Die Entwicklung von HeImholtz' Mechanismus ist durch einen Wandel im Geltungsanspruch gekennzeichnet und läßt sich in einer noch sehr groben Übersicht in zwei Perioden einteilen. Auf die erste Periode bis etwa zum Ende der 60er Jahre werde ich im ersten Teil meines Beitrages eingehen. Hier rekonstruiere ich umrißhaft die empiristische Begründung, die Helmholtz für den Wahrheitsanspruch seiner Naturauffassung gegeben hat. Im zweiten Teil werde ich dann die wichtigsten Merkmale der im Verlauf der 70er Jahre hervortretenden Hypothetisierungstendenz charakterisieren. Abschliessend will (...) ich in einem dritten Teil zeigen, wie Helmholtz auf der Grundlage seines gewandelten Wissenschaftsverständnisses das Programm einer mechanistischen Naturerklärung mit großem wirkungsgeschichtlichen Einfluß weiter verfolgt hat. (shrink)

Der Verzicht auf absolut gültige Erkenntnis, heute in den Naturwissenschaften beinahe schon selbstverständlich, ist erst jüngeren Datums. Noch im vergangenen Jahrhundert zweifelte die experimentelle Forschung kaum an der vollkommenen Begreifbarkeit der Welt. Diesen Wandel zu erkunden und aufzuzeigen ist Thema der vorliegenden Studie. Der erste Teil präsentiert verschiedene Typen neuzeitlicher und moderner Wissenschaftsauffassungen von Galilei über Newton bis hin zu Kant. Im zweiten Teil werden Entwicklung und Wandel der Wissenschafts- und Naturauffassung bei Helmholtz (1821-1895) erstmals mittels detaillierter Textanalysen einer umfassenden (...) Rekonstruktion unterzogen. Die Relativierung des Wahrheitsanspruchs erlaubt es Helmholtz, seine Naturauffassung trotz der antimechanistischen Kritik innerhalb der Physik, die im letzten Viertel des vergangenen Jahrhunderts laut wurde, als Hypothese aufrechtzuerhalten. Auch gewährt die Studie eine neue Sichtweise des Verhältnisses zwischen Helmholtz und Kant, das in der Vergangenheit kontroverse Beurteilungen erfuhr. (shrink)

Two seemingly contradictory tendencies have accompanied the development of the natural sciences in the past 150 years. On the one hand, the natural sciences have been instrumental in effecting a thoroughgoing transformation of social structures and have made a permanent impact on the conceptual world of human beings. This historical period has, on the other hand, also brought to light the merely hypothetical validity of scientific knowledge. As late as the middle of the 19th century the truth-pathos in the natural (...) sciences was still unbroken. Yet in the succeeding years these claims to certain knowledge underwent a fundamental crisis. For scientists today, of course, the fact that their knowledge can possess only relative validity is a matter of self-evidence. The present analysis investigates the early phase of this fundamental change in the concept of science through an examination of Hermann von Helmholtz's conception of science and his mechanistic interpretation of nature. Helmholtz (1821-1894) was one of the most important natural scientists in Germany. The development of this thoughts offers an impressive but, until now, relatively little considered report from the field of the experimental sciences chronicling the erosion of certainty. (shrink)

Inwieweit vermag sich der ehemalige explanative Erfolg nicht mehr anerkannter Theorien auf die Geltung derjenigen Teilaussagen, die Nachfolgetheorien übernommen haben, zu stützen? Zur Klärung dieser Fragestellung können die Ergebnisse von Machs Untersuchung zur mechanistischen Auffassung des Energieerhaltungssatzes herangezogen werden. Indem er sich in seiner Kritik an den ontologischen Annahmen des Mechanismus auf die Wissenschaftsgeschichte beruft, steht er einer heutigen realismuskritischen Argumentation nahe. Andererseits mißt er den hypothesenfreien Theoriebestandteilen einen Geltungscharakter zu, der in seinem Wahrheitsanspruch durchaus mit einer heutigen realistischen (...) Behauptung theorieübergreifender Bestände der wissenschaftlichen Erkenntnis vergleichbar ist. Daß Mach mit einer quer zur gegenwärtigen Terminologie liegenden Analyse einen Beitrag zur Entschärfung gegenwärtiger Kontroversen leistet, läßt eine erneute Vergegenwärtigung der Schrift von 1872 und den sich daran anschließenden Überlegungen Machs lohnenswert erscheinen. (shrink)

Meine Rekonstruktion von HeImholtz' Begründung der Energieerhaltung beabsichtigt, vor allem das Verhältnis von empirischen und nichtempirischen Elementen aufzuklären. Als erstes möchte ich zeigen, worin die nichtempirischen Elemente bestehen und dass Helmholtz bereits in der Einleitung, wo der selbständige Energiebegriff noch nicht entwickelt ist, an entscheidenden Stellen auf die wissenschaftliche Erfahrung Bezug nimmt. Im Gegensatz zur Transzendentalphilosophie macht Helmholtz die Geltungsbedingungen seines Mechanismus von zukünftigen empirischen Ergebnissen der Wissenschaft abhängig. Er gibt seinem Mechanismus in diesem Zusammenhang eine hypothetische Geltung, (...) an deren bloß vorübergehenden Charakter er aber bemerkenswerterweise keinen Zweifel hegt. (1.) Im zweiten Teil gehe ich der Frage nach, in welchem Maß die mit großer Siegesgewissheit vorgetragene mechanistische Begründung in die Formulierungen des Erhaltungssatzes Eingang findet. Helmholtz verwendet mehrere Energiebegriffe. Haben diese insgesamt oder nur teilweise einen von speziellen naturphilosophischen Annahmen unabhängigen Status? Auf welche Teile der Schrift hätte sich ein Wissenschaftler im vergangenen Jahrhundert stützen können, weIcher von der Energieerhaltung, nicht aber von Helrnholtz' Mechanismus überzeugt gewesen wäre? (2.). (shrink)

