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New Mechanistic Explanation and the Need for Explanatory Constraints

In Ken Aizawa & Carl Gillett (eds.), Scientific Composition and Metaphysical Ground. London: Palgrave-Macmillan. pp. 41-74 (2016)

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  1. Mechanisms and downward causation.Max Kistler - 2009 - Philosophical Psychology 22 (5):595-609.
    Experimental investigation of mechanisms seems to make use of causal relations that cut across levels of composition. In bottom-up experiments, one intervenes on parts of a mechanism to observe the whole; in top-down experiments, one intervenes on the whole mechanism to observe certain parts of it. It is controversial whether such experiments really make use of interlevel causation, and indeed whether the idea of causation across levels is even conceptually coherent. Craver and Bechtel have suggested that interlevel causal claims can (...)
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  • The cement of the universe.John Leslie Mackie - 1974 - Oxford,: Clarendon Press.
    Studies causation both as a concept and as it is 'in the objects.' Offers new accounts of the logic of singular causal statements, the form of causal regularities, the detection of causal relationships, the asymmetry of cause and effect, and necessary connection, and it relates causation to functional and statistical laws and to teleology.
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  • A Glimpse of the Secret Connexion: Harmonizing Mechanisms with Counterfactuals.Stathis Psillos - 2003 - Perspectives on Science 12 (3):288-319.
    Among the current philosophical attempts to understand causation two seem to be the most prominent. The first is James Woodward’s counterfactual approach; the second is the mechanistic approach advocated by Peter Machamer, Lindley Darden, Carl Craver, Jim Bogen and Stuart Glennan. The counterfactual approach takes it that causes make a difference to their effects, where this difference-making is cashed out in terms of actual and counterfactual interventions. The mechanistic approach takes it that two events are causally related if and only (...)
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  • Making things happen: a theory of causal explanation.James F. Woodward - 2003 - New York: Oxford University Press.
    Woodward's long awaited book is an attempt to construct a comprehensive account of causation explanation that applies to a wide variety of causal and explanatory claims in different areas of science and everyday life. The book engages some of the relevant literature from other disciplines, as Woodward weaves together examples, counterexamples, criticisms, defenses, objections, and replies into a convincing defense of the core of his theory, which is that we can analyze causation by appeal to the notion of manipulation.
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  • Law and explanation in biology: Invariance is the kind of stability that matters.James Woodward - 2001 - Philosophy of Science 68 (1):1-20.
    This paper develops an account of explanation in biology which does not involve appeal to laws of nature, at least as traditionally conceived. Explanatory generalizations in biology must satisfy a requirement that I call invariance, but need not satisfy most of the other standard criteria for lawfulness. Once this point is recognized, there is little motivation for regarding such generalizations as laws of nature. Some of the differences between invariance and the related notions of stability and resiliency, due respectively to (...)
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  • Mechanistic explanation at the limit.Jonathan Waskan - 2011 - Synthese 183 (3):389-408.
    Resurgent interest in both mechanistic and counterfactual theories of explanation has led to a fair amount of discussion regarding the relative merits of these two approaches. James Woodward is currently the pre-eminent counterfactual theorist, and he criticizes the mechanists on the following grounds: Unless mechanists about explanation invoke counterfactuals, they cannot make sense of claims about causal interactions between mechanism parts or of causal explanations put forward absent knowledge of productive mechanisms. He claims that these shortfalls can be offset if (...)
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  • Synthesizing activities and interactions in the concept of a mechanism.James G. Tabery - 2004 - Philosophy of Science 71 (1):1-15.
    Stuart Glennan, and the team of Peter Machamer, Lindley Darden, and Carl Craver have recently provided two accounts of the concept of a mechanism. The main difference between these two versions rests on how the behavior of the parts of the mechanism is conceptualized. Glennan considers mechanisms to be an interaction of parts, where the interaction between parts can be characterized by direct, invariant, change-relating generalizations. Machamer, Darden, and Craver criticize traditional conceptualizations of mechanisms which are based solely on parts (...)
