Results for 'Dorsolateral prefrontal cortex'

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  1. Dreams: An Empirical Way to Settle the Discussion Between Cognitive and Non-Cognitive Theories of Consciousness.Miguel Ángel Sebastián - 2014 - Synthese 191 (2):263-285.
    Cognitive theories claim, whereas non-cognitive theories deny, that cognitive access is constitutive of phenomenology. Evidence in favor of non-cognitive theories has recently been collected by Block and is based on the high capacity of participants in partial-report experiments compared to the capacity of the working memory. In reply, defenders of cognitive theories have searched for alternative interpretations of such results that make visual awareness compatible with the capacity of the working memory; and so the conclusions of such experiments remain controversial. (...)
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  2. Not a HOT Dream.Miguel Ángel Sebastián - 2013 - In Consciousness Inside and Out: Phenomenology, Neuroscience, and the Nature of Experience. Springer Studies in Brain and Mind.
    Higher-Order Thought (HOT) theories of consciousness maintain that the kind of awareness necessary for phenomenal consciousness depends on the cognitive accessibility that underlies reporting. -/- There is empirical evidence strongly suggesting that the cognitive accessibility that underlies the ability to report visual experiences depends on the activity of the dorsolateral prefrontal cortex (dlPFC). This area, however, is highly deactivated during the conscious experiences we have during sleep: dreams. HOT theories are jeopardized, as I will argue. I will (...)
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  3. Damage to the Prefrontal Cortex Increases Utilitarian Moral Judgements.Michael Koenigs, Liane Young, Ralph Adolphs, Daniel Tranel, Fiery Cushman, Marc Hauser & Antonio Damasio - 2007 - Nature 446 (7138):908-911.
    The psychological and neurobiological processes underlying moral judgement have been the focus of many recent empirical studies1–11. Of central interest is whether emotions play a causal role in moral judgement, and, in parallel, how emotion-related areas of the brain contribute to moral judgement. Here we show that six patients with focal bilateral damage to the ventromedial prefrontal cortex (VMPC), a brain region necessary for the normal generation of emotions and, in particular, social emotions12–14, produce an abnor- mally ‘utilitarian’ (...)
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  4. Minority Reports: Consciousness and the Prefrontal Cortex.Matthias Michel & Jorge Morales - 2020 - Mind and Language 35 (4):493-513.
    Whether the prefrontal cortex is part of the neural substrates of consciousness is currently debated. Against prefrontal theories of consciousness, many have argued that neural activity in the prefrontal cortex does not correlate with consciousness but with subjective reports. We defend prefrontal theories of consciousness against this argument. We surmise that the requirement for reports is not a satisfying explanation of the difference in neural activity between conscious and unconscious trials, and that prefrontal (...)
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  5. A Role for the Prefrontal Cortex in Supporting Singular Demonstrative Reference.Felipe Nogueira de Carvalho & Albert Newen - 2019 - Journal of Consciousness Studies 26 (11-12):133-156.
    One of the most pressing questions concerning singular demonstrative mental contents is what makes their content singular: that is to say, what makes it the case that individual objects are the representata of these mental states. Many philosophers have required sophisticated intellectual capacities for singular content to be possible, such as the possession of an elaborate scheme of space and time. A more recent reaction to this strategy proposes to account for singular content solely on the basis of empirical models (...)
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  6. Influence of the Cortical Midline Structures on Moral Emotion and Motivation in Moral Decision-Making.Hyemin Han, Jingyuan E. Chen, Changwoo Jeong & Gary H. Glover - 2016 - Behavioural Brain Research 302:237-251.
    The present study aims to examine the relationship between the cortical midline structures (CMS), which have been regarded to be associated with selfhood, and moral decision making processes at the neural level. Traditional moral psychological studies have suggested the role of moral self as the moderator of moral cognition, so activity of moral self would present at the neural level. The present study examined the interaction between the CMS and other moral-related regions by conducting psycho-physiological interaction analysis of functional images (...)
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  7.  63
    Domain-General and Domain-Specific Patterns of Activity Support Metacognition in Human Prefrontal Cortex.Jorge Morales, Hakwan Lau & Stephen M. Fleming - 2018 - The Journal of Neuroscience 38 (14):3534-3546.
