Computational reproducibility possesses its own dynamics and narratives of crisis. Alongside the difficulties of computing as an ubiquitous yet complex scientific activity, computational reproducibility suffers from a naive expectancy of total reproducibility and a moral imperative to embrace the principles of free software as a non-negotiable epistemic virtue. We argue that the epistemic issues at stake in actual practices of computational reproducibility are best unveiled by focusing on software as a pivotal concept, one that is surprisingly (...) often overlooked in accounts of reproducibility issues. Software is not only about designing and coding but also about maintaining, supporting, distributing, licensing, and governance; it is not only about developers but also about users. We focus on openness debates among computational chemists involved in molecular modeling software packages as empirical grounding for our argument. We then identify and analyse four epistemic characteristics as key to the role of software in computational reproducibility. (shrink)

Replicability and reproducibility of computational models has been somewhat understudied by “the replication movement.” In this paper, we draw on methodological studies into the replicability of psychological experiments and on the mechanistic account of explanation to analyze the functions of model replications and model reproductions in computational neuroscience. We contend that model replicability, or independent researchers' ability to obtain the same output using original code and data, and model reproducibility, or independent researchers' ability to recreate a model without (...) original code, serve different functions and fail for different reasons. This means that measures designed to improve model replicability may not enhance (and, in some cases, may actually damage) model reproducibility. We claim that although both are undesirable, low model reproducibility poses more of a threat to long-term scientific progress than low model replicability. In our opinion, low model reproducibility stems mostly from authors' omitting to provide crucial information in scientific papers and we stress that sharing all computer code and data is not a solution. Reports of computational studies should remain selective and include all and only relevant bits of code. (shrink)

Estudo comparado sobre o tratamento dado à reprodução humana assistida no direito do Brasil, Estados Unidos, Portugal, Espanha e Itália.

Friedrich Engels’ dialectical assessment of modern science resulted from his fascination with the natural sciences in combination with his resurging interest in the work of “old Hegel.” Engels became especially interested in what he saw as the molecular essence of life, namely proteins or, more specifically, albumin, seeing life as the mode of existence of these enigmatic substances. Hegelian dialectics is crucial for a dialectical materialist understanding of contemporary technoscience. The dialectical materialist understanding of technoscience as a research practice builds (...) on Engels, but also on later authors who were inspired by his writings, e.g., life scientists such as Haldane and Bernal. Considering the criticism raised against Engels’ dialectics by 20th-century Marxists, a dialectical diagnostic of contemporary technoscience can be achieved, which shifts the focus from artificial albumin as “living matter” to contemporary research on synthetic cells. (shrink)

Walter Benjamin’s oft-quoted 1936 essay “The Work of Art in the Age of Its Technological Reproducibility” advances the claim that, for the first time in history, the “function” of the work of art is political, as evidenced by cinema. For Benjamin, film is the “first art form whose artistic character is entirely determined by its reproducibility” and Giorgio Agamben, a contemporary Benjaminian philosopher, further elucidates this “function,” positing that cinema essentially ranks with ethics and politics, not solely with (...) aesthetics, and, consequently, is proximate to philosophy itself. Whereas Deleuze’s Cinema books posed cinema as enacting time in a pure state, Agamben, in his “Notes on Gesture,” breaches from Deleuze’s spatial and cartographic theory of cinema, drawing on Guy Debord’s “détournement via montage,” Simone Weil’s “decreation” and, perhaps most implicitly, from Benjamin. Agamben’s political theory of cinema, motivated by cinema’s “stoppage and repetition of time,” is directly informed by Benjamin’s: “optical unconscious,” appropriation of Brecht’s “social Gestus,” and the relationship between technological reproducibility and aura. Agamben’s “gesture” fastens cinema’s aesthetics not only to ethics and politics, but to the “ontological consistency of human experience,” or to a way of being. (shrink)

Recent philosophical work has praised the reward structure of science, while recent empirical work has shown that many scientific results may not be reproducible. I argue that the reward structure of science incentivizes scientists to focus on speed and impact at the expense of the reproducibility of their work, thus contributing to the so-called reproducibility crisis. I use a rational choice model to identify a set of sufficient conditions for this problem to arise, and I argue that these (...) conditions plausibly apply to a wide range of research situations. Currently proposed solutions will not fully address this problem. Philosophical commentators should temper their optimism about the reward structure of science. (shrink)

Human reproduction has long been assumed to be an act of the blind force of nature, to which humans were subject, like the weather. However, with recent concerns about the environmental impact of human population, particularly resource depletion, human reproduction has come to be seen as a moral issue. That is, in general, it may be moral or immoral for people to continue propagating their species. The past decade’s philosophical discussions of the question have yielded varying results. This dissertation takes (...) on the issue in a broader moral perspective and asks not only whether it is moral to reproduce but why one should. That is, are there positive normative reasons, whether moral or rational, to reproduce? This thesis approaches this problem first by facing three general philosophical challenges to its resolution: from contemporary population and environmental ethics and rationality theory; from traditional Western schools of moral philosophy; and from recent attempts to answer the narrower question of whether one should reproduce. The thesis finds that exploring these challenges cannot yield a clear response. However, taking cues from many of these approaches, such as care ethics’ emphasis on values, the dissertation proposes that lacking from recent attempts is recognition of a source-value for all human values, viz. the valuing of life in and of itself. Proposing that this valuing is a characteristic of humans and of how they value, it looks to anthropology for empirical justification. It observes that many cultures and individuals frequently prioritize their values so as to devalue this source valuing. Yet, when those value prioritizations give this valuing high priority, there may be some moral justification for reproduction. Furthermore, if one subscribes to the tenets of rationality, which enjoin agents to formulate their beliefs for action based upon the results of rational inquiry, this normative force may invest this descriptive (empirical) hypothesis about values with normative force to guide actions. That is, given certain value prioritizations, it may be rational as well as moral to reproduce. The thesis question of why one should reproduce would then at least have a plausible answer. (shrink)

Statistics play a critical role in biological and clinical research. However, most reports of scientific results in the published literature make it difficult for the reader to reproduce the statistical analyses performed in achieving those results because they provide inadequate documentation of the statistical tests and algorithms applied. The Ontology of Biological and Clinical Statistics (OBCS) is put forward here as a step towards solving this problem. Terms in OBCS, including ‘data collection’, ‘data transformation in statistics’, ‘data visualization’, ‘statistical data (...) analysis’, and ‘drawing a conclusion based on data’, cover the major types of statistical processes used in basic biological research and clinical outcome studies. OBCS is aligned with the Basic Formal Ontology (BFO) and extends the Ontology of Biomedical Investigations (OBI), an OBO (Open Biological and Biomedical Ontologies) Foundry ontology supported by over 20 research communities. We discuss two examples illustrating how the ontology is being applied. In the first (biological) use case, we describe how OBCS was applied to represent the high throughput microarray data analysis of immunological transcriptional profiles in human subjects vaccinated with an influenza vaccine. In the second (clinical outcomes) use case, we applied OBCS to represent the processing of electronic health care data to determine the associations between hospital staffing levels and patient mortality. Our case studies were designed to show how OBCS can be used for the consistent representation of statistical analysis pipelines under two different research paradigms. By representing statistics-related terms and their relations in a rigorous fashion, OBCS facilitates standard data analysis and integration, and supports reproducible biological and clinical research. (shrink)

Being born into a family structure—being born of a mother—is key to being human. It is, for Jacques Lacan, essential to the formation of human desire. It is also part of the structure of analogy in the Thomistic thought of Erich Przywara. AI may well increase exponentially in sophistication, and even achieve human-like qualities; but it will only ever form an imaginary mirroring of genuine human persons—an imitation that is in fact morbid and dehumanising. Taking Lacan and Przywara at a (...) point of convergence on this topic offers important insight into human exceptionalism. (shrink)

Dubljević and company’s proposed approach for incorporating a socio-political perspective into neuroethics has clear potential to help mitigate the effects of research ‘hype’ relating to neuroethics. Their approach serves as a social regulation meant to improve the realizability of neuroethics research. Drawing on Dubljević et al. s suggestion, we consider how incorporating a socio-political perspective in other scientific disciplines could help the scientific community as a whole move beyond the infamous ‘reproducibility crisis’ in science. The reproducibility crisis is (...) a concern in science stemming from the revelation that most scientific results are difficult, or impossible, to replicate (Frias-Navarro et al., 2020). By applying the four principles proposed by Dubljević et al., the scientific community can avoid many of the pitfalls that have led to the reproducibility crisis, such as the file drawer effect, a publication bias preventing negative results from being published, or the publish-or-perish culture - the pressure for scientists to publish highly influential papers in high impact journals in order to keep their funding (Rosenthal, 1979; Begley & Ioannidis, 2015). As such, we argue that, in its final form, this socio-political framework begs for true open science, wherein systematically sharing data would enable enlightened policymaking by showing a picture closer to the ground-level realities of scientific research. (shrink)

Benjamin's The Work of Art in the Age of Its Technological Reproducibility, and Other Writings on Media .

