Results for 'antibodies'

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  1. The ImmPort Antibody Ontology.William Duncan, Travis Allen, Jonathan Bona, Olivia Helfer, Barry Smith, Alan Ruttenberg & Alexander D. Diehl - 2016 - Proceedings of the International Conference on Biological Ontology 1747.
    Monoclonal antibodies are essential biomedical research and clinical reagents that are produced by companies and research laboratories. The NIAID ImmPort (Immunology Database and Analysis Portal) resource provides a long-term, sustainable data warehouse for immunological data generated by NIAID, DAIT and DMID funded investigators for data archiving and re-use. A variety of immunological data is generated using techniques that rely upon monoclonal antibody reagents, including flow cytometry, immunofluorescence, and ELISA. In order to facilitate querying, integration, and reuse of data, standardized (...)
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  2. Immunoglobulins and Antibodies: Conceptual Projections All the Way Down.Bartlomiej Swiatczak - 2022 - Constructivist Foundations 18 (1):85-86.
    Central to vaccination-induced responses, antibodies are suggested by Vaz to operate as observer-dependent entities that owe their status to categorization schemes of immunologists. Inspired by color research by Maturana, he argues that antibodies should be distinguished from immunoglobulins, which unlike the former can be considered as constituents of structural dynamics of an organism, products of millions of years of evolution. However, a deeper understanding of the historical roots of the concept of immunoglobulin and associated “languaging” and naming processes (...)
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  3. Anti-phospholipase A2 Receptor Antibody Measurement in Patients with Idiopathic Membranous Nephropathy Diagnosed by Renal Biopsy.Sadettin Öztürk, Ozlem Usalan, Celalettin Usalan & Orhan Ozdemir - 2023 - European Journal of Therapeutics 29 (2):116-122.
    Objective: Our study is a cross-sectional study that aims to evaluate the presence and levels of anti-phospholipase A2 receptor (PLA2R) antibodies in healthy volunteers and idiopathic membranous nephropathy (IMN) patients and to assess the relationship between these levels and clinical parameters. -/- Methods: Serum anti-PLA2R antibody levels, complete blood count, urea, creatinine (Kre), total protein,albumin, low-density lipoprotein (LDL)-cholesterol, triglycerides (TG), high-density lipoprotein (HDL)-cholesterol, total cholesterol, C-reactive protein (crp), sedimentation, proteinuria were measured from 71 IMN patients and 48 healthy volunteers. (...)
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  4. COVID-19 Adaptive Humoral Immunity Models: Weakly Neutralizing Versus Antibody-Disease Enhancement Scenarios.Ghozlane Yahiaoui, Gabriel Turinici, Oriane Pagani-Azizi & Antoine Danchin - 2022 - Acta Biotheoretica 70 (4):23.
    The interplay between the virus, infected cells and immune responses to SARS-CoV-2 is still under debate. By extending the basic model of viral dynamics, we propose here a formal approach to describe neutralisation versus weak (or non-)neutralisation scenarios and compare them with the possible effects of antibody-dependent enhancement (ADE). The theoretical model is consistent with the data available in the literature; we show that both weakly neutralising antibodies and ADE can result in final viral clearance or disease progression, but (...)
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  5. Why Can't I feel My Feet? : Antibodies Playing on the Nerve Floor.Debprasad Dutta - 2020 - In R. Sharma, B. K. Tyagi, K. B. Bhushan, G. Jain & Avilekh N. (eds.), AWSAR Awarded Popular Science Stories: by Scientists for the People. Vigyan Prasar. pp. 335-338.
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  6. Lara V. Marks. The Lock and Key of Medicine: Monoclonal Antibodies and the Transformation of Healthcare. xxv + 316 pp., illus., figs., tables, bibl., index. New Haven, Conn./London: Yale University Press, 2015. $40. [REVIEW]Buhm Soon Park - 2017 - Isis 108 (3):746-747.
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  7. Fair allocation of scarce therapies for COVID-19.Govind Persad, Monica E. Peek & Seema K. Shah - 2021 - Clinical Infectious Diseases 18:ciab1039.
    The U.S. FDA has issued emergency use authorizations for monoclonal antibodies for non-hospitalized patients with mild or moderate COVID-19 disease and for individuals exposed to COVID-19 as post-exposure prophylaxis. One EUA for an oral antiviral drug, molnupiravir, has also been recommended by FDA’s Antimicrobial Drugs Advisory Committee, and others appear likely in the near future. Due to increased demand because of the Delta variant, the federal government resumed control over the supply and asked states to ration doses. As future (...)
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  8. A Multicenter Weighted Lottery to Equitably Allocate Scarce COVID-19 Therapeutics.D. B. White, E. K. McCreary, C. H. Chang, M. Schmidhofer, J. R. Bariola, N. N. Jonassaint, Parag A. Pathak, G. Persad, R. D. Truog, T. Sonmez & M. Utku Unver - 2022 - American Journal of Respiratory and Critical Care Medicine 206 (4):503–506.