    Metacognition is the capacity to evaluate the success of one's own cognitive processes in various domains; for example, memory and perception. It remains controversial whether metacognition relies on a domain-general resource that is applied to different tasks or if self-evaluative processes are domain specific. Here, we investigated this issue directly by examining the neural substrates engaged when metacognitive judgments were made by human participants of both sexes during perceptual and memory tasks matched for stimulus and performance characteristics. By comparing patterns (...)
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  8. Abnormal Ventromedial Prefrontal Cortex Function in Children With Psychopathic Traits During Reversal Learning.Elizabeth C. Finger, Abigail A. Marsh, Derek G. Mitchell, Marguerite E. Reid, Courtney Sims, Salima Budhani, David S. Kosson, Gang Chen, Kenneth E. Towbin, Ellen Leibenluft, Daniel S. Pine & James R. Blair - 2008 - Archives of General Psychiatry 65: 586–594.
    Context — Children and adults with psychopathic traits and conduct or oppositional defiant disorder demonstrate poor decision making and are impaired in reversal learning. However, the neural basis of this impairment has not previously been investigated. Furthermore, despite high comorbidity of psychopathic traits and attention deficit/hyperactivity disorder, to our knowledge, no research has attempted to distinguish neural correlates of childhood psychopathic traits and attention-deficit/hyperactivity disorder. Objective—To determine the neural regions that underlie the reversal learning impairments in children with psychopathic traits (...)
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  9. The Emergence of Emotions.Richard Sieb - 2013 - Activitas Nervosa Superior 55 (4):115-145.
    Emotion is conscious experience. It is the affective aspect of consciousness. Emotion arises from sensory stimulation and is typically accompanied by physiological and behavioral changes in the body. Hence an emotion is a complex reaction pattern consisting of three components: a physiological component, a behavioral component, and an experiential (conscious) component. The reactions making up an emotion determine what the emotion will be recognized as. Three processes are involved in generating an emotion: (1) identification of the emotional significance of a (...)
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  10. Does the Prefrontal Cortex Play an Essential Role in Consciousness? Insights From Intracranial Electrical Stimulation of the Human Brain.Omri Raccah, Ned Block & Kieran C. R. Fox - 2021 - Journal of Neuroscience 1 (41):2076-2087.
    A central debate in philosophy and neuroscience pertains to whether PFC activity plays an essential role in the neural basis of consciousness. Neuroimaging and electrophysiology studies have revealed that the contents of conscious perceptual experience can be successfully decoded from PFC activity, but these findings might be confounded by post- perceptual cognitive processes, such as thinking, reasoning, and decision-making, that are not necessary for con- sciousness. To clarify the involvement of the PFC in consciousness, we present a synthesis of research (...)
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  11. I Cannot Tell You (Everything) About My Dreams: Reply to Ivanowich and Weisberg.Miguel Ángel Sebastián - 2013 - In Consciousness Inside and Out: Phenomenology, Neuroscience, and the Nature of Experience. Springer Studies in Brain and Mind.
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  12. Prefrontal Lesion Evidence Against Higher-Order Theories of Consciousness.Benjamin Kozuch - 2014 - Philosophical Studies 167 (3):721-746.
    According to higher-order theories of consciousness, a mental state is conscious only when represented by another mental state. Higher-order theories must predict there to be some brain areas (or networks of areas) such that, because they produce (the right kind of) higher-order states, the disabling of them brings about deficits in consciousness. It is commonly thought that the prefrontal cortex produces these kinds of higher-order states. In this paper, I first argue that this is likely correct, meaning that, (...)
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  13.  52
    Info-Relational Cognitive Operability of the Posterior Cingulate Cortex According to the Informational Model of Consciousness.Florin Gaiseanu - 2020 - International Journal of Psychological and Brain Sciences 5 (4):61-68.
    Based on the analysis of the accumulated experimental data and on the informational concepts of the Informational Model of Consciousness (IMC), in this article is presented an informational modeling of the operability of the posterior cingulate cortex (PCC). Examination of the experimental results obtained with the modern non-destructive, high spatial resolution investigation tools to study the functional characteristics of the PCC and associate metabolic processes, shows mainly that this is involved in the large scale default mode network (DMN), composed (...)
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  14. Economic Decision-Making in Psychopathy: A Comparison with Ventromedial Prefrontal Lesion Patients.Michael Koenigs, Michael Kruepke & Joseph P. Newman - 2010 - Neuropsychologia 48 (7):2198–2204.