Im ersten Teil verorte ich den historischen Kontext des Umbruchprozesses der Wissenschaft des 19. Jahrhunderts im Hinblick auf die Physik. Vom Beginn der Neuzeit bis weit ins 20. Jahrhundert hinein war die Physik die Leitwissenschaft in den Naturwissenschaften. Der Wandlungsprozess der auf sie bezogenen Wissenschaftsauffassungen setzt im 19. Jahrhundert bislang unangetastete, von der Antike herrührende Geltungsansprüche außer Kraft. Im zweiten Teil vergleiche ich Nietzsches Charakterisierung der Wissenschaften exemplarisch mit der von Hermann von Helmholtz. Helmholtz kann als ein herausragender Vertreter der (...) Naturforschung des 19. Jahrhunderts angesehen werden. Er entwickelte seine erste bahnbrechende wissenschaftliche Leistung noch ganz im Rahmen einer auf Wahrheit und Einheit fokussierten Wissenschaftsauffassung. Im Verlauf seiner weiteren Arbeiten relativierten sich seine Geltungsansprüche zunehmend. In systematischer Hinsicht näherte sich Helmholtz damit nicht nur der Position an, die Nietzsche immer schon eingenommen hat, sondern er übertraf sie sogar in bestimmter Hinsicht. -/- Im dritten Teil setze ich mich kritisch mit einem Aspekt der Rezeption des historischen Verhältnisses von Nietzsche und Helmholtz auseinander. Helmholtz gehörte zu den wenigen repräsentativen Naturwissenschaftlern, von denen man annimmt, dass ihre Forschungen auf das Denken Nietzsches Einfluss hatten. Bemerkenswerterweise stammen die betreffenden Arbeiten aus der ersten Phase von Helmholtz’ Wissenschaftsauffassung. Während Helmholtz mit seinen Forschungen einen traditionellen Wahrheitsanspruch bestätigt sah, bezog sich Nietzsche auf sie, um sie umgekehrt zur Destruktion dieses Anspruches einzusetzen. Wo der Rezeption diese Konstellation entgangen ist, hat sie dazu beigetragen, die Aktualität von Nietzsches Wissenschaftskritik zu überschätzen. (shrink)

Hermann von Helmholtz hat als Naturforscher sowohl die Physik als auch die Physiologie um eine beeindruckende Anzahl grundlegender Erkenntnisse bereichert, ihr heutiges Selbstverständnis entscheidend mitgeprägt, ihre Verfahren auf neue Gegenstandsbereiche angewendet und war führend an ihrem institutionellen Ausbau zu Laborwissenschaften beteiligt.

Die von Helmholtz zur Begründung des Energieprinzips in der Einleitung zu seiner Schrift "Über die Erhaltung der Kraft" genannten Bedingungen der physikalischen Forschung teile Ich in zwei Gruppen. Die erste betrifft methodische und begriffliche Voraussetzungen, die zunächst unabhängig von Erfahrung gelten (1); die zweite schränkt diese Geltung ein, indem sie die Reichweite der Methode und die Bestimmung des Ziels der Forschung Erkenntnissen unterordnet, die allein in der Erfahrung gewonnen werden können (2). Nicht den allgemeinen Bedingungen der physikalischen Forschung, sondern speziellen (...) Forschungsergebnissen entnimmt Helmholtz dann die vermeintlichen Hinweise auf die mechanische, d. h. energieerhaltende Struktur der Natur (3). Dieser Argumentation entspricht es. daß er dem physikalischen Naturwissen einen, mit der Zeit abnehmenden hypothetischen Charakter zuweist(4). (shrink)

The ontic conception of scientific explanation has been constructed and motivated on the basis of a putative lexical ambiguity in the term explanation. I raise a puzzle for this ambiguity claim, and then give a deflationary solution under which all ontically-rendered talk of explanation is merely elliptical; what it is elliptical for is a view of scientific explanation that altogether avoids the ontic conception. This result has revisionary consequences for New Mechanists and other philosophers of science, many of whom have (...) assimilated their conception of explanation to the ontic conception. (shrink)

In a recent book and an article, Carl Craver construes the relations between different levels of a mechanism, which he also refers to as constitutive relations, in terms of mutual manipulability (MM). Interpreted metaphysically, MM implies that inter-level relations are symmetrical. MM thus violates one of the main desiderata of scientific explanation, namely explanatory asymmetry. Parts of Craver’s writings suggest a metaphysical interpretation of MM, and Craver explicitly commits to constitutive relationships being symmetrical. The paper furthermore explores the option (...) of interpreting MM epistemologically, as a means for individuating mechanisms. It is argued that MM then is redundant. MM should therefore better be abandoned. (shrink)