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  • Thinking about evolutionary mechanisms: Natural selection.Robert Skipper & Roberta Millstein - 2004 - Studies in History and Philosophy of Biological and Biomedical Sciences 36 (2):327-347.
    This paper explores whether natural selection, a putative evolutionary mechanism, and a main one at that, can be characterized on either of the two dominant conceptions of mechanism, due to Glennan and the team of Machamer, Darden, and Craver, that constitute the “new mechanistic philosophy.” The results of the analysis are that neither of the dominant conceptions of mechanism adequately captures natural selection. Nevertheless, the new mechanistic philosophy possesses the resources for an understanding of natural selection under the rubric.
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  • Scientific Explanation and the Causal Structure of the World.Wesley C. Salmon - 1984 - Princeton University Press.
    The philosophical theory of scientific explanation proposed here involves a radically new treatment of causality that accords with the pervasively statistical character of contemporary science. Wesley C. Salmon describes three fundamental conceptions of scientific explanation--the epistemic, modal, and ontic. He argues that the prevailing view is untenable and that the modal conception is scientifically out-dated. Significantly revising aspects of his earlier work, he defends a causal/mechanical theory that is a version of the ontic conception. Professor Salmon's theory furnishes a robust (...)
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  • A deductive-nomological model of probabilistic explanation.Peter Railton - 1978 - Philosophy of Science 45 (2):206-226.
    It has been the dominant view that probabilistic explanations of particular facts must be inductive in character. I argue here that this view is mistaken, and that the aim of probabilistic explanation is not to demonstrate that the explanandum fact was nomically expectable, but to give an account of the chance mechanism(s) responsible for it. To this end, a deductive-nomological model of probabilistic explanation is developed and defended. Such a model has application only when the probabilities occurring in covering laws (...)
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  • The Concept of Mechanism in Biology.Daniel J. Nicholson - 2012 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 43 (1):152-163.
    The concept of mechanism in biology has three distinct meanings. It may refer to a philosophical thesis about the nature of life and biology (‘mechanicism’), to the internal workings of a machine-like structure (‘machine mechanism’), or to the causal explanation of a particular phenomenon (‘causal mechanism’). In this paper I trace the conceptual evolution of ‘mechanism’ in the history of biology, and I examine how the three meanings of this term have come to be featured in the philosophy of biology, (...)
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  • Dimensions of scientific law.Sandra D. Mitchell - 2000 - Philosophy of Science 67 (2):242-265.
    Biological knowledge does not fit the image of science that philosophers have developed. Many argue that biology has no laws. Here I criticize standard normative accounts of law and defend an alternative, pragmatic approach. I argue that a multidimensional conceptual framework should replace the standard dichotomous law/ accident distinction in order to display important differences in the kinds of causal structure found in nature and the corresponding scientific representations of those structures. To this end I explore the dimensions of stability, (...)
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  • Thinking about mechanisms.Peter Machamer, Lindley Darden & Carl F. Craver - 2000 - Philosophy of Science 67 (1):1-25.
    The concept of mechanism is analyzed in terms of entities and activities, organized such that they are productive of regular changes. Examples show how mechanisms work in neurobiology and molecular biology. Thinking in terms of mechanisms provides a new framework for addressing many traditional philosophical issues: causality, laws, explanation, reduction, and scientific change.
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  • Activities and causation: The metaphysics and epistemology of mechanisms.Peter Machamer - 2004 - International Studies in the Philosophy of Science 18 (1):27 – 39.
    This article deals with mechanisms conceived as composed of entities and activities. In response to many perplexities about the nature of activities, a number of arguments are developed concerning their epistemic and ontological status. Some questions concerning the relations between cause and causal explanation and mechanisms are also addressed.
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  • Three kinds of new mechanism.Arnon Levy - 2013 - Biology and Philosophy 28 (1):99-114.