    Psychopathy, which is characterized by a constellation of antisocial behavioral traits, may be subdivided on the basis of etiology: “primary” (low-anxious) psychopathy is viewed as a direct consequence of some core intrinsic deficit, whereas “secondary” (high-anxious) psychopathy is viewed as an indirect consequence of environmental factors or other psychopathology. Theories on the neurobiology of psychopathy have targeted dysfunction within ventromedial prefrontal cortex (vmPFC) as a putative mechanism, yet the relationship between vmPFC function and psychopathy subtype has not been (...)
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  15. Consciousness Despite Network Underconnectivity in Autism: Another Case of Consciousness Without Prefrontal Activity?William Hirstein - 2015 - In Rocco Gennaro (ed.), Disturbed Consciousness: New Essays on Psychopathology and Theories of Consciousness. The M. I. T, Press. pp. 249-263.
    Recent evidence points to widespread underconnectivity in autistic brains owing to deviant white matter, the fibers that make long connections between areas of the cortex. Subjects with autism show measurably fewer long-range connections between the parietal and prefrontal cortices. These findings may help shed light on the current debate in the consciousness literature about whether conscious states require both prefrontal and parietal/temporal components. If it can be shown that people with autism have conscious states despite such underconnectivity, (...)
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  16. The Dark Side of Morality – Neural Mechanisms Underpinning Moral Convictions and Support for Violence.Clifford I. Workman, Keith J. Yoder & Jean Decety - 2020 - American Journal of Bioethics Neuroscience 11 (4):269-284.
    People are motivated by shared social values that, when held with moral conviction, can serve as compelling mandates capable of facilitating support for ideological violence. The current study examined this dark side of morality by identifying specific cognitive and neural mechanisms associated with beliefs about the appropriateness of sociopolitical violence, and determining the extent to which the engagement of these mechanisms was predicted by moral convictions. Participants reported their moral convictions about a variety of sociopolitical issues prior to undergoing functional (...)
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  17. The Neural Correlates of Consciousness.Jorge Morales & Hakwan Lau - 2020 - In Uriah Kriegel (ed.), The Oxford Handbook of the Philosophy of Consciousness. Oxford University Press. pp. 233-260.
    In this chapter, we discuss a selection of current views of the neural correlates of consciousness (NCC). We focus on the different predictions they make, in particular with respect to the role of prefrontal cortex (PFC) during visual experiences, which is an area of critical interest and some source of contention. Our discussion of these views focuses on the level of functional anatomy, rather than at the neuronal circuitry level. We take this approach because we currently understand more (...)
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  18. Pre-Frontal Executive Committee for Perception, Working Memory, Attention, Long-Term Memory, Motor Control, and Thinking: A Tutorial Review.Bill Faw - 2003 - Consciousness and Cognition 12 (1):83-139.
    As an explicit organizing metaphor, memory aid, and conceptual framework, the prefrontal cortex may be viewed as a five-member ‘Executive Committee,’ as the prefrontal-control extensions of five sub-and-posterior-cortical systems: the ‘Perceiver’ is the frontal extension of the ventral perceptual stream which represents the world and self in object coordinates; the ‘Verbalizer’ is the frontal extension of the language stream which represents the world and self in language coordinates; the ‘Motivator’ is the frontal cortical extension of a subcortical (...)
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  19. Conscious Awareness of Retrieval: An Exploration of the Cortical Connectivity.Rajendra D. Badgaiyan - 2005 - International Journal of Psychophysiology 55 (2):257-262.
    A review of the patterns of brain activation observed in implicit and explicit memory tasks indicates that during conscious retrieval studied items are first retrieved nonconsciously and are retained in a buffer at the extrastriate cortex. It also indicates that the awareness of the retrieved item is made possible by the activation of a reentrant signaling loop between the extrastriate and left prefrontal cortices.
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  20. Anesthesia and Consciousess.Rocco J. Gennaro - 2018 - Journal of Cognition and Neuroethics 5 (1):49-69.
    For patients under anesthesia, it is extremely important to be able to ascertain from a scientific, third person point of view to what extent consciousness is correlated with specific areas of brain activity. Errors in accurately determining when a patient is having conscious states, such as conscious perceptions or pains, can have catastrophic results. Here, I argue that the effects of (at least some kinds of) anesthesia lend support to the notion that neither basic sensory areas nor the prefrontal (...)
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  21. Understanding the Higher-Order Approach to Consciousness.Richard Brown, Hakwan Lau & Joseph E. LeDoux - 2019 - Trends in Cognitive Sciences 23 (9):754-768.