For the last ten years, within molecular life sciences, the reproducibility crisis discourse has been embodied as a crisis of trust in scientific images. Beyond the contentious perception of “questionable research practices” associated with a digital turn in the production of images, this paper highlights the transformations of gel electrophoresis as a family of experimental techniques. Our aim is to analyze the evolving epistemic status of generated images and its connection with a crisis of trust in images within that (...) field.From the 1980s to the 2000s, we identify two key innovations (precast gels and gel docs) leading to a “two‐tiered” gel electrophoresis with different standardization procedures, different epistemic statuses of the produced images and different ways of generating (dis)trust in images. The first tier, exemplified by differential gel electrophoresis (DIGE), is characterized by specialized devices processing images as quantitative data. The second tier, exemplified by polyacrylamide gel electrophoresis (PAGE), is described as a routine technique making use of image as qualitative “virtual witnessing.” The difference between these two tiers is particularly apparent in the ways images are processed, even though both tiers involve image digitization. Our account thus highlights different views on reproducibility within the two tiers. Comparability of images is insisted upon in the first tier while traceability is expected in the second tier. It is striking that these differences occur not only within the same scientific field, but even within the same family of experimental techniques. In the second tier, digitization entails distrust, whereas it implies a collective sentiment of trust in the first tier. (shrink)

This paper examines a looming reproducibility crisis in the core of the hard sciences. Namely, it concentrates on molecular modeling and simulation (MMS), a family of methods that predict properties of substances through computing interactions on a molecular level and that is widely popular in physics, chemistry, materials science, and engineering. The paper argues that in order to make quantitative predictions, sophisticated models are needed which have to be evaluated with complex simulation procedures that amalgamate theoretical, technological, and social (...) factors – leading to problems with reproducibility. Thus, for methodological reasons, the predictive success causes a reproducibility problem. (shrink)

I present and defend the generalized selected effects theory (GSE) of function. According to GSE, the function of a trait consists in the activity that contributed to its bearer’s differential reproduction, or differential retention, within a population. Unlike the traditional selected effects (SE) theory, it does not require that the functional trait helped its bearer reproduce; differential retention is enough. Although the core theory has been presented previously, I go significantly beyond those presentations by providing a new argument for GSE (...) and defending it from a recent objection. I also sketch its implications for teleosemantics and philosophy of medicine. (shrink)

This essay hypothesizes that the Universe contains a self-reproducing neural network of Black Holes with computational abilities—i.e., the Universe can “think”! It then rephrases the Final Anthropic Principle to state: “Intelligent information-processing must come into existence in each new Universe to assure the birth of intelligent successor universes”. Continued research into the theory of Early Universe and Black Hole information storage, processing and retrieval is recommended, as are observational searches for time-correlated electromagnetic and gravitational wave emission patterns from widely separated (...) Black Hole transient events indicative of the existence of a universal inter-Black Hole faster-than-light communications network. (shrink)

Given the reproducibility crisis (or replication crisis), more psychologists and social-cultural scientists are getting involved with Bayesian inference. Therefore, the current article provides a brief overview of programs (or software) and steps to conduct Bayesian data analysis in social sciences.

Vardoulakis examines the connection between the political and aesthetic commitments of the philosophies of Martin Heidegger and Walter Benjamin. He compares "The Origin of the Work of Art" to "The Work of Art in the Age of Technological Reproducibility.".

Resumo A transferência de embriões em bovinos tem o objetivo principal de aprimorar o melhoramento genético e otimizar a reprodução bovina A importância dessa prática é destacada pela sua contribuição para a maximização de características desejadas nos rebanhos, como qualidade de carne, eficiência reprodutiva e resistência a condições ambientais adversas. Este trabalho descreve e analisa as técnicas avançadas utilizadas nesse processo, incluindo seleção genômica, sexagem de embriões, produção in vitro, protocolos não cirúrgicos, sincronização reprodutiva, criopreservação de embriões e uso de (...) marcadores de fertilidade. A compreensão aprofundada dessas técnicas é fundamental para o sucesso da transferência de embriões, bem como para a capacidade de personalizar e aprimorar as características específicas dos rebanhos. Enfatizando a importância da expertise de profissionais especializados em reprodução bovina, este trabalho busca oferecer uma visão abrangente das práticas atuais e avanços tecnológicos nesse campo. Ao unir ciência e prática, torna-se importante a comparação de técnicas, bem como relacionar resultados eficientes para promover qualidade genética, trazer a sustentabilidade e envolver a técnica em um cenário atualizado da indústria. Palavras-chave: Embriões; Hormônio; Reprodutor. -/- Abstract Embryo transfer into cattle has the main objective of improving genetic improvement and optimizing bovine reproduction. The importance of this practice is highlighted by its contribution to maximizing desired characteristics in herds, such as meat quality, reproductive efficiency and resistance to environmental conditions adverse. This work describes and analyzes the advanced techniques used in this process, including genomic selection, embryo sexing, in vitro production, non-surgical protocols, reproductive synchronization, embryo cryopreservation and the use of fertility markers. An in-depth understanding of these techniques is critical to the success of embryo transfer, as well as the ability to customize and enhance specific herd characteristics. Emphasizing the importance of the expertise of professionals specialized in bovine reproduction, this work seeks to offer a comprehensive view of current practices and technological advances in this field. When combining science and practice, it becomes important to compare techniques, as well as relate efficient results to promote genetic quality, bring sustainability and involve the technique in an updated industry scenario. Keywords: Embryos; Hormone; Reproducer. -/- REFERÊNCIAS BIBLIOGRÁFICAS ABIEC. Associação Brasileira das Indústrias Exportadoras de Carnes. Beef Report. Perfil da Pecuária no Brasil. v.6, p. 7, 2021. ALVAREZ, R. Transfer of blastocysts derived short-term in culture of quality morulae in vivo. Domestic Animals. v.9, p. 790, 2007. ALVES, N. G. Atividade Ovariana em Fêmeas Bovinas da Raça Holandesa e Mestiças Holandês x Zebu, Durante Dois Ciclos Estrais Normais Consecutivos. Revista Zootecnia. v.7, p. 86, 2002. ANDRADE, J. Use of hormone treatments to superovulation Nelore donors. Reproduction Science. v.9, p. 70, 2002. Associação Brasileira de Inseminação Artificial (ASBIA). Index Asbia 2021. v.7, p. 6, 2021. Associação Brasileira de Inseminação Artificial (ASBIA). Index ASBIA Mercado, v.8, p. 6, 2019. BARROS, C. M. Tratamentos superestimulatórios utilizados em protocolos para a transferência de embriões bovinos. Acta Scientiae Veterinariae. v.9, p.8, 2007. BARUSELLI, P. S. Avaliação do mercado de IATF no Brasil. Boletim Eletrônico do Departamento de Reprodução Animal – FMVZ/USP, 1. ed., v.8, p.7, 2019. BARUSELLI, P. S.; CATUSSI, B. L. C.; ABREU, L. A.; ELLIFF, F. M.; SILVA, L. G.; BATISTA, E. S.; CREPALDI, G. A. Evolução e perspectivas da Inseminação Artificial em bovinos. Revista Brasileira de Reprodução Animal, v.43, n.2, p.308-314, 2019. 13 BARUSELLI, P. S. IATF gera ganhos que superam R$ 3,5 bilhões nas cadeias de produção de carne e de leite. Boletim Eletrônico do Departamento de Reprodução Animal/FMVZ/USP, 2.ed., v.8, n.8, p.7, 2019. BINELLI, M. Anti-luteolytic to improve in cattle. Acta Scientiae Veterinariae. v.9, p.8, 2001. BÓ, G. A. Manipulação hormonal do ciclo estral em doadoras e receptoras de embrião bovino. Acta Scientiae Veterinariae. v.9, p.7, 2004. BÓ, G.; MAPLETOFT, R. Evaluation and of bovine. Animal Reproduction. v.8, p.9, 2013. BUSS, V. Efeito da dose e momento da administração de eCG em protocolos de IATF aplicados e vacas de corte em anestro. Universidade Federal do Pampa, Dissertação – Programa de Pós-Graduação em Ciência Animal, v.8, n.8, p.9, 2020. Centro de Estudos Avançados em Economia Aplicada (CEPEA). Boletim do leite. São Paulo, Ano 25, n.286, 2019. CHAVES, D. F.; ALVES, M. J. Protocolo de receptoras de embriões: índices de aproveitamento de corpo lúteo e taxa de prenhez. Animal Reproduction. v.9, p.7, 2023. DA SILVA, Emanuel Isaque Cordeiro. Fisiologia Clínica do Ciclo Estral de Vacas Leiteiras: Desenvolvimento Folicular, Corpo Lúteo e Etapas do Estro. 2020. DA SILVA, Emanuel Isaque Cordeiro. Transferência de Embriões nos Animais e a Indústria de Embriões no Brasil. 2020. DALCIN, L.; LUCCI, C. M. Criopreservação de embriões de animais de produção: princípios criobiológicos e estado atual. Rev. Bras. Reprod. Anim. v.7, p.7, 2010. DANTAS, K. S. A. Seleção de receptoras em um programa de transferência de embriões (PIVE) em bovinos no nordeste do Brasil. Ciência Animal. v.9, p.7, 2018. D’AVILA, C. A.; MORAES, F. P.; LUCIA J. R. T.; GASPERIN, B. G. Hormônios utilizados na indução da ovulação em bovinos – Artigo de revisão. Revista Brasileira de Reprodução Animal, v.43, n.4, p.797-802, 2019. DEMÉTRIO, D. G. B. Colheita e transferência de embriões bovinos. Dissertação (Mestrado em Reprodução Animal) – Faculdade de Medicina Veterinária e Zootecnia da UNESP, Campus de Botucatu, São Paulo. v.9, p.76, 2003. FAO – Organização das Nações Unidas para a Alimentação e Agricultura. O Estado da Insegurança Alimentar e Nutrição no Mundo (SOFI) 2021. Faculdade de Medicina Veterinária e Zootecnia da UNESP. v.4, n.6, p.6, 2021. FILHO, L. C. C. Fatores que interferem na eficiência reprodutiva de receptoras de embrião bovino. Arq. Ciênc. Vet. Zool. v.7, p.9, 2013. GONZÁLEZ, F. H. D. Introdução a Endocrinologia Reprodutiva Veterinária. UFRGS. v.9, p.7, 2002. GOODHAND, K. In vivo recovery and vitro embryo from bovine aspirated at frequencies or FSH treatment. Animal Reproduction. v.8, p.87, 1999. 14 HAFEZ, E. S. E.; HAFEZ, B. Reprodução animal. 7ed. Barueri: Manole. v.7, p.7, 2004. HONORATO, M.T. Importância da escolha de receptoras em um programa de transferência de embriões em bovinos. Barueri: Manole. v.8, p.6, 2013. HOPPER, R. Bovine Reproduction. Blackwell. v.8, p.8, 2015. IBGE. Instituto Brasileiro de Geografia e Estatística. Pesquisa da Pecuária Municipal 2021 (PPM 2021). IBGE. v.9, n.7, p.7, 2021. KONIG, H. E.; LIEBICH, H. G. Anatomia dos animais domésticos: texto e atlas colorido. Vol.2. Porto Alegre: Artmed, v.2, p.4, 2004. MARTINS, F. S. Fatores reguladores da foliculogênese em mamíferos. Rev Bras Reprod Anim. v.3, p.9, 2008. MELLO, R. R. C. Desenvolvimento folicular inicial em bovinos. Rev. Bras. Reprod. Anim. v.8, p.9, 2013. OLIVEIRA, A. F. M. Principais hormônios que controlam o comportamento reprodutivo e social das fêmeas ruminantes – Revisão. Rev. Bras. Reprod. v.9, p.8, 2014. OLIVEIRA, C. S. Biotécnicas da Reprodução em Bovinos. EMBRAPA, v.8, p.8, 2014. PASA, C. Transferência de embriões em bovinos. Biodiversidade. v.9, p.9, 2008. PENITENTE FILHO, J. M. Produção de embriões bovinos in vivo e in vitro. Revista CFMV, Ano XX. v.8, p.8, 2014. PHILLIPS, P. E.; JAHNKE, M. M. Embryo Transfer (Techniques, Dono rs, and Recipients). Vet Clin Food Anim, v.9, p.8, 2016. RODRIGUES, J.; BERTOLINI, M. Biotecnologias da reprodução animal: de Aristóteles à edição gênica. Rev. Bras. Reprod. Anim. v.8, p.7, 2019. SANTOS, K. J. G. Biotecnologias reprodutivas e fisiologia reprodutiva da fêmea bovina – conhecimento para o sucesso. Rev. Bras. Reprod. Anim. v.8, p.98. 2012. SANTOS, P. H. Impactos da superestimulação ovariana sobre a diferenciação das células da granulosa bovina. Dissertação de Mestrado em Farmacologia e Biotecnologia – UNESP, v.8, p.8. 2017. SILVA, P. R. B. Regulação farmacológica do ciclo estral de bovinos. UNESP. v.9, p.8. 2011. (shrink)