We sketch the mechanistic approach to levels, contrast it with other senses of “level,” and explore some of its metaphysical implications. This perspective allows us to articulate what it means for things to be at different levels, to distinguish mechanistic levels from realization relations, and to describe the structure of multilevel explanations, the evidence by which they are evaluated, and the scientific unity that results from them. This approach is not intended to solve all metaphysical problems surrounding physicalism. Yet it (...) provides a framework for thinking about how the macroscopic phenomena of our world are or might be related to its most fundamental entities and activities. (shrink)

When you type the word “serendipity” in a word-processor application such as Microsoft Word, the autocorrection engine suggests you choose other words like “luck” or “fate”. This correcting act turns out to be incorrect. However, it points to the reality that serendipity is not a familiar English word and can be misunderstood easily. Serendipity is a very much scientific concept as it has been found useful in numerous scientific discoveries, pharmaceutical innovations, and numerous humankind’s technical and technological advances. Therefore, there (...) have been many books written around the concept. So why do we need this additional book? This is not just another book about serendipity. It has evolved from the Editor’s question lingering for a decade after finishing his widely cited article (coauthored with Prof. Nancy K. Napier of Boise State University, ID, USA) “Serendipity as a strategic advantage?” in T. Wilkinson’s edited volume Strategic Management in the 21st Century, published by Praeger. The Editor and contributing authors have tried to achieve the following in this title. Demystifying the Serendipity Myth The phenomenon of serendipity has always been thought of as a “miracle”. It is the mystery of human innovation and one of the ultimate secrets of our society. But serendipity is not just a lucky coincidence nor any hidden conspiracy. This book explores the science of the information process behind this seemingly miraculous phenomenon. It connects human society with nature, going back to the root of our existence and looking at the flame of survival to discover the harmony in making creativity. Presenting the nuts and bolts of being an adventurer of science The authors present their conceptual investigations into serendipity’s nature and its mechanism by examining interesting real events and stories. The content is thought-provoking, and readers are led to question and explore their own life stories and problems along the journey of reading this book. Catching an elusive high-value target requires great strategies and efforts. But there are no dark secrets here because this is the “way of nature” – how we humans have always strived for innovation without realizing the blueprints behind such processes. Unlike other books on serendipity, this book will show you that a powerful “secret” is closer than you think. Delivering practical uses for different audiences By understanding the conditionality and survival drivers of serendipity, individuals or organizations can make better decisions on creating the right environment to facilitate the encounter and attainment of this valuable phenomenon. For scientists: With clear explanations of the information processes underlying serendipity, flexible theoretical frameworks of mindsponge and the 3D principle of creativity, researchers are provided with the tools they need to dig deeper into their own fields of study and find practical applications, be it psychology, economics, sociology, or anything that involves innovation (which is, in fact, every scientific discipline). For curious casual readers: Everybody needs innovation to make breakthroughs or spice up one’s life. If you think great ideas come to people randomly from an unknown fairy place, this book will convince you otherwise without taking away that awe and wonder. But above all, you will know how to become more creative, scientifically and straightforwardly, with no snake oil and no weird tricks. For ambitious business people: The flame that brought about great successes throughout human history is within you. But you can only use it if you understand it. While others wait for serendipity to come, you will be able to actively hunt for those precious moments. As it has always been: the best hunters triumph, not the passive wanderers. And in this age of information chaos, finding the golden fruits is not easy. Those from information technology know this problem well, and this book is the treasure map that they have been seeking to navigate that stormy ocean looking for jewels. Like a kingfisher tracking its prey through the water, waiting to gracefully strike, with serendipity, a person seizes the prize of creativity amid the chaos of life. ¤ ¤ ¤ Official introduction: The book explores the nature, underlying causes, and the information processing mechanism of serendipity. It proposes that natural or social survival demands drive serendipity, and serendipity is conditional on the environment and the mindset, on both individual and collective levels. From Darwin's evolution theory to Sun Tzu's war tactics, major innovations throughout human history are unified by this key concept. In the rapidly changing world, information is abundant but rather chaotic. The adaptive power of serendipity allows people to notice treasures within this wild sea, but only for those who understand how it works. To increase the probability of encountering and attaining serendipity, one should employ the mindsponge mechanism and the 3D process of creativity, for without these frameworks, serendipity is truly an elusive target. The book also discusses methods to build environments and cultures rich in navigational and useful information to maximize the chance of finding and capitalizing on serendipity. As a skill, serendipity has a resemblance to how kingfishers observe and hunt their prey. (shrink)

Philosophers of psychology debate, among other things, which psychological models, if any, are (or provide) mechanistic explanations. This should seem a little strange given that there is rough consensus on the following two claims: 1) a mechanism is an organized collection of entities and activities that produces, underlies, or maintains a phenomenon, and 2) a mechanistic explanation describes, represents, or provides information about the mechanism producing, underlying, or maintaining the phenomenon to be explained (i.e. the explanandum phenomenon) (Bechtel (...) and Abrahamsen 2005; Craver 2007). If there is a rough consensus on what mechanisms are and that mechanistic explanations describe, represent, or provide information about them, then how is there no consensus on which psychological models are (or provide) mechanistic explanations? Surely the psychological models that are mechanistic explanations are the models that describe, represent, or provide information about mechanisms. That is true, of course; the trouble arises when determining what exactly that involves. Philosophical disagreement over which psychological models are mechanistic explanations is often disagreement about what it means to describe, represent, or provide information about a mechanism, among other things (Hochstein 2016; Levy 2013). In addition, one's position in this debate depends on a host of other seemingly arcane metaphysical issues, such as the nature of mechanisms, computational and functional properties (Piccinini 2016), and realization (Piccinini and Maley 2014), as well as the relation between models, methodologies, and explanations (Craver 2014; Levy 2013; Zednik 2015). Although I inevitably advocate a position, my primary aim in this chapter is to spell out all these relationships and canvas the positions that have been taken (or could be taken) with respect to mechanistic explanation in psychology, using dynamical systems models and cognitive models (or functional analyses) as examples. (shrink)