    Shortages of new therapeutics to treat coronavirus disease (COVID-19) have forced clinicians, public health officials, and health systems to grapple with difficult questions about how to fairly allocate potentially life-saving treatments when there are not enough for all patients in need (1). Shortages have occurred with remdesivir, tocilizumab, monoclonal antibodies, and the oral antiviral Paxlovid (2) -/- Ensuring equitable allocation is especially important in light of the disproportionate burden experienced during the COVID-19 pandemic by disadvantaged groups, including Black, Hispanic/Latino (...)
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  9. Sero-Epidemiological Study of Respiratory Syncytial Virus.Mami Niida, Tetsuo Nakayama & Eitaro Suzuki - manuscript
    Background: Respiratory syncytial virus (RSV) is one of the major viruses that cause respiratory infections in all generations, not only in neonates and infants. There is a limited number of reports on serological epidemiology of RSV subgroups A and B. Neutralizing test (NT) antibody reflects protective immunity but bothersome. Sero-epidemiological study should be performed using practical NT method. Methods: Two wild-type viruses subgroups A and B, isolated in 2013, and the Long strain was used as the challenge viruses. NT antibody (...)
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  10. Serum lmmunglobulin and Complement Levels in the Patients With Head and Neck Carcinoma and the Evaluation of Autoantibody Positivity Rate.Sabri Güngör, Hüseyin Gün & Yalçın Özkaptan - 1990 - European Journal of Therapeutics 1 (1):4-12.
    Serum lmmunglobulin and Complement Levels in the Patients With Head and Neck Carcinoma and the Evaluation of Autoantibody Positivity Ratein this study, smooth muscle antibody (SMA), anti-nücleer antibody (ANA) anti- mitochondrial antibody (AMA), anti-parietal cell antibody (PA), antiglomerular basal membrane antibody (GM), serum immunglobulins and complement-C3 levels have been searched. The positivity rate of ANA (31.91 %) and SMA (38.29 %) were found high in sera of the patients with head and neck carcinoma which had been diagnosed histopathologically. But the (...)
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  11. The case of psoriatic arthritis developed periorbital infection following adalimumab therapy.Tuba Tülay Koca & Gülbahar Saraç - 2014 - European Journal of Therapeutics 20 (4):323-327.
    Psoriatic arthritis is a chronic, systemic inflammatory disorder. It has been classified in spondyloarthropathies group which shares clinical, radiologic, serologic features, familial and genetic relationship. Up to 5-30% of patients with psoriasis may go on to develop psoriatic arthritis, usually within 5-10 years. Adalimumab (ADA) is the first human monoclonal antibody against TNF-α. ADA is a biologic agent effective in both skin lesions and joint signs. Anti-TNF agents are powerful immunmodulating drugs with potentially side effects. Our case is 38 years (...)
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  12. Hashimoto’s Thyroiditis is Not a Negative Contributor to Papillary Thyroid Cancer.Zeynep Çetin, Özden Başer & Serdar Güler - 2022 - European Journal of Therapeutics 28 (1):30-36.
    Objective: Hashimoto’s thyroiditis is the most common autoimmune thyroid disease. Papillary thyroid cancer is the most common thyroid cancer. Whether Hashimoto’s thyroiditis is a predisposing factor for papillary thyroid cancer remains unclear. In this study, the frequency of papillary thyroid cancer was investigated in patients with Hashimoto’s thyroiditis who underwent total thyroidectomy. -/- Methods: In this study, 534 patients were screened retrospectively. Preoperative thyroid function tests, anti-thyroid antibodies, ultrasonography findings, fine-needle aspiration biopsies, and thyroidectomy pathology results were examined. According (...)
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  13. COVID-19 Pandemic: Evidences from Clinical Studies.Ravi Shankar Singh, Abhishek Kumar Singh, Kamla Kant Shukla & Amit Kumar Tripathi - 2020 - Journal of Community and Public Health Nursing 6 (4):251.
    The public health crisis is started with emergence of new coronavirus on 11 February 2020 which triggered as coronavirus disease-2019 (COVID-19) pandemics. The causative agent in COVID-19 is made up of positively wrapped single-stranded RNA viruses ~ 30 kb in size. The epidemiology, clinical features, pathophysiology, and mode of transmission have been documented well in many studies, with additional clinical trials are running for several antiviral agents. The spreading potential of COVID-19 is faster than its two previous families, the severe (...)
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  14. Considerações legais e forenses do aborto infeccioso bovino na “Saúde Única”: Revisão (18th edition).Jackson Barros Do Amaral, Vinícius José Moreira Nogueira & Wendell da Luz Silva (eds.) - 2024 - Londrina: Pubvet.
    In Brazil, the social demand for veterinary expertise is growing. However, there is still a shortage of professionals trained in this area to apply specific knowledge to each case. Studies and research into forensic veterinary medicine are necessary for veterinary experts to assist in investigations and legal proceedings. Veterinary medicine has subjects on its curriculum that cover the knowledge needed to apply in the fields of animal health, public health and the environment. The interaction between human and veterinary medicine, as (...)
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