    I distinguish three theses associated with the new mechanistic philosophy – concerning causation, explanation and scientific methodology. Advocates of each thesis are identified and relationships among them are outlined. I then look at some recent work on natural selection and mechanisms. There, attention to different kinds of New Mechanism significantly affects of what is at stake.
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  • Abstraction and the Organization of Mechanisms.Arnon Levy & William Bechtel - 2013 - Philosophy of Science 80 (2):241-261.
    Proponents of mechanistic explanation all acknowledge the importance of organization. But they have also tended to emphasize specificity with respect to parts and operations in mechanisms. We argue that in understanding one important mode of organization—patterns of causal connectivity—a successful explanatory strategy abstracts from the specifics of the mechanism and invokes tools such as those of graph theory to explain how mechanisms with a particular mode of connectivity will behave. We discuss the connection between organization, abstraction, and mechanistic explanation and (...)
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  • Can mechanisms really replace laws of nature?Bert Leuridan - 2010 - Philosophy of Science 77 (3):317-340.
    Today, mechanisms and mechanistic explanation are very popular in philosophy of science and are deemed a welcome alternative to laws of nature and deductive‐nomological explanation. Starting from Mitchell's pragmatic notion of laws, I cast doubt on their status as a genuine alternative. I argue that (1) all complex‐systems mechanisms ontologically must rely on stable regularities, while (2) the reverse need not hold. Analogously, (3) models of mechanisms must incorporate pragmatic laws, while (4) such laws themselves need not always refer to (...)
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  • Dynamical Models: An Alternative or Complement to Mechanistic Explanations?David M. Kaplan & William Bechtel - 2011 - Topics in Cognitive Science 3 (2):438-444.
    Abstract While agreeing that dynamical models play a major role in cognitive science, we reject Stepp, Chemero, and Turvey's contention that they constitute an alternative to mechanistic explanations. We review several problems dynamical models face as putative explanations when they are not grounded in mechanisms. Further, we argue that the opposition of dynamical models and mechanisms is a false one and that those dynamical models that characterize the operations of mechanisms overcome these problems. By briefly considering examples involving the generation (...)
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  • From an ontological point of view.John Heil - 2003 - New York: Oxford University Press.
    From an Ontological Point of View is a highly original and accessible exploration of fundamental questions about what there is. John Heil discusses such issues as whether the world includes levels of reality; the nature of objects and properties; the demands of realism; what makes things true; qualities, powers, and the relation these bear to one another. He advances an account of the fundamental constituents of the world around us, and applies this account to problems that have plagued recent work (...)
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  • Regularity Constitution and the Location of Mechanistic Levels.Jens Harbecke - 2015 - Foundations of Science 20 (3):323-338.
    This paper discusses the role of levels and level-bound theoretical terms in neurobiological explanations under the presupposition of a regularity theory of constitution. After presenting the definitions for the constitution relation and the notion of a mechanistic level in the sense of the regularity theory, the paper develops a set of inference rules that allow to determine whether two mechanisms referred to by one or more accepted explanations belong to the same level, or to different levels. The rules are characterized (...)
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  • Rethinking mechanistic explanation.Stuart Glennan - 2002 - Proceedings of the Philosophy of Science Association 2002 (3):S342-353.
    Philosophers of science typically associate the causal-mechanical view of scientific explanation with the work of Railton and Salmon. In this paper I shall argue that the defects of this view arise from an inadequate analysis of the concept of mechanism. I contrast Salmon's account of mechanisms in terms of the causal nexus with my own account of mechanisms, in which mechanisms are viewed as complex systems. After describing these two concepts of mechanism, I show how the complex-systems approach avoids certain (...)
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  • Rethinking Mechanistic Explanation.Stuart Glennan - 2002 - Philosophy of Science 69 (S3):S342-S353.