    Critics have often misunderstood the higher-order theory (HOT) of consciousness. Here we clarify its position on several issues, and distinguish it from other views such as the global The higher-order theory (HOT) of consciousness has often been misunderstood by critics. Here we clarify its position on several issues, and distinguish it from other views such as the global workspace theory (GWT) and early sensory models (e.g. first-order local recurrency theories). For example, HOT has been criticized for over-intellectualizing consciousness. We show (...)
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  22.  63
    Aesthetics and Morality Judgements Share Functional Neuroarchitecture.Nora Heinzelmann, Susanna Weber & Philippe Tobler - 2020 - Cortex 129:484-495.
    Philosophers have predominantly regarded morality and aesthetics judgments as fundamentally different. However, whether this claim is empirically founded has remained unclear. In a novel task, we measured brain activity of participants judging the aesthetic beauty of artwork or the moral goodness of actions depicted. To control for the content of judgments, participants assessed the age of the artworks and the speed of depicted actions. Univariate analyses revealed whole-brain corrected, content-controlled common activation for aesthetics and morality judgments in frontopolar, dorsomedial and (...)
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  23. Depression and Suicide Are Natural Kinds: Implications for Physician-Assisted Suicide.Jonathan Y. Tsou - 2013 - International Journal of Law and Psychiatry 36 (5-6):461-470.
    In this article, I argue that depression and suicide are natural kinds insofar as they are classes of abnormal behavior underwritten by sets of stable biological mechanisms. In particular, depression and suicide are neurobiological kinds characterized by disturbances in serotonin functioning that affect various brain areas (i.e., the amygdala, anterior cingulate, prefrontal cortex, and hippocampus). The significance of this argument is that the natural (biological) basis of depression and suicide allows for reliable projectable inferences (i.e., predictions) to be (...)
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  24. The Aristotelian Conception of Habit and its Contribution to Human Neuroscience.José Ignacio Murillo & Javier Bernacer - 2014 - Frontiers in Human Neuroscience 8:1-10.
    The notion of habit used in neuroscience is an inheritance from a particular theoretical origin, whose main source is William James. Thus, habits have been characterized as rigid, automatic, unconscious, and opposed to goal-directed actions. This analysis leaves unexplained several aspects of human behavior and cognition where habits are of great importance. We intend to demonstrate the utility that another philosophical conception of habit, the Aristotelian, may have for neuroscientific research. We first summarize the current notion of habit in neuroscience, (...)
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  25. An fMRI Study Measuring Analgesia Enhanced by Religion as a Belief System.Katja Wiech, Miguel Farias, Guy Kahane, Nicholas Shackel, Wiebke Tiede & Irene Tracey - unknown
    Although religious belief is often claimed to help with physical ailments including pain, it is unclear what psychological and neural mechanisms underlie the influence of religious belief on pain. By analogy to other top-down processes of pain modulation we hypothesized that religious belief helps believers reinterpret the emotional significance of pain, leading to emotional detachment from it. Recent findings on emotion regulation support a role for the right ventrolateral prefrontal cortex, a region also important for driving top-down pain (...)
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  26. Mindmelding: Connected Brains and the Problem of Consciousness.William Hirstein - 2008 - Mens Sana Monographs 6 (1):110-130.
    Contrary to the widely-held view that our conscious states are necessarily private (in that only one person can ever experience them directly), in this paper I argue that it is possible for a person to directly experience the conscious states of another. This possibility removes an obstacle to thinking of conscious states as physical, since their apparent privacy makes them different from all other physical states. A separation can be made in the brain between our conscious mental representations and the (...)
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  27. Dynamic Change of Awareness During Meditation Techniques: Neural and Physiological Correlates.Jerath Ravinder, Vernon A. Barnes, David Dillard-Wright, Shivani Jerath & Brittany Hamilton - 2012 - Frontiers in Human Neuroscience 6:1-5.
    Recent fndings illustrate how changes in consciousness accommodated by neural correlates and plasticity of the brain advance a model of perceptual change as a function of meditative practice. During the mindbody response neural correlates of changing awareness illustrate how the autonomic nervous system shifts from a sympathetic dominant to a parasympathetic dominant state. Expansion of awareness during the practice of meditation techniques can be linked to the Default Mode Network (DMN), a network of brain regions that is active when the (...)
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  28.  19
    Brain Electrical Traits of Logical Validity.F. Salto - 2021 - Scientific Reports 11 (7892).
