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  1. Two variants of ‘constrained participation’ in the care of vulnerable adults: A proof-of-concept study.Kristján Kristjánsson & Kristín Thórarinsdóttir - 2024 - Nursing Ethics 31 (1):39-51.
    There has been a radical turn towards ideals of patient autonomy and person-centred care, and away from historically entrenched forms of medical paternalism, in the last 50 years of nursing practice. However, along the way, some shades of grey between the areas of ideal patient participation and of outright patient non-participation have been missed. The current article constitutes an exploratory proof-of-concept study of the real-world traction of a distinction-straddling concept of ‘constrained participation’ and its two sub-concepts of ‘fought-for participation’ and (...)
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  • Regimes of Evidence in Complexity Sciences.Fabrizio Li Vigni - 2021 - Perspectives on Science 29 (1):62-103.
    Since their inception in the 1980s, complexity sciences have been described as a revolutionary new domain of research. By describing some of the practices and assumptions of its representatives, the present article shows that this field is an association of subdisciplines laying on existing disciplinary footholds. The general question guiding us here is: On what basis do complexity scientists consider their inquiry methods and results as valuable? To answer it, I describe five “epistemic argumentative regimes,” namely the ways in which (...)
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  • Multiple Realizability and Biological Modality.Rami Koskinen - 2019 - Philosophy of Science 86 (5):1123-1133.
    Critics of multiple realizability have recently argued that we should concentrate solely on actual here-and-now realizations that are found in nature. The possibility of alternative, but unactualized, realizations is regarded as uninteresting because it is taken to be a question of pure logic or an unverifiable scenario of science fiction. However, in the biological context only a contingent set of realizations is actualized. Drawing on recent work on the theory of neutral biological spaces, the paper shows that we can have (...)
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  • The history and philosophy of taxonomy as an information science.Catherine Kendig & Joeri Witteveen - 2020 - History and Philosophy of the Life Sciences 42 (3):1-9.
    We undeniably live in an information age—as, indeed, did those who lived before us. After all, as the cultural historian Robert Darnton pointed out: ‘every age was an age of information, each in its own way’ (Darnton 2000: 1). Darnton was referring to the news media, but his insight surely also applies to the sciences. The practices of acquiring, storing, labeling, organizing, retrieving, mobilizing, and integrating data about the natural world has always been an enabling aspect of scientific work. Natural (...)
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  • Reengineering Metaphysics: Modularity, Parthood, and Evolvability in Metabolic Engineering.Catherine Kendig & Todd T. Eckdahl - 2017 - Philosophy, Theory, and Practice in Biology 9 (8).
    The premise of biological modularity is an ontological claim that appears to come out of practice. We understand that the biological world is modular because we can manipulate different parts of organisms in ways that would only work if there were discrete parts that were interchangeable. This is the foundation of the BioBrick assembly method widely used in synthetic biology. It is one of a number of methods that allows practitioners to construct and reconstruct biological pathways and devices using DNA (...)
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  • Exploring biological possibility through synthetic biology.Tero Ijäs & Rami Koskinen - 2021 - European Journal for Philosophy of Science 11 (2):1-17.
    This paper analyzes the notion of possibility in biology and demonstrates how synthetic biology can provide understanding on the modal dimension of biological systems. Among modal concepts, biological possibility has received surprisingly little explicit treatment in the philosophy of science. The aim of this paper is to argue for the importance of the notion of biological possibility by showing how it provides both a philosophically and biologically fruitful category as well as introducing a new practically grounded way for its assessment. (...)
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  • Proof of Concept Research.Steve Elliott - 2021 - Philosophy of Science 88 (2):258-280.
    Researchers often pursue proof of concept research, but criteria for evaluating such research remain poorly specified. This article proposes a general framework for proof of concept research that k...
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  • Editors’ Overview: Experiments, Ethics, and New Technologies.Neelke Doorn, Shannon Spruit & Zoë Robaey - 2016 - Science and Engineering Ethics 22 (3):607-611.
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