Recently, there has been a growing interest, both within theoretical biology and the philosophy of biology, in the possibility and desirability of a theory of development. Among the many issues raised within this debate, the questions of the spatial and temporal boundaries of development have received particular attention. In this article, noting that so far the discussion has mostly centered on the processes of morphogenesis and organogenesis, we argue that an important missing element in the equation, namely the development of (...) language and cognition in general, may play an important role in settling the issue of temporal boundaries. After examining the idea that the development of language, cognition, and action are bona fide biological processes, we explore the consequences for a general theory of development of taking them into consideration. (shrink)

Edited by Alessandro Minelli and Thomas Pradeu, Towards a Theory of Development gathers essays by biologists and philosophers, which display a diversity of theoretical perspectives. The discussions not only cover the state of art, but broaden our vision of what development includes and provide pointers for future research. Interestingly, all contributors agree that explanations should not just be gene-centered, and virtually none use design and other engineering metaphors to articulate principles of cellular and organismal organization. I comment in particular on (...) the issue of how to construe the notion of a ‘theory’ and whether developmental biology has or should aspire to have theories, which four of the contributions discuss in detail while taking opposing positions. Beyond construing a theory in terms of its empirical content, my aim is to shift the focus toward the role that theories have for guiding future scientific theorizing and practice. Such a conception of ‘theory’ is particularly important in the context of development, because arriving at a theoretical framework that provides guidance for the discipline of developmental biology as a whole is more plausible than a unified representation of development across all taxa. (shrink)

The aim of this thesis dissertation is to propose a novel position in the debate on scientific realism, modal empiricism, and to show its fruitfulness when it comes to interpreting the cognitive content of scientific theories. Modal empiricism is an empiricist position, according to which the aim of science is to produce empirically adequate theories rather than true theories. However, it suggests adopting a broader comprehension of experience than traditional versions of empiricism, through a commitment to natural modalities. Following modal (...) empiricism, there are possibilities in nature, and constraints on what is possible, and a theory is empirically adequate if it correctly delimits the range of possible experiences. The position rests on a situated and pragmatic conception of natural modalities and of empirical confrontation. We claim that it can do justice to the empirical success of science, while not falling prey to the problem of theory change that undermines scientific realism. We explain how constraints of necessity on phenomena can be known by induction, and how this modal epistemology fits with scientific practice. Finally, we claim that a commitment to natural modalities allows for a rich interpretation of the cognitive content of theories. Modal empiricism could renew some metaphysical debates within a pragmatist framework, by tying them to experience and not being constrained by realist prejudices. -/- L'objet de cette thèse est de proposer une position originale dans le débat sur le réalisme scientifique, l'empirisme modal, et d'en démontrer la fructuosité quand il s'agit de tirer des enseignements du contenu cognitif des théories scientifiques. L'empirisme modal est une position empiriste, suivant laquelle le but de la science n'est pas de produire des théories vraies, mais des théories empiriquement adéquate. Cependant, il propose d'adopter un cadre plus large que les versions traditionnelles d'empirisme pour penser l'expérience, en incorporant un engagement envers les modalités naturelles, ou l'idée qu'il y a du possible dans la nature, et des contraintes sur les possibles. Nos théories sont empiriquement adéquates si elles délimitent correctement l'étendue des expériences possibles. Cette position s'appuie sur une conception située et pragmatique des modalités naturelles et de la confrontation empirique. Nous prétendons qu'elle est à même de rendre justice au succès empirique des sciences, sans pour autant faire face au problème du changement théorique qui mine le réalisme scientifique. Nous expliquons comment les contraintes de nécessité sur les phénomènes peuvent être connues à l'issue d'une induction, et en quoi cette façon de voir s'accorde avec la pratique scientifique. Enfin, nous affirmons qu'un engagement envers les modalités naturelles offre une richesse interprétative à même de renouveler, dans un cadre pragmatiste, plus ouvert que le réalisme, certaines questions métaphysiques tout en les ramenant à l'expérience . (shrink)

This paper aims to clarify the consequences of new scientific and philosophical approaches for the practical-theoretical framework of modern developmental biology. I highlight normal development, and the instructive-permissive distinction, as key parts of this framework which shape how variation is conceptualised and managed. Furthermore, I establish the different dimensions of biological variation: the units, temporality and mode of variation. Using the analytical frame established by this, I interpret a selection of examples as challenges to the instructive-permissive distinction. These examples include (...) the phenomena of developmental plasticity and transdifferentiation, the role of the microbiome in development, and new methodological approaches to standardisation and the assessment of causes. Furthermore, I argue that investigations into organismal development should investigate the effects of a wider range of kinds of variation including variation in the units, modes and temporalities of development. I close by examining various possible opportunities for producing and using normal development free of the assumptions of the instructive-permissive distinction. These opportunities are afforded by recent developments, which include new ways of producing standards incorporating more natural variation and being based on function rather than structure, and the ability to produce, store, and process large quantities of data. (shrink)