In this paper, a prototype of a Decision Support System (DSS) is proposed for providing the knowledge for optimizing the newly adopted e-learning education strategy in educational institutions. If an educational institution adopted e-learning as a new strategy, it should undertake a preliminary evaluation to determine the percentage of success and areas of weakness of this strategy. If this evaluation is done manually, it would not be an easy task to do and would not provide knowledge about all pitfall symptoms. (...) The proposed DSS is based on exploration (mining) of knowledge from large amounts of data yielded from the operating the institution to its business. This knowledge can be used to guide and optimize any new business strategy implemented by the institution. The proposed DSS involves Database engine, Data Mining engine and Artificial Intelligence engine. All these engines work together in order to extract the knowledge necessary to improve the effectiveness of any strategy, including e-learning. (shrink)