The new mechanists and the autonomy approach both aim to account for how biological phenomena are explained. One identifies appeals to how components of a mechanism are organized so that their activities produce a phenomenon. The other directs attention towards the whole organism and focuses on how it achieves self-maintenance. This paper discusses challenges each confronts and how each could benefit from collaboration with the other: the new mechanistic framework can gain by taking into account what happens outside individual (...) mechanisms, while the autonomy approach can ground itself in biological research into how the actual components constituting an autonomous system interact and contribute in different ways to realize and maintain the system. To press the case that these two traditions should be constructively integrated we describe how three recent developments in the autonomy tradition together provide a bridge between the two traditions: (1) a framework of work and constraints, (2) a conception of function grounded in the organization of an autonomous system, and (3) a focus on control. (shrink)

The assumption that psychological states and processes are computational in character pervades much of cognitive science, what many call the computational theory of mind. In addition to occupying a central place in cognitive science, the computational theory of mind has also had a second life supporting “individualism”, the view that psychological states should be taxonomized so as to supervene only on the intrinsic, physical properties of individuals. One response to individualism has been to raise the prospect of “wide computational systems”, (...) in which some computational units are instantiated outside the individual. “Wide computationalism” attempts to sever the link between individualism and computational psychology by enlarging the concept of computation. However, in spite of its potential interest to cognitive science, wide computationalism has received little attention in philosophy of mind and cognitive science. This paper aims to revisit the prospect of wide computationalism. It is argued that by appropriating a mechanistic conception of computation wide computationalism can overcome several issues that plague initial formulations. The aim is to show that cognitive science has overlooked an important and viable option in computational psychology. The paper marshals empirical support and responds to possible objections. (shrink)

I propose a dynamic causal approach to characterizing the notion of a mechanism. Levy and Bechtel, among others, have pointed out several critical limitations of the new mechanical philosophy, and pointed in a new direction to extend this philosophy. Nevertheless, they have not fully fleshed out what that extended philosophy would look like. Based on a closer look at neuroscientific practice, I propose that a mechanism is a dynamic causal system that involves various components interacting, typically nonlinearly, with (...) one another to produce a phenomenon of interest. (shrink)

In some influential histories of ancient philosophy, teleological explanation and mechanistic explanation are assumed to be directly opposed and mutually exclusive alternatives. I contend that this assumption is deeply flawed, and distorts our understanding both of teleological and mechanistic explanation, and of the history of mechanistic philosophy. To prove this point, I shall provide an overview of the first systematic treatise on mechanics, the short and neglected work Mechanical Problems, written either by Aristotle or by a very early member of (...) his school. I will argue that the work is thoroughly Aristotelian in methodology, and that taking it seriously can deepen our understanding of Aristotle’s discussion of animal and human self-motion in the Physics and On the Movement of Animals. (shrink)

In this paper we defend the view that mechanisms are underpinned by networks of difference-making relations. First, we distinguish and criticise two different kinds of arguments in favour of an activity-based understanding of mechanism: Glennan’s metaphysics- first approach and Illari and Williamson’s science-first approach. Second, we present an alternative difference-making view of mechanism and illustrate it by looking at the history of the case of scurvy prevention. We use the case of scurvy to argue that evidence for a (...) mechanism just is evidence for difference-making relations. (shrink)

This paper adds to the philosophical literature on mechanistic explanation by elaborating two related explanatory functions of idealisation in mechanistic models. The first function involves explaining the presence of structural/organizational features of mechanisms by reference to their role as difference-makers for performance requirements. The second involves tracking counterfactual dependency relations between features of mechanisms and features of mechanistic explanandum phenomena. To make these functions salient, we relate our discussion to an exemplar from systems biological research on the mechanism for (...) countering heat shock—the heat shock response system—in Escherichia coli bacteria. This research also reinforces a more general lesson: ontic constraint accounts in the literature on mechanistic explanation provide insufficiently informative normative appraisals of mechanistic models. We close by outlining an alternative view on the explanatory norms governing mechanistic representation. (shrink)

Our perception of where touch occurs on our skin shapes our interactions with the world. Most accounts of cutaneous localisation emphasise spatial transformations from a skin-based reference frame into body-centred and external egocentric coordinates. We investigated another possible method of tactile localisation based on an intrinsic perception of ‘skin space’. The arrangement of cutaneous receptive fields (RFs) could allow one to track a stimulus as it moves across the skin, similarly to the way animals navigate using path integration. We applied (...) curved tactile motions to the hands of human volunteers. Participants identified the location midway between the start and end points of each motion path. Their bisection judgements were systematically biased towards the integrated motion path, consistent with the characteristic inward error that occurs in navigation by path integration. We thus showed that integration of continuous sensory inputs across several tactile RFs provides an intrinsic mechanism for spatial perception. (shrink)