Philosophers of science often suggest that the key feature of scientific research is striving for objectivity and that we should evaluate scientific practice by whether it is objective or not. In this paper, we will analyze several definitions of scientific objectivity to illustrate the complex meaning of this term and examine its role in evaluating scientific practice. First, we will introduce Lorraine Daston and Peter Galison's standpoint concerning the historical connection between the genesis and development of scientific objectivity and the (...) practices of visual representation in the research practice of the 19th and 20th centuries. We will accomplish that by outlining the process of establishing scientific objectivity as an epistemic virtue and a vital feature of the "scientific self ". Subsequently, using Heather Douglas and Mar-ianne Janack's conceptual analysis of scientific objectivity, we will show that scientific objectivity is characterized by an "irreducibility of meaning" and an "endemic instability" caused by the overuse of metaphors in defining this concept. In the final section, in light of contemporary problems such as the crisis of reproducibility, we examine to what extent philosophical definitions help test the objectivity of scientific practice and point to an intriguing attempt to define "objectivity for the research worker" using the model proposed by Noah van Dongen and Michał Sikorski. (shrink)

In this paper I focus on the topic of reproducibility (and irreproducibility) of aesthetic experience and effects, distinguishing it from the traditional subject of artifact reproducibility. The main aim is to outline a typology of the various kind of irreproducibility of aesthetic experience and to draw some implications for the aesthetic discussion concerning contemporary art. Depending on the type of artwork, we can define the difference (or the “ratio”) between aesthetic experience in the presence of the artwork and (...) aesthetic experience in its absence, that is, in the presence of its reproductions or documentations. For instance, in an easily reproducible painting the difference between experiencing the real artwork or its reproduction could be considered relatively small, while the difference between real experience and reproduction would be high in a complex roomfilling installation. This ratio could depend on ontological, material, or practical reasons and could also depend on the technological means of reproduction and documentation. In conclusion, following Groys (2017), I will suggest that the application of different "strategies of irreproducibility” testifies the urge to escape the replicability of aesthetic experience and the desire to generate forms of uniqueness and exclusivity in the fruition of art, and could therefore be seen as one of the reasons why art today is strongly based on documentations, installations or performative events. You really need to make the real effort to queue up and attend them, no substitute would be otherwise possible. (shrink)

Scientists who engage in science and the scientific endeavor should seek truth with conviction of morals and commitment to ethics. While the number of publications continues to increase, the number of retractions has increased at a faster rate. Journals publish fraudulent research papers despite claims of peer review and adherence to publishing ethics. Nevertheless, appropriate ethical peer review will remain a gatekeeper when selecting research manuscripts in scholarly publishing and approving research applications for grant funding. However, this peer review must (...) become more open, fair, transparent, equitable, and just with new recommendations and guidelines for reproducible and accountable reviews that support and promote fair citation and citational justice. We should engineer this new peer-review process with modern informatics technology and information science to provide and defend better safeguards for truth and integrity, to clarify and maintain the provenance of information and ideas, and to rebuild and restore trust in scholarly research institutions. Indeed, this new approach will be necessary in the current post-truth era to counter the ease and speed with which mis-information, dis-information, anti-information, caco-information, and mal-information spread through the internet, web, news, and social media. The most important question for application of new peer-review methods to these information wars should be ‘Who does what when?’ in support of reproducible and accountable reviews. Who refers to the authors, reviewers, editors, and publishers as participants in the review process. What refers to disclosure of the participants' identities, the material content of author manuscripts and reviewer commentaries, and other communications between authors and reviewers. When refers to tracking the sequential points in time for which disclosure of whose identity, which content, and which communication at which step of the peer-review process for which audience of readers and reviewers. We believe that quality peer review, and peer review of peer review, must be motivated and maintained by elevating their status and prestige to an art and a science. Both peer review itself and peer review analyses of peer reviews should be incentivised by publishing peer reviews as citable references separately from the research report reviewed while crossreferenced and crosslinked to the report reviewed. (shrink)

First, I offer a short overview on the classical occidental philosophy as propounded by the ancient Greeks and the natural philosophies of the last 2000 years until the dawn of the empiricist logic of science in the twentieth century, which wanted to delimitate classical metaphysics from empirical sciences. In contrast to metaphysical concepts which didn’t reflect on the language with which they tried to explain the whole realm of entities empiricist logic of science initiated the end of metaphysical theories by (...) reflecting on the preconditions for foundation and justification of sentences about objects of investigation, i.e. a coherent definition of language in general, which was not the aim of classical metaphysics. Unexpectedly empiricist logic of science in the linguistic turn failed in the physical and mathematical reductionism of language and its use in communication, as will be discussed below in further detail. Nevertheless, such reflection on language and communication also introduced this vocabulary into biology. Manfred Eigen and bioinformatics, later on biolinguistics, used ‘language’ applied linguistic turn thinking to biology coherent to the logic of science and its formalisable aims. This changed significantly with the birth of biosemiotics and biohermeneutics. At the end of this introduction it will be outlined why and how all these approaches reproduced the deficiencies of the logic of science and why the biocommunicative approach avoids their abstractive fallacies. (shrink)

