternatives. (shrink)