This paper critiques the new mechanistic explanatory program on grounds that, even when applied to the kinds of examples that it was originally designed to treat, it does not distinguish correct explanations from those that blunder. First, I offer a systematization of the explanatory account, one according to which explanations are mechanistic models that satisfy three desiderata: they must 1) represent causal relations, 2) describe the proper parts, and 3) depict the system at the right ‘level.’ Second, I argue that (...) even the most developed attempts to fulfill these desiderata fall short by failing to appropriately constrain explanatorily apt mechanistic models. -/- *This paper used to be called "The Emperor's New Mechanisms". (shrink)

Is the mathematical function being computed by a given physical system determined by the system’s dynamics? This question is at the heart of the indeterminacy of computation phenomenon (Fresco et al. [unpublished]). A paradigmatic example is a conventional electrical AND-gate that is often said to compute conjunction, but it can just as well be used to compute disjunction. Despite the pervasiveness of this phenomenon in physical computational systems, it has been discussed in the philosophical literature only indirectly, mostly with reference (...) to the debate over realism about physical computation and computationalism. A welcome exception is Dewhurst’s ([2018]) recent analysis of computational individuation under the mechanistic framework. He rejects the idea of appealing to semantic properties for determining the computational identity of a physical system. But Dewhurst seems to be too quick to pay the price of giving up the notion of computational equivalence. We aim to show that the mechanist need not pay this price. The mechanistic framework can, in principle, preserve the idea of computational equivalence even between two different enough kinds of physical systems, say, electrical and hydraulic ones. (shrink)

The concept of mechanism in biology has three distinct meanings. It may refer to a philosophical thesis about the nature of life and biology (‘mechanicism’), to the internal workings of a machine-like structure (‘machine mechanism’), or to the causal explanation of a particular phenomenon (‘causal mechanism’). In this paper I trace the conceptual evolution of ‘mechanism’ in the history of biology, and I examine how the three meanings of this term have come to be featured in (...) the philosophy of biology, situating the new ‘mechanismic program’ in this context. I argue that the leading advocates of the mechanismic program (i.e., Craver, Darden, Bechtel, etc.) inadvertently conflate the different senses of ‘mechanism’. Specifically, they all inappropriately endow causal mechanisms with the ontic status of machine mechanisms, and this invariably results in problematic accounts of the role played by mechanism-talk in scientific practice. I suggest that for effective analyses of the concept of mechanism, causal mechanisms need to be distinguished from machine mechanisms, and the new mechanismic program in the philosophy of biology needs to be demarcated from the traditional concerns of mechanistic biology. (shrink)

Philosophers of science have examined The Theory of Island Biogeography by Robert MacArthur and E. O. Wilson (1967) mainly due to its important contribution to modeling in ecology, but they have not examined it as a representative case of ecological explanation. In this paper, I scrutinize the type of explanation used in this paradigmatic work of ecology. I describe the philosophy of science of MacArthur and Wilson and show that it is mechanistic. Based on this account and in light of (...) contributions to the mechanistic conception of explanation due to Craver (2007), and Bechtel and Richardson (1993), I argue that MacArthur and Wilson use a mechanistic approach to explain the species-area relationship. In light of this examination, I formulate a normative account of mechanistic explanation in ecology. Furthermore, I argue that it offers a basis for methodological unification of ecology and solves a dispute on the nature of ecology. Lastly, I show that proposals for a new paradigm of biogeography appear to maintain the norms of mechanistic explanation implicit in The Theory of Island Biogeography. (shrink)

One thing about technical artefacts that needs to be explained is how their physical make-up, or structure, enables them to fulfil the behaviour associated with their function, or, more colloquially, how they work. In this paper I develop an account of such explanations based on the familiar notion of mechanistic explanation. To accomplish this, I outline two explanatory strategies that provide two different types of insight into an artefact’s functioning, and show how human action inevitably plays a role in artefact (...) explanation. I then use my own account to criticize other recent work on mechanistic explanation and conclude with some general implications for the philosophy of explanation.Keywords: Artefact; Technical function; Explanation; Levels of explanation; Mechanisms. (shrink)

Evidence-Based Medicine has little consideration for mechanisms and philosophers of science and medicine have recently made pleas to increase the place of mechanisms in the medical evidence hierarchy. However, in this debate the notions of mechanisms seem to be limited to 'mechanistic processes' and 'complex-systems mechanisms,' understood as 'componential causal systems'. I believe that this will not do full justice to how mechanisms are used in biological, psychological and social sciences and, consequently, in a more biopsychosocial approach to medicine. Here, (...) I propose, following (Kuorikoski, 2009), to pay more attention to 'abstract forms of interaction' mechanisms. The present work scrutinized review articles on depression and medically unexplained pain, which are considered to be of multifactorial pathogenesis, for their use of mechanisms. In review articles on these disorders there seemed to be a range of uses between more 'abstract forms of interaction' and 'componential causal system' mechanisms. I therefore propose to expand the notions of mechanisms considered in medicine to include that of more 'abstract forms of interaction' to better explain and manage biopsychosocial disorders. (shrink)