Will I die? As a hypothesis, in my natural scientific understanding, the psyche, is nothing more than, and exclusively just some states of my living brain – I will die as a result of his death. -/- In presented answer, psyche – itself own immediate reality itself, that is – undoubted. -/- This work was performed in reality “in the first person” (“subjective reality”, “phenomenal consciousness”). To realize, how, what it is the reality of the “in the first person” let’s (...) imagine ourselves as an experimenter, who does not replace reality with reasoning about it. – Now for us, as experimenters, how (what it is) psychic is an immediate and undoubted reality. And the awareness of “I am” is a direct reality, and not knowledge about it, which is always doubtful. That is, in psychic reality, nothing prevents us from answering undoubtedly and definitively the question, asked by this psychic reality itself about itself. The author acts from the position of “being in reality – not going beyond its limits, for example, into philosophy” (philosophy, including methodology, is the replacement of reality itself with always dubious reasoning about reality) – explores phenomenal consciousness (“psychic”) directly and as an immediate reality. That is, this work is the mastery of psychic reality through subjective-psychical experimentation – don’t philosophize, but experiment! -/- For example, Descartes, introspectively experimenting in his own psyche reality with his own psyche, informed us about the immutability of the “mind” and proposed to understand this immutability as our own immortality: “the mind does not represent any combination of accidents, it is a pure substance, and although all its accidents are subject to change, it understands some things, it desires others or feels others, etc. – nevertheless, in itself it does not change; and as for the human body, it changes, if only because they are subject to a change in the shape of some of its parts. It follows from this that the body perishes very easily, while the mind, by its very nature, is immortal” (Декарт Р., p. 13). Note that, Descartes did not realize that he was immortal, but logically deduced his own immortality from the immutability of the mind. However, Descartes’ unchanging “mind” itself is such that there is something to die. And in my natural scientific understanding, the immutability of the mind does not imply its immortality – it will die without changing in its subjective self-perception, while instantly fading away as a result of brain death. Psyche (psychical) – a designation of the fact that this is one’s own immediate reality (that is, undoubtedly) – how (what) I myself am immediately, undoubtedly, and that immediate reality of mine, how and through which I myself and everything in general for me there is, and which is exclusively the only one for me. It should be noted that while I am unconscious (brain injury or dreamless sleep), there is nothing at all. -/- But this does not mean that “I”, having completely gone into oblivion, I'll die. This does not exclude that, I will disappear completely into oblivion and does not exist, but (at the same time) “I” – am. So, let’s define immortality as the impossibility of dying because there is nothing to die (psychic, but is such that there is nothing to die – is immortal) and will make a conclusion important for this work: if I am, as psyche, exclusively only is such that there is something to die and nothing else, then, therefore, my death is not excluded. But am I like that? The idea of this work is that I, as a psyche can to manifest (reveal) and realize myself as such (I such), that there is nothing to die, but (at the same time) I – am. I will realize of myself as immortal – such that to die (to decease) nothing. In other words, if I will approach with a bias and, acting purposefully, will reveal the subjective reality “I (psyche) such is that to die (to decease) nothing, but I – am”, that is – I am immortal, that the hypothesis “I will die” will falsified and excluded. -/- To realize this in the work, it is proposed to use the subject-object model, shift the boundary of “I” to the pole of the subject and become objectless, manifesting (revealing) oneself as such that there is nothing to die. Therefore, the aim (goal) of the work – to realize: I – am, but such that there is to die (decease) nothing. To become objectless and wondering about the possibility to dying, as a result, or I will exclude the immortality of the manifested state, or I will manifest (will reveal) immortal undoubtedly and definitively. -/- At the same time, I, as a subject, am “a necessary pole of subject-object relations. … An object is what the activity of … a subject is directed at. … In fact, everything that exists can become an object. … it is important to keep in mind the fundamental fact that the object is always outside the subject, does not merge with it. This externality also takes place when the subject deals with the states of his own consciousness, his Self ... it is important to emphasize that the relation of the subject and the object is not the relation of two different worlds, but only two poles as part of some unity” (Лекторский В.А., p. 6-7). That is, everything that I find existing in myself, this (such) is as an object. “The subject always refers to all “objects”, but it can never become an object for itself” (Титлин Л.И., p. 23). “… you will not be able to see the seeing vision ...” (Титлин Л.И., p. 40), and in this model this implies the “limit” of the subject. As the limit of the subject, I am “objectless”. And, therefore, in its own pole the subject is “ideal” – in its (own) limit (as its own limit, its own limit), I do not exist for myself (non-existent). -/- Using the “fact of the mobility of the boundaries of the subject” (for example, Тхостов А.Ш., p. 16), I have the opportunity to “pull” the boundary of the “I” into myself and become my own limit. At the same time, it is necessary to realize and accept that “inside” the limit of the subject and behind – “beyond of the subject”, and in general the very “inside” and “behind” in this version – unreality. In such a subject limit, the required paradoxical subjective state is assumed – I exist and see, but at the same time I am such that I do not exist for myself, that is, I am, but (subjectively such that) there is nothing to die (“immortality”). -/- Accordingly, the following tasks are indicated in the experiment: 1. In the object-subject sphere of visual perception, shift (and shift) the boundary of “I” into oneself –» to run into one’s own limit and become one’s own limit (without thickness: without depth, without “from within” and without reverse side) –» 2. Having become your own limit, which in its own limit is, but for myself I do not exist (non-existent), realize: • Myself – I am and this is real; • Will I die? – or there is nothing to die, which of the options is to me, as a psyche (as itself the psychic “I”), is applicable: • or I am such that it is not impossible that I will die, and the realized state is not immortal; • or “I” am such that “I” – am (is reality), but such that myself “I” to die nothing, that is, my own immortality – I am immortal; • Is this real? -/- Instruction for reproducing the target result: sequence of actions and results in a subjective-psychic experiment (hereinafter referred to as SPE) -/- At a distance of 25-40 cm from the wall (so that the wall occupies the entire field of view or its overwhelming part), • Here and now, focus on your face: “I am” – reality (and not is the knowing about it). • In yourself step back and look out of yourself at this wall. • Without moving your head, cover the field of vision with your attention as wide as possible and at the same time perceive everything at once (all this) as a single whole. • Perceive a high and wide wall (option: look up at an angle of 135-150 degrees in front of you) in such a way that the space (volume) surveyed by you without turning your head is a closed asymmetrical “lens” • limited in a circle in the periphery of the field of view, • convex in you; You – the beholder, rearwards concave in self (“subject”) – which one of you are watching? • Without moving your head, perceive the field of view as a single whole –» • Into yourself “draw in” –» “backing away” –» step back from everything –» • lean back into yourself –» up to dead-end limit –» • become a dead end itself – a concave (reflector-like) limit-plane. • You – into yourself – backward concave – a perceiving visual screen (limit-dead end), plane –» • lean back and press –» • something in general somehow inside the dead-end plane and behind the dead-end plane, as well as “inside” and “behind”, “behind the dead-end plane” – unreality; • myself – a dead-end plane without thickness (depth), without “inside”, without a reverse side for oneself. • –» That is, as a psychic reality (what is it psychically) will I die? –» or • Something there is, and that is I will die (it is possible); or • I am such that there is nothing to die, but I – am. or • Subjective-psychic experiment is incomplete… • –» Realize that this is reality (realize the reality of it) and emphasize (answer). -/- As a result, “I” am, but there is nothing to die/not to die, that is, the hypothesis “I will die” is unrealistic. -/- Remarks -/- • Each completed SPE is completed with the target result: “I am such that there is nothing to die, but I – am”. And the that what I will die (not excluded) does not correspond to this, that is unreality and is excluded by this. • But I am not such that I will not die. The concepts “I will die/ I will not die” to me, as a psyche are not applicable. That is, I, as a psyche, is immortal, but I am not eternal (not eternal – endlessly lasting, such that there is something to last) – to last, to be eternal and to end there is nothing. This is “immortality”. • In the target result of this work, I – am, but such that there is nothing to die/not die (“immortality”). And such a “I” is not the Atman of the Hindu schools of Nyaya, Vaisheshika and Purva Mimamsa, which E.A. Torchinov. Since the “I” – psychic, and not a substance with the psyche as an attributes. • According to illusionism, what I am as a result of the experiment given in the work is an illusion. And the impression of immortality is a product of the brain. But in reality I am such that I will die (it is not excluded). However, it is necessary to realize that illusionism is a detached reasoning about the “I”, but not is the self itself. And to what I am (as psiche), reasoning and questions about the reality of the “I” (for example, question: am I really like this, what am I like as psyche?) and other expressing illusionism do not correspond. That is, subjectively (psychic, in the psychic reality of the “first person”, in first person perspective), the illusionism of the “I” is unreality. Subjectively (psychic, in the psychic reality of the “first person”, in first person perspective), this is undeniable and final. • Reasoning about what such a “I” is in this (mine) or not in this brain, as well as (for example, holding a real skull in my hands), questions like “how (or, but now where is it here) such “I” – how is it after brain death?” – To the fact that is such an “I” these questions do not correspond and is falsified by this. • After being unconscious, the impression remains that I'm is not and that there is nothing at all. That is, my “unconsciousness” is psychic indistinguishable from my non-existence. However, science has not shown, but and it is not excluded that before and after I exist physically (there is something to die), I still or I no longer exist, there is still or nothing to die as a soul, substance, or otherwise. But what I am in the target result of this work is what I – am, and not “died and already now or still unreality” and I am such that there is nothing to die, this is – reality. That is, I will die? – there is nothing (to die), but I – am (reality), even if I am not (don’t exist). Or I do not exist as something. • I am such that there is nothing to be and die, but I am. And subjectively (psychic, in the psychic reality of the “first person”, in first person perspective), this immortality is – reality. But this reality eludes my rational explanation. -/- Conclusion -/- Will I die? – In the target result the I am, but at the same time I am such that there is nothing to die. That is, I am immortal, but at the same time, I am not eternal (“I” not something eternal (endlessly continuing)) – I am such that to be eternal there is nothing. And, if we accept the subjective (psychic, “first person”, in first person perspective) reality without trying to understand it rationally, then I am exactly like that – I realize that this is my undoubted nature. That is, “I will die / I will not die” is an unreality. Subjectively (psychic, in the psychic reality of the “first person”, in first person perspective), it is undoubted and final. Despite the unscientific nature, this work is a way of mastering reality. The author would be grateful for the identified and shown unreality of the fact that the “I” – am, but such that there is nothing to die, and ideally, the awareness: “I will die (not excluded).” -/- Bibliography -/- Декарт Р., Размышления о первой философии //Декарт Р. Соч.: В 2 т. Т. 2. М., 1994. Лекторский В.