    Neuroscience has studied deductive reasoning over the last 20 years under the assumption that deductive inferences are not only de jure but also de facto distinct from other forms of inference. The objective of this research is to verify if logically valid deductions leave any cerebral electrical trait that is distinct from the trait left by non-valid deductions. 23 subjects with an average age of 20.35 years were registered with MEG and placed into a two conditions paradigm (100 trials for (...)
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  29. The Cartesian Folk Theater: People Conceptualize Consciousness as a Spatio-Temporally Localized Process in the Human Brain.Matthias Forstmann & Pascal Burgmer - forthcoming - Journal of Experimental Psychology: General.
    The present research (total N = 2,057) tested whether people’s folk conception of consciousness aligns with the notion of a “Cartesian Theater” (Dennett, 1991). More precisely, we tested the hypotheses that people believe that consciousness happens in a single, confined area (vs. multiple dispersed areas) in the human brain, and that it (partly) happens after the brain finished analyzing all available information. Further, we investigated how these beliefs arerelated to participants’ neuroscientific knowledge as well as their reliance on intuition, and (...)
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  30.  90
    Juvenile Self-Control and Legal Responsibility: Building a Scalar Standard.Katrina L. Sifferd, Tyler Fagan & William Hirstein - 2020 - In Alfred Mele (ed.), Surrounding Self-Control.
    US criminal courts have recently moved toward seeing juveniles as inherently less culpable than their adult counterparts, influenced by a growing mass of neuroscientific and psychological evidence. In support of this trend, this chapter argues that the criminal law’s notion of responsible agency requires both the cognitive capacity to understand one’s actions and the volitional control to conform one’s actions to legal standards. These capacities require, among other things, a minimal working set of executive functions—a suite of mental processes, mainly (...)
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  31. La hipótesis del marcador somático y la neurobiología de las decisiones.Fabio Morandín-Ahuerma - 2019 - Psycological Writings 12 (1):20-29.
    La hipótesis del marcador somático (SMH) ha sido una de las teorías más influyentes en las neurociencias desde principios de los años 90s en que fue formulada por Antonio Damasio en su libro El error de Descartes (1994). Desde entonces, diversos estudios, a favor y en contra se han escrito, sin un veredicto. En este trabajo se propone una explicación abarcadora de lo que es la hipótesis del marcador somático. En segundo lugar, se hace una valoración sucinta del peso que (...)
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  32.  41
    Processing Emotions - Happiness.Sfetcu Nicolae - manuscript
    According to Antonio Damasio, the emotional process begins with conscious considerations about the object in the form of mental images. These images correspond to a neural substrate (topographic representations) influenced by the dispositional representations. At the unconscious level, the networks in the prefrontal cortex respond automatically and involuntarily to the signals derived from the processing of the above images, according to the dispositional representations, acquired based on personal experience rather than innate. DOI: 10.13140/RG.2.2.21624.06401.
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  33. Associations Between Psychopathic Traits and Brain Activity During Instructed False Responding.Andrea L. Glenn, Hyemin Han, Yaling Yang, Adrian Raine & Robert A. Schug - 2017 - Psychiatry Research: Neuroimaging 266:123-137.
    Lying is one of the characteristic features of psychopathy, and has been recognized in clinical and diagnostic descriptions of the disorder, yet individuals with psychopathic traits have been found to have reduced neural activity in many of the brain regions that are important for lying. In this study, we examine brain activity in sixteen individuals with varying degrees of psychopathic traits during a task in which they are instructed to falsify information or tell the truth about autobiographical and non-autobiographical facts, (...)
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  34.  13
    Heidegger’s Metaphysics, a Theory of Human Perception: Neuroscience Anticipated, Thesis of Violent Man, Doctrine of the Logos.Hermann G. W. Burchard - 2020 - Philosophy Study 10 (11).
    In this essay, our goal is to discover science in Martin Heidegger's Introduction to Metaphysics, lecture notes for his 1935 summer semester course, because, after all, his subject is metaphysica generalis, or ontology, and this could be construed as a theory of the human brain. Here, by means of verbatim quotes from his text, we attempt to show that indeed these lectures can be viewed as suggestion for an objective scientific theory of human perception, the human capacity for deciphering phenomena, (...)