The central aim of this article is to specify the ontological nature of constitutive mechanistic phenomena. After identifying three criteria of adequacy that any plausible approach to constitutive mechanistic phenomena must satisfy, we present four different suggestions, found in the mechanistic literature, of what mechanistic phenomena might be. We argue that none of these suggestions meets the criteria of adequacy. According to our analysis, constitutive mechanistic phenomena are best understood as what we will call ‘object-involving occurrents’. Furthermore, on the basis (...) of this notion, we will clarify what distinguishes constitutive mechanistic explanations from etiological ones. 1 Introduction 2 Criteria of Adequacy 2.1 Descriptive adequacy 2.2 Constitutive–etiological distinction 2.3 Constitution 3 The Ontological Nature of Constitutive Mechanistic Phenomena 3.1 Phenomena as input–output relations 3.2 Phenomena as end states 3.3 Phenomena as dispositions 3.4 Phenomena as behaviours 4 Phenomena as Object-Involving Occurrents 4.1 What object-involving occurrents are and why we need them 4.2 The object in the phenomenon 4.3 The adequacy of option 5 Conclusion. (shrink)

This paper defines and defends a notion of teleological function which is fit to figure in explanations concerning how organic systems, and the items which compose them, are able to perform certain activities, such as surviving and reproducing or pumping blood. According to this notion, a teleological function of an item (such as the heart) is a typical way in which items of that type contribute to some containing system's ability to do some activity. An account of what it is (...) for an item to contribute to a containing system's ability to perform an activity is provided. I argue that the view acquires its normative status in virtue of the fact that it obeys a function-accident distinction and obeys a function-dysfunction distinction; that the view is ahistorical; and, that its ahistoricity provides it with an advantage over one of its main competitors. (shrink)

During the twentieth century, the mechanistic worldview came under attack mainly because of the rise of quantum mechanics but some of its basic characteristics survived and are still evident within current science in some form or other. Many scholars have produced interesting studies of such significant mechanistic trends within current physics and biology but very few have bothered to explore the effects of this worldview on current chemistry. This paper makes a contribution to fill this gap. It presents first a (...) brief historical overview of the mechanistic worldview and then examines the present situation within chemistry by referring to current studies in the philosophy of chemistry and determining which trends are still mechanistic in spirit and which are not. (shrink)

According to mainstream philosophical views causal explanation in biology and neuroscience is mechanistic. As the term ‘mechanism’ gets regular use in these fields it is unsurprising that philosophers consider it important to scientific explanation. What is surprising is that they consider it the only causal term of importance. This paper provides an analysis of a new causal concept—it examines the cascade concept in science and the causal structure it refers to. I argue that this concept is importantly different from (...) the notion of mechanism and that this difference matters for our understanding of causation and explanation in science. (shrink)

A Kuhnian reformulation of the recent debate in psychiatric nosography suggested that the current psychiatric classification system (the DSM) is in crisis and that a sort of paradigm shift is awaited (Aragona, 2009). Among possible revolutionary alternatives, the proposed fi ve-axes etiopathogenetic taxonomy (Charney et al., 2002) emphasizes the primacy of the genotype over the phenomenological level as the relevant basis for psychiatric nosography. Such a position is along the lines of the micro-reductionist perspective of E. Kandel (1998, 1999), which (...) sees mental disorders reducible to explanations at a fundamental epistemic level of genes and neurotransmitters. This form of micro-reductionism has been criticized as a form of genetic-molecular fundamentalism (e.g. Murphy, 2006) and a multi-level approach, in the form of the burgeoning Cognitive Neuropsychiatry, was proposed. This article focuses on multi-level mechanistic explanations, coming from Cognitive Science, as a possible alternative etiopathogenetic basis for psychiatric classification. The idea of a mechanistic approach to psychiatric taxonomy is here defended on the basis of a better conception of levels and causality. Nevertheless some critical remarks of Mechanism as a psychiatric general view are also offered. (shrink)

This chapter explores a philosophical hypothesis about the nature of (some) probabilities encountered in social sciences. It should be of interest to those with philosophical concerns about the foundations of probability, and to social scientists and philosophers of science who are somewhat puzzled by the nature of probability in social domains. As will become clear below, the chapter is not intended as a contribution to an empirical methodology such as a particular way of applying statistics.

Much contemporary debate on the nature of mechanisms centers on the issue of modulating negative causes. One type of negative causability, which I refer to as “causation by absence,” appears difficult to incorporate into modern accounts of mechanistic explanation. This paper argues that a recent attempt to resolve this problem, proposed by Benjamin Barros, requires improvement as it overlooks the fact that not all absences qualify as sources of mechanism failure. I suggest that there are a number of additional (...) types of effects caused by absences that need to be incorporated to account for the diversity of causal connections in the biological sciences. Furthermore, it is argued that recognizing natural variability in mechanisms, such as attenuation, leads to some interesting line-drawing issues for contemporary philosophy of mechanisms. (shrink)

The Higgs mechanism is an essential but elusive component of the Standard Model of particle physics. Without it Yang‐Mills gauge theories would have been little more than a warm‐up exercise in the attempt to quantize gravity rather than serving as the basis for the Standard Model. This article focuses on two problems related to the Higgs mechanism clearly posed in Earman’s recent papers (Earman 2003, 2004a, 2004b): what is the gauge‐invariant content of the Higgs mechanism, and what (...) does it mean to break a local gauge symmetry? (shrink)

The mindsponge mechanism (mindsponge framework, mindsponge concept, or mindsponge process) provides a way to explain how and why an individual observes and ejects cultural values conditional on the external setting. The term “mindsponge” derives from the metaphor that the mind is analogized to a sponge that squeezes out unsuitable values and absorbs new ones compatible with its core value. Thanks to the complexity and well-structuring, the mechanism has been used to develop various concepts in multiple disciplines.