А. Субъект в истории философии: проблемы и достижения // Методология и история психологии. 2010. Том 5. Выпуск 1. С. 5-18. Титлин Л.И. Проблема субъекта в индийской философии («Пудгалавинишчая» Васубандху) [Текст] / [Л. И. Титлин]; Федеральное государственное бюджетное учреждение науки Институт философии Российской академии наук. – Москва: ОнтоПринт: Сделано-Сказано, 2018. – 361, [1] с. Тхостов A. Ш. Культурно-историческая патопсихология: монография, – М.: Канон+ РООИ «Реабилитация», 2020. – 320 с. Торчинов Е.А. «Словарик индуизма» (Дата написания: 2003; дата файла: 15.06.2007). Торчинов Е.А. Пути философии Востока и Запада: познание запредельного — СПб.: «Азбука-классика», «Петербургское Востоковедение», 2005. — 480 с. ISBN 5-352-01371-5 (Азбука-классика) ISBN 5-85803-258-3 (Петербургское Востоковедение). -/- Скончаюсь? – я бессмертен (как осознать бессмертие «от первого лица») -/- Скончаюсь? В качестве гипотезы в моем естественно-научном понимании психическое (каково психически), это не более чем, и исключительно только всего лишь некоторые состояния моего живого мозга – скончаюсь в результате его смерти. -/- В представленном ответе психическое – сама собственная непосредственная реальность, то есть, то, каково психически, это – несомненно. -/- Данная работа выполнена в реальности «первого лица» («субъективная реальность», «феноменальное сознание»). Чтобы осознать то, как, каково это, представим себя экспериментатором, который не подменяет реальность рассуждениями о ней. – Теперь для нас, как экспериментаторов, то, как (каково) психически, это непосредственная и несомненная реальность. И осознание «я есть», это непосредственная реальность, а не знание об этом, которое всегда сомнительно. То есть, в психической реальности, на вопрос, заданный самой этой психической реальностью самой себе о себе самой, нам ничто не запрещает ответить несомненно и окончательно. Автор действует с позиции «быть в реальности – не выходить за ее пределы, например, в философию» (философия, включая методологию, это подмена самой реальности всегда сомнительными рассуждениями о реальности) – исследует феноменальное сознание («психическое») непосредственно и в качестве непосредственной реальности. То есть, данная работа, это овладение психической реальностью посредством субъективно-психического экспериментирования – не философствуй, а экспериментируй! -/- Например Декарт, интроспективно экспериментируя в собственной психической реальности с собственным психическим, сообщил нам о неизменности «ума» и предложил эту неизменность понять в качестве нашего собственного бессмертия: «ум не представляет какого-то соединения акциденций, являет собой чистую субстанцию и, хотя все его акциденции подвержены изменению — он то понимает какие-то вещи, то желает другие или чувствует третьи и т.д.,— тем не менее сам по себе он не изменяется; а что касается тела человека, то оно изменяется хотя бы уже потому, что подвержены изменению формы некоторых его частей. Из этого следует, что тело весьма легко погибает, ум же по самой природе своей бессмертен» /Декарт Р., стр. 13. Заметим, Декарт не осознавал себя бессмертным, а логически вывел собственное бессмертие из неизменности ума. Однако, неизменный «ум» Декарта таков, что скончаться есть чему. А в моем естественно-научном понимании из неизменности ума не следует его бессмертие – он, не изменяясь в своем субъективном само-восприятии, при этом мгновенно угаснув в результате смерти мозга, скончается. Психически (психическое) – обозначение того, что это сама собственная непосредственная реальность (то есть – несомненно) – то, как (каково) я сам непосредственно, несомненно, и та моя непосредственная реальность, как и посредством чего я сам и всё вообще для меня есть, и которое для меня исключительно единственное. Следует заметить, что пока бываю без сознания (травма мозга или сон без сновидений), ничего и никак нет вообще. -/- Но это не значит, что «я» ушедши в небытие окончательно – скончаюсь. Этим не исключено, что таковой ушедший в небытие «я» не существую, но (при этом) есть. Итак, определим бессмертие, как невозможность скончаться потому, что скончаться нечему (например, если «умерший» психически есть, но уже таков, что скончаться больше нечему, то теперь он бессмертен) и сделаем важный для данной работы вывод: если психически я исключительно только таков, что скончаться есть чему и ни каков иначе, то, следовательно, то, что скончаюсь, это не исключено. Но таков ли я? Идея данной работы в том, что мне удастся проявить (выявить) и осознать себя таковым (я таков), что скончаться нечему, но (при этом) я есть. Иначе выражаясь, если я подойду предвзято и действуя целеустремленно, выявлю субъективную реальность «я есть, но таков, что скончаться нечему» – то смерть мне, как психическому несвойственна, то есть, я бессмертен – гипотеза возможности субъективно скончаться («я скончаюсь») будет фальсифицирована и исключена. -/- Чтобы это реализовать в работе предлагается воспользоваться субъект-объектной моделью, сдвинуть границу «я» в полюс субъекта и стать безобъектным, проявившись (выявившись) собой таковым, что скончаться нечему. Следовательно, цель работы – осознать: я таков, что есть, но скончаться нечему. Стать безобъектным и задаваясь вопросом о возможности скончаться, или исключу бессмертие проявленного состояния, или проявлюсь (выявлюсь) бессмертным несомненно и окончательно. -/- При этом, я, как субъект, являюсь «необходимым полюсом субъектно-объектных отношений. … Объект – то, на что направлена активность … субъекта. … В действительности объектом может стать все, что существует. … важно иметь в виду тот принципиальный факт, что объект всегда внеположен субъекту, не сливается с ним. Эта внеположность имеет место и тогда, когда субъект имеет дело с состояниями собственного сознания, своим Я … важно подчеркнуть, что отношение субъекта и объекта – это не отношение двух разных миров, а лишь двух полюсов в составе некоторого единства» /Лекторский В.А., стр. 6-7. То есть, всё, что нахожу в себе существующим, это (таковое) есть в качестве объекта. «Субъект – всегда относится ко всем «объектам», но он никогда не может стать объектом для самого себя» /Титлин Л.И., стр. 23. Иначе это выражая – «ты не сможешь увидеть видящего видение…» /Титлин Л.И., стр. 40, и в данной модели таковое предполагает «предел» субъекта. Как предел субъекта я «безобъектен». То есть, «идеален» – своим (собственным) пределом (в качестве собственного предела) самим для себя не существую (несуществующий). -/- Используя «факт подвижности границ субъекта» /например, Тхостов А.Ш., стр. 16, я имею возможность границу «я» в себя-назад «втянуть» и стать собственным пределом. При этом необходимо осознать и принять, что внутри предела субъекта и сзади – «за пределом субъекта», и вообще само «внутри» и «сзади» в этой модели – нереальность. Таким субъектным пределом предполагается требуемое парадоксальное субъективное состояние – я есть и вижу, но при этом я таков, что для себя не существую, то есть, я есть, но (психически таков, что) умереть нечему («бессмертие»). -/- Соответственно, в эксперименте обозначаются следующие задачи: 1. В объект-субъектной сфере зрительного восприятия сдвинуть (и сдвинув) границу «я» в себя-назад –» упереться в собственный предел и стать самим собственным пределом (без толщены: без глубины, без «внутри» и без обратной стороны) –» 2. Став собственным пределом, которым есть, но для себя не существую (несуществующий), осознать: • Себя – я есть и это реально; • Скончаюсь? – есть ли чему скончаться или скончаться нечему, какой из вариантов мне (как психическому «я») свойственен: • или я таков, что то, что скончаюсь не исключено, и реализованное состояние не бессмертно; • или я есть, но таков, что скончаться нечему, то есть, собственное бессмертие – я бессмертен; • Реальность ли это. -/- Инструкция воспроизведения целевого результата: последовательность действий и результатов в субъективно-психическом эксперименте (далее СПЭ) -/- На расстоянии 25-40 см от стены (так, чтобы стена занимала всё поле зрения или его подавляющую часть), • Здесь и сейчас сосредоточьтесь на своём лице: «я есть» – реальность (а не знание об этом). • В себе отстранитесь назад и смотрите из себя на эту стену. • Не двигая головой, охватите поле зрения вниманием предельно широко и одновременно всё сразу (всё это) воспримите единым целым. • Высокую и широкую стену (вариант: смотрите вверх под углом 135-150 градусов перед собой) воспримите так, что обозреваемое вами без поворота головы пространство (объем), это – ограниченная по окружности в периферии поля зрения замкнутая несимметричная «линза» • плоская с противоположной вам стороны • и выпуклая в вас; Вы – вогнутый в себя-назад смотрящий («субъект») – каков? – кто из вас сейчас на всё это смотрит? • Не двигая головой, поле зрения воспримите единым целым –» • В себя-назад «втянитесь» –» и «пятьтесь» –» «за мысли» и за всё вообще –» из этого всего назад вытесняясь –» от всего вообще взад отстранитесь –» • собой в себя-назад подайтесь и упершись в собственный (себя) задний к объектному обращённый (развернутый) тупиковый предел –» • станьте самим пределом-тупиком – в себя-назад вогнутой (рефлектор-подобной) пределом-плоскостью смотрящей – воспринимающим зрительным экраном –» станьте плоскостью-тупиком –» • «проскользните» по себе – плоскости-тупику и охватите вниманием целиком –» • собой – самим плоскостью-тупиком назад надавить, нажать –» • осознать: что-то как-то внутри плоскости-тупика и сзади за плоскостью-тупиком, и там вообще «что-то как-то», а также само «внутри» и «сзади», «за плоскостью-тупиком» и вообще «там» – нереальность; • самого себя – плоскости-тупика без толщины (глубины), без «внутри», без обратной стороны для себя нет. • –» То есть – в качестве психической реальности (каково психически) я скончаюсь? –» или • скончаться есть чему – скончаюсь (не исключено). или • я таков, что скончаться нечему, но я есть. или • субъективно-психический эксперимент не завершён. • –» Осознайте, что это – реальность (осознать реальность этого) и подчеркните (ответ). -/- В результате я есть, но скончаться/не скончаться нечему, то есть гипотеза «скончаюсь» – нереальность. -/- Замечания -/- • Каждый завершённый СПЭ завершён целевым результатом: «я таков, что скончаться нечему, но я есть». И тому, каков я в результате СПЭ, то, что скончаться есть чему – скончаюсь (не исключено) не соответствует, то есть нереальность и этим исключено. • То есть, я и не таков, что не скончаюсь. «Я скончаюсь/не скончаюсь» ко мне, как к психике, неприменимо. Иначе это выражая, тому, каков я, смерть несвойственна. То есть, я, как психика (психическое), бессмертен, но я не вечен (не вечный – бесконечно длящийся, таковой, что есть чему длиться) – длиться, быть вечным и не скончаться нечему. Таково «бессмертие». • В целевом результате данной работы я есть, но таков, что скончаться/не скончаться нечему («бессмертие»). И таковой «я» не Атман индуистских школ ньяя, вайшешика и пурва-миманса, о котором сообщает Е.