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  1. Unintended Intrauterine Death and Preterm Delivery: What Does Philosophy Have to Offer?Nicholas Colgrove - 2023 - Journal of Medicine and Philosophy 48 (3):195-208.
    This special issue of the Journal of Medicine and Philosophy focuses on unintended intrauterine death (UID) and preterm delivery (both phenomena that are commonly—and unhelpfully—referred to as “miscarriage,” “spontaneous abortion,” and “early pregnancy loss”). In this essay, I do two things. First, I outline contributors’ arguments. Most contributors directly respond to “inconsistency arguments,” which purport to show that abortion opponents are unjustified in their comparative treatment of abortion and UID. Contributors to this issue show that such arguments often rely on (...)
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  • Mitochondrial replacement techniques for treating infertility.Esther Braun - forthcoming - Journal of Medical Ethics.
    Mitochondrial replacement techniques (MRTs) usually aim to prevent the genetic transmission of maternally inherited mitochondrial diseases. Until now, only the UK and Australia have implemented specific legal regulations of MRTs. In both countries, clinical trials on these techniques are only permissible for cases with a high risk of severe mitochondrial disease in the offspring. However, these techniques can also be applied to treat infertility, especially for older women with impaired oocyte quality. In some countries without legal regulation of these techniques, (...)
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  • Initial heritable genome editing: mapping a responsible pathway from basic research to the clinic.Robert Ranisch, Katharina Trettenbach & Gardar Arnason - 2023 - Medicine, Health Care and Philosophy 26 (1):21-35.
    Following the Second Summit on Human Gene Editing in Hong Kong in 2018, where the birth of two girls with germline genome editing was revealed, the need for a responsible pathway to the clinical application of human germline genome editing has been repeatedly emphasised. This paper aims to contribute to the ongoing discussion on research ethics issues in germline genome editing by exploring key issues related to the initial applications of CRISPR in reproductive medicine. Following an overview of the current (...)
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  • Gene editing, identity and benefit.Thomas Douglas & Katrien Devolder - 2022 - Philosophical Quarterly 72 (2):305-325.
    Some suggest that gene editing human embryos to prevent genetic disorders will be in one respect morally preferable to using genetic selection for the same purpose: gene editing will benefit particular future persons, while genetic selection would merely replace them. We first construct the most plausible defence of this suggestion—the benefit argument—and defend it against a possible objection. We then advance another objection: the benefit argument succeeds only when restricted to cases in which the gene-edited child would have been brought (...)
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  • Gene Editing, Identity and Benefit.Thomas Douglas & Katrien Devolder - 2022 - Philosophical Quarterly 72 (2):305-325.
    Some suggest that gene editing human embryos to prevent genetic disorders will be in one respect morally preferable to using genetic selection for the same purpose: gene editing will benefit particular future persons, while genetic selection would merely replace them. We first construct the most plausible defence of this suggestion—the benefit argument—and defend it against a possible objection. We then advance another objection: the benefit argument succeeds only when restricted to cases in which the gene-edited child would have been brought (...)
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  • Trojan Horses, Clinical Utility, and Parfitian Puzzles.Bryan Cwik - 2022 - American Journal of Bioethics 22 (9):16-18.
    There is a burgeoning corner of the philosophical literature on germline gene editing (GGE) about whether GGE is “person-affecting” or “identify-affecting.” The distinction between actions that aff...
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