    Philosophers of science typically associate the causal-mechanical view of scientific explanation with the work of Railton and Salmon. In this paper I shall argue that the defects of this view arise from an inadequate analysis of the concept of mechanism. I contrast Salmon's account of mechanisms in terms of the causal nexus with my own account of mechanisms, in which mechanisms are viewed as complex systems. After describing these two concepts of mechanism, I show how the complex-systems approach avoids certain (...)
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  • Mechanisms, Causes, and the Layered Model of the World.Stuart Glennan - 2010 - Philosophy and Phenomenological Research 81 (2):362-381.
    Most philosophical accounts of causation take causal relations to obtain between individuals and events in virtue of nomological relations between properties of these individuals and events. Such views fail to take into account the consequences of the fact that in general the properties of individuals and events will depend upon mechanisms that realize those properties. In this paper I attempt to rectify this failure, and in so doing to provide an account of the causal relevance of higher-level properties. I do (...)
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  • Modeling mechanisms.Stuart Glennan - 2005 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 36 (2):443-464.
    Philosophers of science increasingly believe that much of science is concerned with understanding the mechanisms responsible for the production of natural phenomena. An adequate understanding of scientific research requires an account of how scientists develop and test models of mechanisms. This paper offers a general account of the nature of mechanical models, discussing the representational relationship that holds between mechanisms and their models as well as the techniques that can be used to test and refine such models. The analysis is (...)
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  • Ephemeral Mechanisms and Historical Explanation.Stuart Glennan - 2010 - Erkenntnis 72 (2):251-266.
    While much of the recent literature on mechanisms has emphasized the superiority of mechanisms and mechanistic explanation over laws and nomological explanation, paradigmatic mechanisms—e.g., clocks or synapses—actually exhibit a great deal of stability in their behavior. And while mechanisms of this kind are certainly of great importance, there are many events that do not occur as a consequence of the operation of stable mechanisms. Events of natural and human history are often the consequence of causal processes that are ephemeral and (...)
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  • The Cement of the Universe.John Earman & J. L. Mackie - 1976 - Philosophical Review 85 (3):390.
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  • Causality and conserved quantities: A reply to salmon.Phil Dowe - 1995 - Philosophy of Science 62 (2):321-333.
    In a recent paper (1994) Wesley Salmon has replied to criticisms (e.g., Dowe 1992c, Kitcher 1989) of his (1984) theory of causality, and has offered a revised theory which, he argues, is not open to those criticisms. The key change concerns the characterization of causal processes, where Salmon has traded "the capacity for mark transmission" for "the transmission of an invariant quantity." Salmon argues against the view presented in Dowe (1992c), namely that the concept of "possession of a conserved quantity" (...)
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  • Thinking again about biological mechanisms.Lindley Darden - 2008 - Philosophy of Science 75 (5):958-969.
    The new research program to understand mechanisms in biology has developed rapidly in the last 10 years. Reconsideration of the characterization of mechanisms in biology in the light of this recent work is now in order. This article discusses the perspectival aspect of the characterization of mechanisms, refinements in claims about working entities and kinds of activities, challenges and responses to claims about regularity, productive continuity, and the organizational aspects of a mechanism, and issues about representations of mechanisms in schemas (...)
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  • When mechanistic models explain.Carl F. Craver - 2006 - Synthese 153 (3):355-376.
    Not all models are explanatory. Some models are data summaries. Some models sketch explanations but leave crucial details unspecified or hidden behind filler terms. Some models are used to conjecture a how-possibly explanation without regard to whether it is a how-actually explanation. I use the Hodgkin and Huxley model of the action potential to illustrate these ways that models can be useful without explaining. I then use the subsequent development of the explanation of the action potential to show what is (...)
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  • Constitutive Explanatory Relevance.Carl Craver - 2007 - Journal of Philosophical Research 32:3-20.