А. Торчинов. Так как «я» психичен, а не субстанция с психическим в качестве атрибута. • Согласно иллюзионизму, то, каков я в результате данного в работе эксперимента, это иллюзия. И впечатление бессмертия, это порождение мозга. А реально я таков, что скончаюсь (не исключено). Однако, необходимо осознать, что иллюзионизм, это отстраненные рассуждения о «я», но не сам я непосредственно. И тому, каков я психически (каково психически), рассуждения и вопросы о реальности «я» (например, таков ли я реально, каков психически?) и другие выражающие иллюзионизм «я» не соответствуют. То есть, каково психически, иллюзионизм «я» – нереальность. Психически, это несомненно и окончательно. • Рассуждения о том, что таковой «я» в этом (моем) или не в этом мозге, а также (например, держа в руках реальный череп), вопросы, типа «а как же (или, но теперь где же здесь) таковой «я» – как это после смерти мозга?» тому, каков таковой «я» эти вопросы не соответствуют. • После пребывания без сознания остается впечатление, что без сознания меня нет и ничего никак нет вообще. То есть, моё «бессознание» психически неотличимо от моего несуществования (небытия). Однако, наукой не показано и не исключено то, что до и после того, как я есть физически (скончаться есть чему), меня ещё или уже нет, скончаться ещё или уже нечему в качестве души, субстанции или как-то иначе. Но, то, каков я в целевом результате данной работы, таковой я есть, а не «скончался и уже теперь или ещё нереальность» и я таков, что скончаться нечему – реален (реалия). То есть, скончаюсь? – нечему (скончаться), но я есть, даже если меня нет (не существую). • Я таков, что быть и скончаться нечему, но я есть. И то, как (каково) психически, это бессмертие – реальность. Но эта реальность ускользает от моего рационального её объяснения. -/- Заключение -/- Скончаюсь? – в целевом результате я есть и вижу, но при этом я таков, что умереть (скончаться) нечему. То есть, я бессмертен, но при этом я не вечен (не нечто вечное (бесконечно длящееся)) – быть вечным нечему. И, если принять психическое реальностью не пытаясь понять это рационально, то я именно таков – осознаю, что такова моя несомненная для меня природа. То есть, «скончаюсь/не скончаюсь» – нереальность. Психически, это несомненно и окончательно. Несмотря на ненаучность, данная работа – способ овладения реальностью. Автор был бы признателен за выявленную и показанную нереальность целевого результата данной работы, а в идеале, за осознание: «скончаюсь (не исключено)». -/- Annex 2. The key essence of this work (only in Russian to convey the nuances without distortion) -/- Performed, expressed and transmitted initially by means of Russian, the native language of the author, and, in order to avoid distortions in the correspondence of the linguistic nuances of the reproduced subjective reality, it assumes an independent translation into the language of the experimenter by the experimenter himself in the process of reproducing the target result of this work. -/- «Я» скончаюсь? – нечему (скончаться), но «Я» есть. Will “I” die (decease)? – to die (decease) nothing, but “I” am. -/- Заметить: • Выполнено, выражено и передано изначально посредством русского – родного для автора языка и, чтобы избежать искажений соответствия языковых нюансов воспроизводимой психической реальности, предполагается самостоятельный перевод на язык экспериментатора самим экспериментатором в процессе воспроизведения целевого результата данной работы. • В «кавычки» взяты слова и выражения, требующие «субъективного» приведения в соответствие психическому содержанию. Подготовка: • Вам потребуется уединённое место (там, где вас не отвлекут). • На первоначальном этапе понадобится некоторое (возможно длительное) время для того, чтобы усвоить предложенный алгоритм действий в психической реальности в процессе реализации и воспроизвести целевой результат впервые. • Возможно, результату поспособствует отклонение от предложенного алгоритма «психических действий», импровизация в направлении целевого результата. • В процессе эксперимента количество попыток не ограничено и затраченное на это время не имеет значения. Необходим исключительно только именно целевой результат. Реализация: • В уединении встать перед плоской широкой и высокой (достаточно большой, чтобы её границы были на периферии вашего поля зрения) стеной, например, покрытой однородной светлой (но не белой) керамической, не глянцевой (не отражающей на вас свет или отвлекающих внимание изображений, не дающей бликов) плиткой с лёгким текстурным рисунком (позволяющим глазам «зацепиться» за стену и отчётливо воспринимать перед собой поверхность, а не «утонуть» в однородном (монотонном) пространстве), на расстоянии 25-40 см от неё (так, чтобы стена занимала всё поле зрения или его подавляющую часть) –» • Скончаюсь (1)? – каково психически (психическое), в моем естественно-научном понимании – это (я) не более чем и исключительно только некоторые состояния функционирующего (живого) мозга – скончаюсь, как и уже скончался каждый умерший мозг – того каждого, кто скончался, как реальности (реального, реалии) (2) уже теперь нет окончательно. Теоретически, если психически я исключительно только таков, что скончаться есть чему и ни каков иначе, то, следовательно, что (я) скончаюсь, это не исключено. • Глядя на стену, здесь и сейчас сосредоточиться на своём лице (и осознать): «я есть» – реальность (а не знание об этом) –» • В себе «отстраниться» назад – смотрю из себя на эту стену –» • Не двигая головой, охватить поле зрения вниманием предельно широко (поднять (вздернуть) брови, если это расширит поле зрения) и одновременно всё сразу (всё это) воспринять единым целым –» • Высокую и широкую стену (вариант: смотреть вверх под углом 135-150 градусов перед собой) воспринять так, что обозреваемое без поворота головы пространство (объем), это – ограниченная по окружности в периферии поля зрения замкнутая несимметричная «линза» • плоская (ограниченная стеной) с противоположной мне стороны • и «выпуклая в меня» –» • Я – «вогнутый» в «себя-назад» смотрящий, каков? – кто из меня сейчас на всё это смотрит? –» • Не двигая головой, поле зрения воспринять единым целым –» • в себя-назад «втянуться» –» и «пятиться» –» «за мысли» и за всё вообще –» из этого всего назад «вытесняясь» –» от всего вообще «взад отстраниться» –» • «собой» в себя-назад «податься» и «упершись» в «собственный (себя) задний к объектному обращённый (развернутый)» «предел тупиковый» («тупо-уперто») –» • «стать» самим «пределом-тупиком» – «в себя-назад вогнутой (рефлектор-подобной)» «пределом-плоскостью» смотрящей – воспринимающим «зрительным экраном» –» стать «плоскостью-тупиком» –» • «проскользнуть» по себе – плоскости-тупику и охватить вниманием целиком –» • собой — самим плоскостью-тупиком «назад надавить, нажать»: • осознать: «что-то как-то внутри плоскости-тупика» и «сзади – за плоскостью-тупиком», и «там вообще» «что-то как-то», а также само «внутри» и «сзади», «за плоскостью-тупиком» и вообще «там» – нереальность; • самого себя – плоскости-тупика без толщины (глубины), без «внутри», без обратной стороны для себя нет –» Собой – плоскостью-тупиком: • без глубины (толщины), без «внутри», без обратной стороны таков, что скончаться есть чему – скончаюсь (не исключено) –» • смотрю –» смотря –» «Непосредственно-психически» -/- Заметить: • Специфику используемых в данной работе слов (терминов), названий и выражений необходимо осознать в соответствии с (4.1.) (данный пункт смотрите ниже). • Необходимо от себя – (как) «смотрящего плоскости-тупика», такового, что скончаться есть чему, оттождествиться собой — «самим психическим» (каково психически) (3) –» • –» «отличить (4)» «Я» –» «Я-лик». • Отличив, и себя такового обозначая, но не имея в языке отличающего местоимения, именую «Я» (5). • «Соединённое-через-дефис-в-кавычках» реализовать и/или воспринять «одним-единым-целостным»; • Последовательность слов и знаков предполагает последовательность психических действий (алгоритм действий в собственном психическом); • Вопросительность слова, фразы или отдельной её, именно вопросительной части задаётся знаком «?» расположенным перед и после них. Требование к действию задаётся знаком «!» расположенным перед и после слова (фразы); • Субъективно-психический эксперимент завершён, если воспроизведен (4.1.), иначе субъективно-психический эксперимент не завершён. -/- Собой – плоскостью-тупиком … смотрю –» смотря –» -/- «Психически» (6) 1. ?кто? видит –» !отличить «Я»! –» 2. –» !«Я-видящий-лик»! –» 3. –» !«Я-лик»! –» 4. –» !«Я-ликом» всем «психически-назад-надавить(нажать)»: «Я» ?скончаюсь?! –» !«Я-ликом» всем «психически-назад-давить(жать)»: (4.1.) – нечему (7), но «Я» есть.! -/- Признательность: Согласно иллюзионизму, то, каков «Я» (как (каково) «скончаться нечему, но «Я» есть.»), реально, это не так (не таково). То есть, таковой «Я» нереален (нереальность), а реально – таков, что скончаюсь (не исключено). Однако, необходимо осознать, что это «отстраненные» от «Я» рассуждения о «Я», но не сам «Я» непосредственно. И тому, каков «Я» (как (каково) скончаться нечему, но «Я» есть.) таковое (рассуждения) не соответствует. То есть, эти рассуждения о «Я» – заблуждение. Это (как осознание) несомненно и окончательно. Не так? – за выявленную и показанную нереальность (того, что) «Скончаюсь? – нечему (скончаться), но «Я» есть.», за показанную реальность того, что скончаться не исключено, а в идеале, за осознание: «скончаюсь (не исключено)» я был бы признателен. -/- (Сноски) (1) Именно «скончаюсь, скончался», то есть – как реальности (реального, реалии) нет окончательно. (2) Реалия, реально, реален, реальность, реальное – само то, что (каково это) непосредственно, как само таковое – само то, каково познаваемое и как-либо моделируемое вне его познания и иного (вообще) моделирования. То есть, само само-осознание себя реальностью, например, «я-реалия», «я есть» или «скончаться – нечему, но «Я» есть.» – реальность. То есть – нам ничто не запрещает ответить на вопрос «скончаюсь?» несомненно и окончательно. (3) Психически (психическое) – то, как (каково) я сам непосредственно, несомненно, и та моя непосредственная реальность, как и посредством чего я сам и всё вообще для меня есть, и которое для меня исключительно единственное. Следует заметить, что пока бываю без сознания (травма мозга или сон без сновидений), ничего и никак нет вообще. Также само обозначение того, что это сама собственная непосредственная реальность (то есть – несомненно). И чтобы её осознать, представьте себя экспериментатором, который не подменяет реальность рассуждениями о ней. – Теперь для вас, как экспериментатора, то, как (каково) психически, это – несомненно (непосредственная несомненная реальность). Не философствуй (не рассуждай, не моделируй её), а экспериментируй! (4) «Я-Лик» – специфическое выражение, соответствующее психическому в данный момент СПЭ. (5) «Я» – целевой (конечный, «предельный») и «ключевой» результат данной работы. «Я» в данной работе не склоняется, выделено полужирным подчеркнутым шрифтом и заключено в кавычки. (6) «Каково психически» – то, как (каково) «Я» сам непосредственно, несомненно – само «первое лицо» (субъект психического), а также обозначение принятия позиции «первого лица» и сообщения «от первого лица». (7) Пока я бываю без сознания («бессознание», например, сплю без сновидений), моего сознания нет (оно сведено на нет, угасло) – ничего и никак нет вообще (это моё абсолютное небытие) – (каково) психически, мне скончаться нечем. А в целевом результате данной работы, психически (то есть – непосредственно), «Я» таков, что скончаться не нечем, а именно нечему, но при этом «Я» есть. (shrink)