The causal efficacy of a material system is usually thought to be produced by the law-like actions and interactions of its constituents. Here, a specific system is constructed and explained that produces a cause that cannot be understood in this way, but instead has novel and autonomous efficacy. The construction establishes a proof-of-feasibility of strong emergence. The system works by utilizing randomness in a targeted and cyclical way, and by relying on sustained evolution by natural selection. It is not vulnerable (...) to standard arguments against strong emergence, in particular ones that assume that the physical realm is causally closed. Moreover, it does not suffer from epiphenomenalism or causal overdetermination. The system uses only standard material components and processes, and is fully consistent with naturalism. It is discussed whether the emergent cause can still be viewed as ‘material’ in the way that term is commonly understood. (shrink)

High blood pressure is an important component of pre-eclampsia. The underlying mechanism of development of hypertension in pre-eclampsia is complicated and still remains obscure. Several theories have been advanced including endothelial dysfunction, uteroplacental insufficiency leading to generalized vasoconstriction, increased cardiac output, and sympathetic hyperactivity. Increased blood flow and pressure are thought to lead to capillary dilatation, which damages end-organ sites, leading to hypertension, proteinuria and edema. Additional theories have been put forward based on epidemiological research, implicating immunological and genetic (...) factors. None of these theories have been substantiated. Based on a review of literature this paper postulates that the initiating event for the development of preeclampsia is intermittent hypoxia associated with irregular breathing during sleep, hypoapnea, apnea,inadequate respiratory excursions during the waking hours and inadequate cardiopulmonary synchronization (abnormal sympatho-vagal balance). (shrink)

We humans are natural-born engineers. As such, we model after machines not only isolated, naturally occurring systems, but also the basic laws of physics, sharing with machines a local-evolution-of-state `grammar'. However, previous work by the author casts doubt upon this mechanistic paradigm, suggesting that it is to blame for the stubbornness of many open problems in physics. Simple experiments are therefore proposed to identify `non-machines'. In one experiment, `non mechanistic correlations' in the spirit of Bell are sought in a pair (...) of separated but previously coupled (macroscopic) chaotic systems. In another it is tested whether chaotic systems could fuzzily `remember their future' in the sense that a future binary perturbation applied to them could be inferred from their present behavior with probability$>1/2$. Chaotic systems are chosen as candidates because the long-time application of their (deterministic) mechanistic description is conceptually groundless: All scales are significant and mutually coupled in that regime, down to scales governed by QM, yet the quantum-classical transition remains inexplicable---if only due to the measurement problem. Similarly for non-deterministic chaotic systems, modeled as such purely for defying a short-time deterministic mechanistic description. Should a non mechanistic signature be found in such simple systems, the implications for science as a whole and life sciences in particular cannot be overstated. (shrink)

The use of neuroscientific evidence in criminal trials has been steadily increasing. Despite progress made in recent decades in understanding the mechanisms of psychological and behavioral functioning, neuroscience is still in an early stage of development and its potential for influencing legal decision-making is highly contentious. Scholars disagree about whether or how neuroscientific evidence might impact prescriptions of criminal culpability, particularly in instances in which evidence of an accused’s history of mental illness or brain abnormality is offered to support a (...) plea of not criminally responsible. In the context of these debates, philosophers and legal scholars have identified numerous problems with admitting neuroscientific evidence in legal contexts. To date, however, less has been said about the challenges of evaluating the evidence upon which integrative mechanistic explanations that bring together evidence from different areas of neuroscience are based. As we explain, current criteria for evaluating such evidence to determine its admissibility in legal contexts are inadequate. Appealing to literature in the philosophy of scientific experimentation and theoretical work in the social, cognitive and behavioral sciences, we lay the groundwork for reforming these criteria and identify some of the implications of modifying them. (shrink)

This paper advances the thesis of methodological mechanism, the claim that to be committed to mechanism is to adopt a certain methodological postulate, i.e. to look for causal pathways for the phenomena of interest. We argue that methodological mechanism incorporates a minimal account of understanding mechanisms, according to which a mechanism just is a causal pathway described in the language of theory. In order to argue for this position we discuss a central example of a biological (...) mechanism, the mechanism of cell death, known as apoptosis. We argue that this example shows that our philosophically deflationary account is sufficient in order to have an illuminating account of mechanisms as the concept is used in biology. (shrink)

There is, of course, The Given: what is given in experience. The ‘Myth Of The Given’ is just a wrong answer to the question ‘What is given?’ This paper offers a brief sketch of three possible right answers. It examines an early account by Charles Augustus Strong of why The Myth is a myth. It maintains that a natural and naturalistic version of empiricism is compatible with the fact that the Myth is a myth. It gives proper place to enactivist (...) considerations. It is ) broadly in line with the Sellarsian view as refined by John McDowell. It meets an important constraint: acknowledging the reality of something that seems at first to lend support to The Myth—i.e. the fact that we can engage in ‘non-inferential self-attribution of … sensations’ —without in any way succumbing to the Myth. (shrink)