    In what sense are the activities and properties of components in a mechanism explanatorily relevant to the behavior of a mechanism as a whole? I articulate this problem, the problem of constitutive relevance, and I show that it must be solved if we are to understand mechanisms and mechanistic explanation. I argue against some putative solutions to the problem of constitutive relevance, and I sketch a positive account according to which relevance is analyzed in terms ofrelationships of mutual manipulability between (...)
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  • Constitutive Explanatory Relevance.Carl Craver - 2007 - Journal of Philosophical Research 32:3-20.
    In what sense are the activities and properties of components in a mechanism explanatorily relevant to the behavior of a mechanism as a whole? I articulate this problem, the problem of constitutive relevance, and I show that it must be solved if we are to understand mechanisms and mechanistic explanation. I argue against some putative solutions to the problem of constitutive relevance, and I sketch a positive account according to which relevance is analyzed in terms ofrelationships of mutual manipulability between (...)
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  • Mechanisms and Counterfactuals: a Different Glimpse of the Connexion.Rafaella Campaner - 2006 - Philosophica 77 (1).
    Ever since Wesley Salmon’s theory, the mechanical approach to causality has found an increasing number of supporters who have developed it in different directions. Mechanical views such as those advanced by Stuart Glennan, Jim Bogen and Peter Machamer, Lindley Darden and Carl Craver have met with broad consensus in recent years. This paper analyses the main features of these mechanical positions and some of the major problems they still face, referring to the latest debate on mechanisms, causal explanation and the (...)
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  • Regularities and causality; generalizations and causal explanations.Jim Bogen - 2005 - Studies in History and Philosophy of Biological and Biomedical Sciences 36 (2):397-420.
    Machamer, Darden, and Craver argue that causal explanations explain effects by describing the operations of the mechanisms which produce them. One of this paper’s aims is to take advantage of neglected resources of Mechanism to rethink the traditional idea that actual or counterfactual natural regularities are essential to the distinction between causal and non-causal co-occurrences, and that generalizations describing natural regularities are essential components of causal explanations. I think that causal productivity and regularity are by no means the same thing, (...)
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  • Causally productive activities.Jim Bogen - 2008 - Studies in History and Philosophy of Science Part A 39 (1):112-123.
    This paper suggests and discusses an answer to the following question: What distinguishes causal from non-causal or coincidental co-occurrences? The answer derives from Elizabeth Anscombe’s idea that causality is a highly abstract concept whose meaning derives from our understanding of specific causally productive activities, and from her rejection of the assumption that causality can be informatively understood in terms of actual or counterfactual regularities.Keywords: Elizabeth Anscombe; Causality; Explanation; Inhibition.
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  • Mechanism and Biological Explanation.William Bechtel - 2011 - Philosophy of Science 78 (4):533-557.
    This article argues that the basic account of mechanism and mechanistic explanation, involving sequential execution of qualitatively characterized operations, is itself insufficient to explain biological phenomena such as the capacity of living organisms to maintain themselves as systems distinct from their environment. This capacity depends on cyclic organization, including positive and negative feedback loops, which can generate complex dynamics. Understanding cyclically organized mechanisms with complex dynamics requires coordinating research directed at decomposing mechanisms into parts and operations with research using computational (...)
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  • Explanation: a mechanist alternative.William Bechtel & Adele Abrahamsen - 2005 - Studies in History and Philosophy of Biological and Biomedical Sciences 36 (2):421-441.
    Explanations in the life sciences frequently involve presenting a model of the mechanism taken to be responsible for a given phenomenon. Such explanations depart in numerous ways from nomological explanations commonly presented in philosophy of science. This paper focuses on three sorts of differences. First, scientists who develop mechanistic explanations are not limited to linguistic representations and logical inference; they frequently employ diagrams to characterize mechanisms and simulations to reason about them. Thus, the epistemic resources for presenting mechanistic explanations are (...)
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  • Nuts and Bolts for the Social Sciences.Jon Elster - 1989 - Cambridge University Press.