This short piece reproduces Prof Nancy K. Napier’s book review posted on Amazon. The references are added for clarity.

The idea of artificial intelligence for social good is gaining traction within information societies in general and the AI community in particular. It has the potential to tackle social problems through the development of AI-based solutions. Yet, to date, there is only limited understanding of what makes AI socially good in theory, what counts as AI4SG in practice, and how to reproduce its initial successes in terms of policies. This article addresses this gap by identifying seven ethical factors that are (...) essential for future AI4SG initiatives. The analysis is supported by 27 case examples of AI4SG projects. Some of these factors are almost entirely novel to AI, while the significance of other factors is heightened by the use of AI. From each of these factors, corresponding best practices are formulated which, subject to context and balance, may serve as preliminary guidelines to ensure that well-designed AI is more likely to serve the social good. (shrink)

2015 Reprint of 1956 Printing. Full facsimile of the original edition. Not reproduced with Optical Recognition Software. Cybernetics is here defined as "the science of control and communication, in the animal and the machine"-in a word, as the art of steersmanship; and this book will interest all who are interested in cybernetics, communication theory and methods for regulation and control. W. Ross Ashby (1903-1972) was an English psychiatrist and a pioneer in cybernetics, the study of complex systems. His two books, (...) "Design for a Brain" and "An Introduction to Cybernetics," were landmark works. They introduced exact and logical thinking into the nascent discipline and were highly influential. Contents include: What is new -- Change -- The Determinate Machine -- The Machine with Input -- Stability -- The Black Box -- Quantity of Variety -- Transmission of Variety -- Incessant Transmission -- Regulation in Biological Systems -- Requisite Variety -- The Error-controlled Regulator -- Regulating the Very Large System -- Amplifying Regulation. (shrink)

This paper analyses the communicative and epistemic value of retweeting (and more generally of reposting content on social media). Against a naïve view, it argues that retweets are not acts of endorsement, motivating this diagnosis with linguistic data. Retweeting is instead modelled as a peculiar form of quotation, in which the reported content is indicated rather than reproduced. A relevance-theoretic account of the communicative import of retweeting is then developed, to spell out the complex mechanisms by which retweets achieve their (...) communicative goals. The last section outlines the epistemic threats posed by the increasing prevalence of retweeting on social media, linking them to the low reputational, cognitive and practical costs linked to this emerging form of communication. (shrink)

Philosophy and Memory Traces defends two theories of autobiographical memory. One is a bewildering historical view of memories as dynamic patterns in fleeting animal spirits, nervous fluids which rummaged through the pores of brain and body. The other is new connectionism, in which memories are 'stored' only superpositionally, and reconstructed rather than reproduced. Both models, argues John Sutton, depart from static archival metaphors by employing distributed representation, which brings interference and confusion between memory traces. Both raise urgent issues about control (...) of the personal past, and about relations between self and body. Sutton demonstrates the role of bizarre body fluids in moral physiology, as philosophers from Descartes and Locke to Coleridge struggled to control their own innards and impose cognitive discipline on 'the phantasmal chaos of association'. Going on to defend connectionism against Fodor and critics of passive mental representations, he shows how problems of the self are implicated in cognitive science. (shrink)

This essay frames systemic patterns of mental abuse against women of color and Indigenous women on Turtle Island (North America) in terms of larger design-of-distribution strategies in settler colonial societies, as these societies use various forms of social power to distribute, reproduce, and automate social inequalities (including public health precarities and mortality disadvantages) that skew socio-economic gain continuously toward white settler populations and their descendants. It departs from traditional studies in gender-based violence research that frame mental abuses such as gaslighting--commonly (...) understood as mental manipulation through lying or deceit--stochastically, as chance-driven interpersonal phenomena. Building on structural analyses of knowledge in political epistemology (Dotson 2012, Berenstain 2016), political theory (Davis and Ernst 2017), and Indigenous social theory (Tuck and Yang 2012), I develop the notion of cultural gaslighting to refer to the social and historical infrastructural support mechanisms that disproportionately produce abusive mental ambients in settler colonial cultures in order to further the ends of cultural genocide and dispossession. I conclude by proposing a social epidemiological account of gaslighting that a) highlights the public health harms of abusive ambients for minority populations, b) illuminates the hidden rules of social structure in settler colonial societies, and c) amplifies the corresponding need for structural reparations. (shrink)

Are there virtues that constitutively involve using certain concepts? Does it make sense to speak of rights or duties to use certain concepts? And do consequentialist approaches to concepts necessarily have to reproduce the difficulties that plague utilitarianism? These are fundamental orientating questions for the emerging field of conceptual ethics, which invites us to reflect critically about which concepts to use. In this article, I map out and explore the ways in which conceptual ethics might take its cue from virtue-ethical, (...) deontological, and consequentialist traditions of ethical thought, flagging the main difficulties facing each approach. I end by sketching how the various dimensions of evaluation singled out by these three traditions might be combined in a single approach. (shrink)

The replication crisis has caused researchers to distinguish between exact replications, which duplicate all aspects of a study that could potentially affect the results, and direct replications, which duplicate only those aspects of the study that are thought to be theoretically essential to reproduce the original effect. The replication crisis has also prompted researchers to think more carefully about the possibility of making Type I errors when rejecting null hypotheses. In this context, the present article considers the utility of two (...) types of Type I error probability: the Neyman–Pearson long run Type I error rate and the Fisherian sample-specific Type I error probability. It is argued that the Neyman–Pearson Type I error rate is inapplicable in social science because it refers to a long run of exact replications, and social science deals with irreversible units that make exact replications impossible. Instead, the Fisherian sample-specific Type I error probability is recommended as a more meaningful way to conceptualize false positive results in social science because it can be applied to each sample-specific decision about rejecting the same substantive null hypothesis in a series of direct replications. It is concluded that the replication crisis may be partly due to researchers’ unrealistic expectations about replicability based on their consideration of the Neyman–Pearson Type I error rate across a long run of exact replications. (shrink)

This classic collection of essays, first published in 1968, represents H.L.A. Hart's landmark contribution to the philosophy of criminal responsibility and punishment. Unavailable for ten years, this new edition reproduces the original text, adding a new critical introduction by John Gardner, a leading contemporary criminal law theorist.

Does the recent success of Podemos and Syriza herald a new era of inclusive, egalitarian left populism? Because leaders of both parties are former students of Ernesto Laclau and cite his account of populism as guiding their political practice, this essay considers whether his theory supports hope for a new kind of populism. For Laclau, the essence of populism is an “empty signifier” that provides a means by which anyone can identify with the people as a whole. However, the concept (...) of the empty signifier is not as neutral as he assumes. As I show by analyzing the role of race in his theory, some subjects are constituted in a way that prevents their unmediated identification with the people. Consequently, Laclau’s view should be read as symptomatic of the problems with populist logic if its adherents are to avoid reproducing its exclusions and practice a more inclusive politics. (shrink)

Abstract: Smoke detectors are critical devices for early fire detection and life-saving interventions. This research paper explores the application of Artificial Neural Networks (ANNs) in smoke detection systems. The study aims to develop a robust and accurate smoke detection model using ANNs. Surprisingly, the results indicate a 100% accuracy rate, suggesting promising potential for ANNs in enhancing smoke detection technology. However, this paper acknowledges the need for a comprehensive evaluation beyond accuracy. It discusses potential challenges, such as overfitting, dataset size, (...) and class imbalance, and presents strategies employed to address these issues. Additionally, the paper emphasizes the importance of alternative evaluation metrics, including precision, recall, and F1-score, to assess the model's performance comprehensively. Detailed information regarding the model architecture, data preprocessing, and hyperparameter tuning is provided to enhance the reproducibility of the research. The study also discusses ethical considerations and the implications of false positives and false negatives in smoke detection applications. While achieving 100% accuracy is a notable accomplishment, this paper calls for cautious interpretation and further validation in real-world settings. It concludes by highlighting areas for future research and improvement in smoke detection technology, emphasizing the need for practical deployment and the reduction of false alarms. (shrink)