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  35.  42
    Traitement des émotions - Le bonheur.Sfetcu Nicolae - manuscript
    Selon Damasio, le processus émotionnel commence par des considérations conscientes sur l'objet sous forme d'images mentales. Ces images correspondent à un substrat neuronal (représentations topographiques) influencé par les représentations dispositionnelles. Au niveau inconscient, les réseaux du cortex préfrontal répondent automatiquement et involontairement aux signaux issus du traitement des images ci-dessus, selon les représentations dispositionnelles, acquis sur la base d'une expérience personnelle plutôt qu'innée. La réponse est signalée à l'amygdale et au cingulaire antérieur, en activant les noyaux du système nerveux (...)
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  36. Is Cortex Necessary?Sean Allen-Hermanson - 2016 - Animal Sentience 1 (3).
    A key contention of Klein & Barron (2016) is that consciousness does not depend on cortical structures. A critical appraisal suggests they have overestimated the strength of their evidence.
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  37. The Contribution of Prefrontal Executive Processes to Creating a Sense of Self.William Hirstein - 2011 - Mens Sana Monographs 9 (1):150-158.
    According to several current theories, executive processes help achieve various mental actions such as remembering, planning and decision-making, by executing cognitive operations on representations held in consciousness. I plan to argue that these executive processes are partly responsible for our sense of self, because of the way they produce the impression of an active, controlling presence in consciousness. If we examine what philosophers have said about the "ego" (Descartes), "the Self" (Locke and Hume), the "self of all selves" (William James), (...)
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  38. Cortex Excitability, Epilepsy and Brain Illness: Which Are Their Correct Relationships?Massimo Barrella - 2008 - Dialogues in Philosophy, Mental and Neuro Sciences 1 (1):37-39.
    In their work Gilio et al. investigate the mechanisms involved in the regulation of excitability of the cortex in epileptic subjects, and in particular their epileptogenic threshold.
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  39. A Role for the Anterior Insular Cortex in the Global Neuronal Workspace Model of Consciousness.Matthias Michel - 2017 - Consciousness and Cognition 49:333-346.
    According to the global neuronal workspace model of consciousness, consciousness results from the global broadcast of information throughout the brain. The global neuronal workspace is mainly constituted by a fronto-parietal network. The anterior insular cortex is part of this global neuronal workspace, but the function of this region has not yet been defined within the global neuronal workspace model of consciousness. In this review, I hypothesize that the anterior insular cortex implements a cross-modal priority map, the function of (...)
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  40. The Search of “Canonical” Explanations for the Cerebral Cortex.Alessio Plebe - 2018 - History and Philosophy of the Life Sciences 40 (3):40.
    This paper addresses a fundamental line of research in neuroscience: the identification of a putative neural processing core of the cerebral cortex, often claimed to be “canonical”. This “canonical” core would be shared by the entire cortex, and would explain why it is so powerful and diversified in tasks and functions, yet so uniform in architecture. The purpose of this paper is to analyze the search for canonical explanations over the past 40 years, discussing the theoretical frameworks informing (...)
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  41. Modulation of Motor Cortex Activity When Observing Rewarding and Punishing Actions.Elliot Clayton Brown, Jan Roelf Wiersema, Gilles Pourtois & Martin Brüne - 2013 - Neuropsychologia 51 (1):52-58.
    Interpreting others' actions is essential for understanding the intentions and goals in social interactions. Activity in the motor cortex is evoked when we see another person performing actions, which can also be influenced by the intentions and context of the observed action. No study has directly explored the influence of reward and punishment on motor cortex activity when observing others' actions, which is likely to have substantial relevance in different social contexts. In this experiment, EEG was recorded while (...)
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  42. The Life of the Cortical Column: Opening the Domain of Functional Architecture of the Cortex.Haueis Philipp - 2016 - History and Philosophy of the Life Sciences 38 (3).
    The concept of the cortical column refers to vertical cell bands with similar response properties, which were initially observed by Vernon Mountcastle’s mapping of single cell recordings in the cat somatic cortex. It has subsequently guided over 50 years of neuroscientific research, in which fundamental questions about the modularity of the cortex and basic principles of sensory information processing were empirically investigated. Nevertheless, the status of the column remains controversial today, as skeptical commentators proclaim that the vertical cell (...)
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  43.  50
    The Fuzzy Brain. Vagueness and Mapping Connectivity in the Human Cerebral Cortex.Philipp Haueis - 2012 - Frontiers in Neuroanatomy 37 (6).
