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  1. Brain, Consciousness and Disorders of Consciousness at the Intersection of Neuroscience and Philosophy.Michele Farisco - 2019 - Dissertation, Uppsala University
    The present dissertation starts from the general claim that neuroscience is not neutral, with regard to theoretical questions like the nature of consciousness, but it needs to be complemented with dedicated conceptual analysis. Specifically, the argument for this thesis is that the combination of empirical and conceptual work is a necessary step for assessing the significant questions raised by the most recent study of the brain. Results emerging from neuroscience are conceptually very relevant in themselves but, notwithstanding its theoretical sophistication, (...)
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  • Conceptual Constructive Models and Abstraction-as-Aggregation.Sim-Hui Tee - forthcoming - Philosophia:1-19.
    Conceptual constructive models are a type of scientific model that can be used to construct or reshape the target phenomenon conceptually. Though it has received scant attention from the philosophers, it raises an intriguing issue of how a conceptual constructive model can construct the target phenomenon in a conceptual way. Proponents of the conception of conceptual constructive models are not being explicit about the application of the constructive force of a model in the target construction. It is far from clear (...)
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  • Biological accuracy in large-scale brain simulations.Edoardo Datteri - 2020 - History and Philosophy of the Life Sciences 42 (1):1-22.
    The advancement of computing technology makes it possible to build extremely accurate digital reconstructions of brain circuits. Are such unprecedented levels of biological accuracy essential for brain simulations to play the roles they are expected to play in neuroscientific research? The main goal of this paper is to clarify this question by distinguishing between various roles played by large-scale simulations in contemporary neuroscience, and by reflecting about what makes a simulation biologically accurate. It is argued that large-scale simulations may play (...)
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  • Large-Scale Brain Simulation and Disorders of Consciousness. Mapping Technical and Conceptual Issues.Michele Farisco, Jeanette H. Kotaleski & Kathinka Evers - 2018 - Frontiers in Psychology 9.
    Modelling and simulations have gained a leading position in contemporary attempts to describe, explain, and quantitatively predict the human brain's operations. Computer models are highly sophisticated tools developed to achieve an integrated knowledge of the brain with the aim of overcoming the actual fragmentation resulting from different neuroscientific approaches. In this paper we investigate plausibility of simulation technologies for emulation of consciousness and the potential clinical impact of large-scale brain simulation on the assessment and care of disorders of consciousness, e.g. (...)
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  • How Metaphysical Commitments Shape the Study of Psychological Mechanisms.Eric Hochstein - forthcoming - Theory & Psychology.
    The study of psychological mechanisms is an interdisciplinary endeavour, requiring insights from many different domains. In this article, I argue that philosophy plays an essential role in this interdisciplinary project, and that effective scientific study of psychological mechanisms requires that working scientists be responsible metaphysicians. This means adopting deliberate metaphysical positions when studying mechanisms that go beyond what is empirically justified regarding the nature of the phenomenon being studied, the conditions of its occurrence, and its boundaries. Such metaphysical commitments are (...)
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  • Replicability or Reproducibility? On the Replication Crisis in Computational Neuroscience and Sharing Only Relevant Detail.Marcin Miłkowski, Witold M. Hensel & Mateusz Hohol - 2018 - Journal of Computational Neuroscience 3 (45):163-172.
    Replicability and reproducibility of computational models has been somewhat understudied by “the replication movement.” In this paper, we draw on methodological studies into the replicability of psychological experiments and on the mechanistic account of explanation to analyze the functions of model replications and model reproductions in computational neuroscience. We contend that model replicability, or independent researchers' ability to obtain the same output using original code and data, and model reproducibility, or independent researchers' ability to recreate a model without original code, (...)
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  • From Computer Metaphor to Computational Modeling: The Evolution of Computationalism.Marcin Miłkowski - 2018 - Minds and Machines 28 (3):515-541.