Problem Statement. The process of global evolution has entered the Anthropocene. This fact has almost simultaneously generated two cardinal, inseparable imperatives in the rapidly changing ideological and outlook basis of modern civilization. Firstly, the feeling that the new geological epoch also requires fundamentally new algorithms guiding practical activity and its theoretical comprehension, justification in all spheres of political reality, with inevitable exit to the level of international relations and geopolitics. Secondly, the content of the categories of ANTHROPOCEN and (GLOBAL) CRISIS (...) overlap so diversely and widely that they form an almost inseparable logically and mentally amalgam. The purpose of this publication is to reveal the political aspects of the integration of new biopolitical issues into the life of modern society. The content of the term biopolitics is currently not formalized in a definitive form. In our concept, biopolitics is defined as the processes of implementing biopower, that is, the ability (direct or indirect) of the power structures of society to control and manipulate the performance of the biological functions of certain individuals. Based on a combination of methods of conceptual, discursive and evolutionary-anthropological analysis (the concepts of evolutionary strategy and cultural-ecological niche), possible scenarios for the future development of the political process at the domestic and international levels are identified. The mechanism of transbipolitical transition – the inclusion of civilizational and biological evolution in the political process – is investigated. The conclusion formulates the content of the category “transbiolitics” as the main element of rationalization of the global-evolutionary process in the globalizing world. Transbiolitics in our understanding is an international political problematic related to the rationalization of the global evolutionary process. Technologization of the global evolutionary process, the choice of implemented technological projects and forms of their institutional support is determined primarily by geo- and biopolitical motivation of local elites and humanitarian and other convergent technologies available to them. (shrink)

Most defenders of the new mechanistic approach accept ontic constraints for successful scientific explanation (Illari 2013; Craver 2014). The minimal claim is that scientific explanations have objective truthmakers, namely mechanisms that exist in the physical world independently of any observer and that cause or constitute the phenomena-to- be-explained. How can this idea be applied to type-level explanations? Many authors at least implicitly assume that in order for mechanisms to be the truthmakers of type-level explanation they need to be regular (Andersen (...) 2012; Sheredos 2015). One problem of this assumption is that most mechanisms are (highly) stochastic in the sense that they “fail more often than they succeed” (Bogen 2005; Andersen 2012). How can a mechanism type whose instances are more likely not to produce an instance of a particular phenomenon type be the truthmaker of the explanation of that particular phenomenon type? In this paper, I will give an answer to this question. I will analyze the notion of regularity and I will discuss Andersen's suggestion for how to cope with stochastic mechanisms. I will argue that her suggestion cannot account for all kinds of stochastic mechanisms and does not provide an answer as to why regularity grounds type-level explanation. According to my analysis, a mechanistic type- level explanation is true if and only if at least one of the following two conditions is satisfied: the mechanism brings about the phenomenon more often than any other phenomenon (comparative regularity) or the phenomenon is more often brought about by the mechanism than by any other mechanism/causal sequence (comparative reverse regularity). (shrink)

This article presents a distinct sense of ‘mechanism’, which I call the functional sense of mechanism. According to this sense, mechanisms serve functions, and this fact places substantive restrictions on the kinds of system activities ‘for which’ there can be a mechanism. On this view, there are no mechanisms for pathology; pathologies result from disrupting mechanisms for functions. Second, on this sense, natural selection is probably not a mechanism for evolution because it does not serve a (...) function. After distinguishing this sense fromsimilar explications of ‘mechanism’, I argue that it is ubiquitous in biology and has valuable epistemic benefits. (shrink)

While ideal interventions are acknowledged by many as valuable tools for the analysis of causation, recent discussions have shown that, since there are no ideal interventions on upper-level phenomena that non-reductively supervene on their underlying mechanisms, interventions cannot—contrary to a popular opinion—ground an informative analysis of constitution. This has led some to abandon the project of analyzing constitution in interventionist terms. By contrast, this paper defines the notion of a horizontally surgical intervention, and argues that, when combined with some innocuous (...) metaphysical principles about the relation between upper and lower levels of mechanisms, that notion delivers a sufficient condition for constitution. This, in turn, strengthens the case for an interventionist analysis of constitution. (shrink)

Tantra means knowledge of methodical and mechanical investigational-technique through which we develop our consciousness and faculties of consciousness. It is also a process through which we can able to be realized our inherent spiritual powers. The term “Tantra” has been derived from the Sanskrit term “Tan” which means to “Magnify” or to “Outspread”. People use Tantra in a very mechanical way to transform their personality from animalhood to divinity. Basically, in the school of Buddhism, Tantra has developed a system of (...) thought which makes us see the universe as if it were within ourselves, and ourselves as if we were within the universe. In addition, we can argue that the forces governing the cosmos on the macro-level are believed to govern the individual in the micro-level. According to Tantra, there is a pyramid among individual being and universal being rather both sides are same. Thus all that exists in the universe must also exist in the individual body. It means we are all one under the umbrella of the sky. According to Buddhism, Tantra is the best way to salvation. Because, through the mechanism of Tantra, people can overcome to ignorance and affection towards the material world and can achieve wisdom. (shrink)

Though the realm of biology has long been under the philosophical rule of the mechanistic magisterium, recent years have seen a surprisingly steady rise in the usurping prowess of process ontology. According to its proponents, theoretical advances in the contemporary science of evo-devo have afforded that ontology a particularly powerful claim to the throne: in that increasingly empirically confirmed discipline, emergently autonomous, higher-order entities are the reigning explanantia. If we are to accept the election of evo-devo as our best conceptualisation (...) of the biological realm with metaphysical rigour, must we depose our mechanistic ontology for failing to properly “carve at the joints” of organisms? In this paper, I challenge the legitimacy of that claim: not only can the theoretical benefits offered by a process ontology be had without it, they cannot be sufficiently grounded without the metaphysical underpinning of the very mechanisms which processes purport to replace. The biological realm, I argue, remains one best understood as under the governance of mechanistic principles. (shrink)