10 found
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  1. Multiplex Parenting: IVG and the Generations to Come.César Palacios-González, John Harris & Giuseppe Testa - 2014 - Journal of Medical Ethics 40 (11):752-758.
    Recent breakthroughs in stem cell differentiation and reprogramming suggest that functional human gametes could soon be created in vitro. While the ethical debate on the uses of in vitro generated gametes (IVG) was originally constrained by the fact that they could be derived only from embryonic stem cell lines, the advent of somatic cell reprogramming, with the possibility to easily derive human induced pluripotent stem cells from any individual, affords now a major leap in the feasibility of IVG derivation and (...)
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  2.  76
    Mitochondrial Replacement Techniques and Mexico’s Rule of Law: On the Legality of the First Maternal Spindle Transfer Case.César Palacios-González - 2017 - Journal of Law and the Biosciences 4 (1):50–69.
    News about the first baby born after a mitochondrial replacement technique (MRT; specifically maternal spindle transfer) broke on September 27, 2016 and, in a matter of hours, went global. Of special interest was the fact that the mitochondrial replacement procedure happened in Mexico. One of the scientists behind this world first was quoted as having said that he and his team went to Mexico to carry out the procedure because, in Mexico, there are no rules. In this paper, we explore (...)
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  3. Resource Allocation, Treatment, Disclosure, and Mitochondrial Replacement Techniques: Some Comments on de Melo-Martin and Harris.César Palacios-gonzález - 2017 - Cambridge Quarterly of Healthcare Ethics 26 (2):278-287.
    Some Comments on de Melo-Martin and Harris.
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  4.  66
    Author's Response to Peer Commentaries: Mexico's Rule of Law and MRTs.César Palacios-González & María de Jesús Medina-Arellano - 2017 - Journal of Law and the Biosciences 4 (3):623–629.
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  5. Chimeras Intended for Human Gamete Production: An Ethical Alternative?César Palacios-González - 2017 - Reproductive Biomedicine Online 35 (4):387-390.
    Human eggs for basic, fertility and stem-cell research are in short supply. Many experiments that require their use cannot be carried out at present, and, therefore, the benefits that could emerge from these are either delayed or never materialise. This state of affairs is problematic for scientists and patients worldwide, and it is a matter that needs our attention. Recent advances in chimera research have opened the possibility of creating human/non-human animal chimeras intended for human gamete production (chimeras-IHGP). In this (...)
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  6. Genetic Parenthood and Causation: An Objection to Douglas and Devolder’s Modified Direct Proportionate Genetic Descent Account.César Palacios-González - 2019 - Bioethics 33 (9):1085-1090.
    In a recent publication Tom Douglas and Katrien Devolder have proposed a new account of genetic parenthood, building on the work of Heidi Mertes. Douglas and Devolder’s account aims to solve, among other things, the question of who are the genetic parents of an individual created through somatic cell nuclear transfer (i.e. cloning): (a) the nuclear DNA provider or (b) the progenitors of the nuclear DNA provider. Such a question cannot be answered by simply appealing to the folk account of (...)
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  7.  91
    Mexico and Mitochondrial Replacement Techniques: What a Mess.César Palacios-González - 2018 - British Medical Bulletin 128.
    Abstract Background The first live birth following the use of a new reproductive technique, maternal spindle transfer (MST), which is a mitochondrial replacement technique (MRT), was accomplished by dividing the execution of the MST procedure between two countries, the USA and Mexico. This was done in order to avoid US legal restrictions on this technique. -/- Sources of data Academic articles, news articles, documents obtained through freedom of information requests, laws, regulations and national reports. -/- Areas of agreement MRTs are (...)
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  8. Mitochondrial Replacement Techniques: Genetic Relatedness, Gender Implications, and Justice.César Palacios-González & Tetsuya Ishii - 2017 - Gender and the Genome 1 (4):1-6.
    In 2015 the United Kingdom (UK) became the first nation to legalize egg and zygotic nuclear transfer procedures using mitochondrial replacement techniques (MRTs) to prevent the maternal transmission of serious mitochondrial DNA diseases to offspring. These techniques are a form of human germline genetic modification and can happen intentionally if female embryos are selected during the MRT clinical process, either through sperm selection or preimplantation genetic diagnosis (PGD). In the same year, an MRT was performed by a United States (U.S.)-based (...)
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  9.  10
    Reproductive Genome Editing Interventions Are Therapeutic, Sometimes.César Palacios-González - forthcoming - Bioethics.
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  10.  16
    Beyond Individual Triage: Regional Allocation of Life-Saving Resources such as Ventilators in Public Health Emergencies.Jonathan Pugh, Dominic Wilkinson, Cesar Palacios-Gonzalez & Julian Savulescu - forthcoming - Health Care Analysis:1-20.
    In the first wave of the COVID-19 pandemic, healthcare workers in some countries were forced to make distressing triaging decisions about which individual patients should receive potentially life-saving treatment. Much of the ethical discussion prompted by the pandemic has concerned which moral principles should ground our response to these individual triage questions. In this paper we aim to broaden the scope of this discussion by considering the ethics of broader structural allocation decisions raised by the COVID-19 pandemic. More specifically, we (...)
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