    While the past century of neuroscientific research has brought considerable progress in defining the boundaries of the human cerebral cortex, there are cases in which the demarcation of one area from another remains fuzzy. Despite the existence of clearly demarcated areas, examples of gradual transitions between areas are known since early cytoarchitectonic studies. Since multi-modal anatomical approaches and functional connectivity studies brought renewed attention to the topic, a better understanding of the theoretical and methodological implications of fuzzy boundaries in (...)
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  44. A Re-Evaluation of Blindsight and the Role of Striate Cortex (V1) in Visual Awareness.Juha Silvanto - 2008 - Neuropsychologia.
    Some patients with a lesion to the striate cortex (V1), when assessed through forced-choice paradigms, are able to detect stimuli presented in the blind field, despite reporting a complete lack of visual experience. This phenomenon, known as blindsight, strongly implicates V1 in visual awareness. However, the view that V1 is indispensable for conscious visual perception is challenged by a recent finding that the blindsight subject GY can be aware of visual qualia in his blind field, implying that V1may not (...)
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  45.  27
    Computational Capacity of Pyramidal Neurons in the Cerebral Cortex.Danko D. Georgiev, Stefan K. Kolev, Eliahu Cohen & James F. Glazebrook - 2020 - Brain Research 1748:147069.
    The electric activities of cortical pyramidal neurons are supported by structurally stable, morphologically complex axo-dendritic trees. Anatomical differences between axons and dendrites in regard to their length or caliber reflect the underlying functional specializations, for input or output of neural information, respectively. For a proper assessment of the computational capacity of pyramidal neurons, we have analyzed an extensive dataset of three-dimensional digital reconstructions from the NeuroMorphoOrg database, and quantified basic dendritic or axonal morphometric measures in different regions and layers of (...)
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  46.  55
    Quantum Propensities in the Brain Cortex and Free Will.Danko D. Georgiev - 2021 - Biosystems 208:104474.
    Capacity of conscious agents to perform genuine choices among future alternatives is a prerequisite for moral responsibility. Determinism that pervades classical physics, however, forbids free will, undermines the foundations of ethics, and precludes meaningful quantification of personal biases. To resolve that impasse, we utilize the characteristic indeterminism of quantum physics and derive a quantitative measure for the amount of free will manifested by the brain cortical network. The interaction between the central nervous system and the surrounding environment is shown to (...)
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  47.  82
    Maternal Exercise During Pregnancy Increases BDNF Levels and Cell Numbers in the Hippocampal Formation but Not in the Cerebral Cortex of Adult Rat Offspring.Sérgio Gomes da Silva - 2016 - PLoS ONE 11 (1):01-15.
    Clinical evidence has shown that physical exercise during pregnancy may alter brain devel- opment and improve cognitive function of offspring. However, the mechanisms through which maternal exercise might promote such effects are not well understood. The present study examined levels of brain-derived neurotrophic factor (BDNF) and absolute cell num- bers in the hippocampal formation and cerebral cortex of rat pups born from mothers exer- cised during pregnancy. Additionally, we evaluated the cognitive abilities of adult offspring in different behavioral paradigms (...)
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  48. From Spinoza to the Socialist Cortex: The Social Brain.Charles T. Wolfe - 2010 - In Deborah Hauptmann & Warren Neidich (eds.), Cognitive Architecture.
    The concept of 'social brain‘ is a hybrid, located somewhere in between politically motivated philosophical speculation about the mind and its place in the social world, and recently emerged inquiries into cognition, selfhood, development, etc., returning to some of the founding insights of social psychology but embedding them in a neuroscientific framework. In this paper I try to reconstruct a philosophical tradition for the social brain, a ‗Spinozist‘ tradition which locates the brain within the broader network of relations, including social (...)
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  49. There but for the Grace of My Orbitofrontal Cortex …. [REVIEW]Frej Klem Thomsen - 2014 - Criminal Justice Ethics 33 (3):220-235.
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  50. What Is Wrong with the No-Report Paradigm and How to Fix It.Ned Block - 2019 - Trends in Cognitive Sciences 23 (12):1003-1013.
    Is consciousness based in prefrontal circuits involved in cognitive processes like thought, reasoning, and memory or, alternatively, is it based in sensory areas in the back of the neocortex? The no-report paradigm has been crucial to this debate because it aims to separate the neural basis of the cognitive processes underlying post-perceptual decision and report from the neural basis of conscious perception itself. However, the no-report paradigm is problematic because, even in the absence of report, subjects might engage in (...)
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