    This 1989 book is intended as an introductory survey of the philosophy of the social sciences. It is essentially a work of exposition which offers a toolbox of mechanisms - nuts and bolts, cogs and wheels - that can be used to explain complex social phenomena. Within a brief compass, Jon Elster covers a vast range of topics. His point of departure is the conflict we all face between our desires and our opportunities. How can rational choice theory help us (...)
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  • Representing and Intervening.Ian Hacking - 1983 - British Journal for the Philosophy of Science 35 (4):381-390.
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  • Embryology, Epigenesis and Evolution: Taking Development Seriously.Jason Scott Robert - 2004 - Cambridge University Press.
    Historically, philosophers of biology have tended to sidestep the problem of development by focusing primarily on evolutionary biology and, more recently, on molecular biology and genetics. Quite often too, development has been misunderstood as simply, or even primarily, a matter of gene activation and regulation. Nowadays a growing number of philosophers of science are focusing their analyses on the complexities of development, and in Embryology, Epigenesis and Evolution Jason Scott Robert explores the nature of development against current trends in biological (...)
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  • Explaining the Brain.Carl F. Craver - 2007 - Oxford, GB: Oxford University Press.
    Carl F. Craver investigates what we are doing when we use neuroscience to explain what's going on in the brain. When does an explanation succeed and when does it fail? Craver offers explicit standards for successful explanation of the workings of the brain, on the basis of a systematic view about what neuroscientific explanations are.
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  • Depth: An Account of Scientific Explanation.Michael Strevens - 2008 - Cambridge, Mass.: Harvard University Press.
    Approaches to explanation -- Causal and explanatory relevance -- The kairetic account of /D making -- The kairetic account of explanation -- Extending the kairetic account -- Event explanation and causal claims -- Regularity explanation -- Abstraction in regularity explanation -- Approaches to probabilistic explanation -- Kairetic explanation of frequencies -- Kairetic explanation of single outcomes -- Looking outward -- Looking inward.
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  • Representing and Intervening: Introductory Topics in the Philosophy of Natural Science.Ian Hacking - 1983 - New York: Cambridge University Press.
    This 1983 book is a lively and clearly written introduction to the philosophy of natural science, organized around the central theme of scientific realism. It has two parts. 'Representing' deals with the different philosophical accounts of scientific objectivity and the reality of scientific entities. The views of Kuhn, Feyerabend, Lakatos, Putnam, van Fraassen, and others, are all considered. 'Intervening' presents the first sustained treatment of experimental science for many years and uses it to give a new direction to debates about (...)
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  • From an Ontological Point of View.John Heil - 2003 - Philosophy 79 (309):491-494.
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  • Unity of Science as a Working Hypothesis.Paul Oppenheim & Hilary Putnam - 1958 - Minnesota Studies in the Philosophy of Science 2:3-36.
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  • Two concepts of causation.Ned Hall - 2004 - In John Collins, Ned Hall & Laurie Paul (eds.), Causation and Counterfactuals. MIT Press. pp. 225-276.
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  • Defending Robustness: The Bacterial Mesosome as a Test Case.Sylvia Culp - 1994 - PSA: Proceedings of the Biennial Meeting of the Philosophy of Science Association 1994:46 - 57.
    Rasmussen (1993) argues that, because electron microscopists did not use robustness and would not have been warranted in using it as a criterion for the reality or the artifactuality of mesosomes, the bacterial mesosome serves as a test case for robustness that it fails. I respond by arguing that a more complete reading of the research literature on the mesosome shows that ultimately the more robust body of data did not support the mesosome and that electron microscopists used and were (...)
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  • Mental mechanisms: Philosophical perspectives on the sciences of cognition and the brain.William P. Bechtel - manuscript
    1. The Naturalistic Turn in Philosophy of Science 2. The Framework of Mechanistic Explanation: Parts, Operations, and Organization 3. Representing and Reasoning About Mechanisms 4. Mental Mechanisms: Mechanisms that Process Information 5. Discovering Mental Mechanisms 6 . Summary.
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