    In this paper, I argue that computationalism is a progressive research tradition. Its metaphysical assumptions are that nervous systems are computational, and that information processing is necessary for cognition to occur. First, the primary reasons why information processing should explain cognition are reviewed. Then I argue that early formulations of these reasons are outdated. However, by relying on the mechanistic account of physical computation, they can be recast in a compelling way. Next, I contrast two computational models of working memory (...)
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  • Integrating Cognitive (Neuro)Science Using Mechanisms.Marcin Miłkowski - 2016 - Avant: Trends in Interdisciplinary Studies (2):45-67.
    In this paper, an account of theoretical integration in cognitive (neuro)science from the mechanistic perspective is defended. It is argued that mechanistic patterns of integration can be better understood in terms of constraints on representations of mechanisms, not just on the space of possible mechanisms, as previous accounts of integration had it. This way, integration can be analyzed in more detail with the help of constraintsatisfaction account of coherence between scientific representations. In particular, the account has resources to talk of (...)
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  • Situatedness and Embodiment of Computational Systems.Marcin Miłkowski - 2017 - Entropy 19 (4):162.
    In this paper, the role of the environment and physical embodiment of computational systems for explanatory purposes will be analyzed. In particular, the focus will be on cognitive computational systems, understood in terms of mechanisms that manipulate semantic information. It will be argued that the role of the environment has long been appreciated, in particular in the work of Herbert A. Simon, which has inspired the mechanistic view on explanation. From Simon’s perspective, the embodied view on cognition seems natural but (...)
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  • Models and Mechanisms in Network Neuroscience.Carlos Zednik - 2018 - Philosophical Psychology 32 (1):23-51.
    This paper considers the way mathematical and computational models are used in network neuroscience to deliver mechanistic explanations. Two case studies are considered: Recent work on klinotaxis by Caenorhabditis elegans, and a longstanding research effort on the network basis of schizophrenia in humans. These case studies illustrate the various ways in which network, simulation and dynamical models contribute to the aim of representing and understanding network mechanisms in the brain, and thus, of delivering mechanistic explanations. After outlining this mechanistic construal (...)
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  • Computational Cognitive Neuroscience.Carlos Zednik - forthcoming - In Mark Sprevak & Matteo Colombo (eds.), The Routledge Handbook of the Computational Mind. Routledge.
    This chapter provides an overview of the basic research strategies and analytic techniques deployed in computational cognitive neuroscience. On the one hand, “top-down” strategies are used to infer, from formal characterizations of behavior and cognition, the computational properties of underlying neural mechanisms. On the other hand, “bottom-up” research strategies are used to identify neural mechanisms and to reconstruct their computational capacities. Both of these strategies rely on experimental techniques familiar from other branches of neuroscience, including functional magnetic resonance imaging, single-cell (...)
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  • Are More Details Better? On the Norms of Completeness for Mechanistic Explanations.Carl F. Craver & David M. Kaplan - 2020 - British Journal for the Philosophy of Science 71 (1):287-319.
    Completeness is an important but misunderstood norm of explanation. It has recently been argued that mechanistic accounts of scientific explanation are committed to the thesis that models are complete only if they describe everything about a mechanism and, as a corollary, that incomplete models are always improved by adding more details. If so, mechanistic accounts are at odds with the obvious and important role of abstraction in scientific modelling. We respond to this characterization of the mechanist’s views about abstraction and (...)
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  • Abstraction in Ecology: Reductionism and Holism as Complementary Heuristics.Jani Raerinne - 2018 - European Journal for Philosophy of Science 8 (3):395-416.
    In addition to their core explanatory and predictive assumptions, scientific models include simplifying assumptions, which function as idealizations, approximations, and abstractions. There are methods to investigate whether simplifying assumptions bias the results of models, such as robustness analyses. However, the equally important issue – the focus of this paper – has received less attention, namely, what are the methodological and epistemic strengths and limitations associated with different simplifying assumptions. I concentrate on one type of simplifying assumption, the use of mega (...)
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