This paper introduces the reconstitutor as a comprehensive unit of heredity within the context of evolutionary research. A reconstitutor is the structure resulting from a set of relationships between different elements or processes that are actively involved in the recreation of a specific phenotypic variant in each generation regardless of the biomolecular basis of the elements or whether they stand in a continuous line of ancestry. Firstly, we justify the necessity of introducing the reconstitutor by showing the limitations of other (...) evolutionary conceptions of the unit of heredity, such as the replicator, the reproducer, and the Darwinian individual. We argue that these conceptions are based on the requirement of lineage formation, which we argue to be unnecessary for the existence of evolutionary heredity. In the second part, we introduce the reconstitutor, which we base on the concept of Stability of Traits, and illustrate how it covers cases of hereditary phenomena not covered by the previous accounts. Secondly, we illustrate how the reconstitutor could serve as a platform to rethink ecological inheritance and other forms of inheritance that have been recently introduced under the song/singer model of evolution. (shrink)

This article offers an account and defence of constructionism, both as a metaphilosophical approach and as a philosophical methodology, with references to the so-called maker's knowledge tradition. Its main thesis is that Plato's “user's knowledge” tradition should be complemented, if not replaced, by a constructionist approach to philosophical problems in general and to knowledge in particular. Epistemic agents know something when they are able to build (reproduce, simulate, model, construct, etc.) that something and plug the obtained information into the correct (...) network of relations that account for it. Their epistemic expertise increases with the scope and depth of the questions that they are able to ask and answer. Thus, constructionism deprioritises mimetic, passive, and declarative knowledge that something is the case, in favour of poietic, interactive, and practical knowledge of something being the case. Metaphilosophically, constructionism suggests adding conceptual engineering to conceptual analysis as a fundamental method. (shrink)

I develop a phenomenological account of racialized encounters with works of art and film, wherein the racialized viewer feels cast as perpetually past, coming “too late” to intervene in the meaning of her own representation. This points to the distinctive role that the colonial past plays in mediating and constructing our self-images. I draw on my experience of three exhibitions that take Muslims and/or Arabs as their subject matter and that ostensibly try to interrupt or subvert racialization while reproducing some (...) of its tropes. My examples are the Jean-Joseph Benjamin-Constant exhibition at the Montreal Museum of Fine Arts (2015), the exposition Welten der Muslime at the Ethnologisches Museum in Berlin (2011–2017), and a sculpture by Bob and Roberta Smith at the Leeds City Art Gallery, created in response to the imperial power painting, General Gordon’s Last Stand, that is housed there. My interest is in how artworks contribute to the experience of being racialized in ways that not only amplify the circulation of images but also constitute difficult temporal relations to images. Drawing on Frantz Fanon’s Black Skin, White Masks, I argue that such racialized images are temporally gluey, or stuck, so that we are weighted and bogged down by them. This essay received Honorable Mention from the American Society for Aesthetics Feminist Caucus Committee in the Feminist Research Essay prize in 2020. (shrink)

There is a certain metaphor that has enjoyed tremendous longevity in the evolution of ageing literature. According to this metaphor, nature has a certain goal or purpose, the perpetuation of the species, or, alternatively, the reproductive success of the individual. In relation to this goal, the individual organism has a function, job, or task, namely, to breed and, in some species, to raise its brood to maturity. On this picture, those who cannot, or can no longer, reproduce are somehow invisible (...) to, or even dispensable to, the evolutionary process. Here, I argue that the metaphor should be discarded, not on the grounds that it is a metaphor, but on the grounds that this particular metaphor distorts our understanding of the evolution of ageing. One reason the metaphor is problematic is that it frames senescence and death as nature’s verdict on the value of older individuals. Instead, we should explore a different metaphor: the lengthy post-reproductive period in humans and some other animals is not an accident of culture, but designed by nature for the purpose of supporting and guiding younger generations. On this alternate picture, different stages of life have their own evolutionary rationales, their distinctive design features, their special mandates. (shrink)

Theoretical accounts of development exhibit several internal tensions and face multiple challenges. They span from the problem of the identification of the temporal boundaries of development (beginning and end) to the characterization of the distinctive type of change involved compared to other biological processes. They include questions such as the role to ascribe to the environment or what types of biological systems can undergo development and whether they should include colonies or even ecosystems. In this chapter we discuss these conceptual (...) issues, and we argue that adopting an organizational approach may help solve or clarify them. -/- While development is usually identified with the achievement of an adult form with the capability to reproduce and therefore maintain a lineage, adopting the organizational approach may provide a different strategy, which focuses also on the maintenance of the current organization of the organism. By doing so an organizational approach favors a switch in perspective which consists in analyzing how organisms maintain their viability at each moment of development rather than considering them as going through intermediate stages of a process directed toward a specific goal state. This developmental dimension of biological organization has yet to be given a general and detailed analysis within the organizational theoretical perspective, apart from some preliminary attempts. How a biological organization is maintained through a series of radical organizational changes and what these changes are issues that still require clarification. In this chapter we offer the beginnings of such an analysis of developmental transitions, understood as changes in functionality brought forth by regulatory mechanisms in the context of the continued maintenance of organizational viability at every step. (shrink)

The question of the holistic structure of an organism is a recurring theme in the philosophy of biology and has been increasingly discussed again in recent years. Organisms have recently been described as complex systems that autonomously create, maintain and reproduce themselves while constantly interacting with their environment. Key focal points include their autopoiesis, autonomy, agency and teleological structure. This perspective marks a significant advancement from the 20th-century viewpoint, which predominantly saw organisms as genetically programmed, randomly generated and blindly selected (...) survival-machines. However, crucial questions about the shape and development of organisms still lack answers. Shape and development are deeply interconnected and seem to require a holistic approach. Here, I will briefly outline a phenomenological perspective which could provide a framework for seeking answers to these fundamental questions. In particular, I propose a common four-fold phenomenal structure of the developing organism and the cognising consciousness, which makes it possible to observe the agential and teleological structure of the organism "from within". This fourfold structure also describes the molecular level and thus provides a general organismic concept. It furthermore corresponds to the four Aristotelian "causes" (conditions). (shrink)

Clade selection is unpopular with philosophers who otherwise accept multilevel selection theory. Clades cannot reproduce, and reproduction is widely thought necessary for evolution by natural selection, especially of complex adaptations. Using microbial evolutionary processes as heuristics, I argue contrariwise, that (1) clade growth (proliferation of contained species) substitutes for clade reproduction in the evolution of complex adaptation, (2) clade-level properties favoring persistence – species richness, dispersal, divergence, and possibly intraclade cooperation – are not collapsible into species-level traits, (3) such properties (...) can be maintained by selection on clades, and (4) clade selection extends the explanatory power of the theory of evolution. (shrink)

In De Anima 2.4, Aristotle claims that nutritive soul encompasses two distinct biological functions: nutrition and reproduction. We challenge a pervasive interpretation which posits ‘nutrients’ as the correlative object of the nutritive capacity. Instead, the shared object of nutrition and reproduction is that which is nourished and reproduced: the ensouled body, qua ensouled. Both functions aim at preserving this object, and thus at preserving the form, life, and being of the individual organism. In each case, we show how Aristotle’s detailed (...) biological analysis supports this ontological argument. (shrink)

The surface grammar of reports such as ‘I have a pain in my leg’ suggests that pains are objects which are spatially located in parts of the body. We show that the parallel construction is not available in Mandarin. Further, four philosophically important grammatical features of such reports cannot be reproduced. This suggests that arguments and puzzles surrounding such reports may be tracking artefacts of English, rather than philosophically significant features of the world.

This paper shows that several live philosophical and scientific hypotheses – including the holographic principle and multiverse theory in quantum physics, and eternalism and mind-body dualism in philosophy – jointly imply an audacious new theory of free will. This new theory, "Libertarian Compatibilism", holds that the physical world is an eternally existing array of two-dimensional information – a vast number of possible pasts, presents, and futures – and the mind a nonphysical entity or set of properties that "read" that physical (...) information off to subjective conscious awareness (in much the same way that a song written on an ordinary compact-disc is only played when read by an outside medium, i.e. a CD-player). According to this theory, every possible physical “timeline” in the multiverse may be fully physically deterministic or physically-causally closed but each person’s consciousness still entirely free to choose, ex nihilo, outside of the physical order, which physically-closed timeline is experienced by conscious observers. Although Libertarian Compatibilism is admittedly fantastic, I show that it not only follows from several live scientific and philosophical hypotheses, I also show that it (A) is a far more explanatorily powerful model of quantum mechanics than more traditional interpretations (e.g. the Copenhagen, Everett, and Bohmian interpretations), (B) makes determinate, testable empirical predictions in quantum theory, and finally, (C) predicts and explains the very existence of a number of philosophical debates and positions in the philosophy of mind, time, personal identity, and free will. First, I show that whereas traditional interpretations of quantum mechanics are all philosophically problematic and roughly as ontologically “extravagant” as Libertarian Compatibilism – in that they all posit “unseen” processes – Libertarian Compatibilism is nearly identical in structure to the only working simulation that human beings have ever constructed capable of reproducing (and so explaining) every general feature of quantum mechanics we perceive: namely, massive-multiplayer-online-roleplaying videogames (or MMORPGs). Although I am not the first to suggest that our world is akin to a computer simulation, I show that existing MMORPGs (online simulations we have already created) actually reproduce every general feature of quantum mechanics within their simulated-world reference-frames. Second, I show that existing MMORPGs also replicate (and so explain) many philosophical problems we face in the philosophy of mind, time, personal identity, and free will – all while conforming to the Libertarian Compatibilist model of reality. -/- I conclude, as such, that as fantastic and metaphysically extravagant as Libertarian Compatibilism may initially seem, it may well be true. It explains a number of features of our reality that no other physical or metaphysical theory does. (shrink)

Metaphors allow us to come to terms with abstract and complex information, by comparing it to something which is structured, familiar and concrete. Although modern science is “iconoclastic”, as Gaston Bachelard phrases it, scientists are at the same time prolific producers of metaphoric images themselves. Synthetic biology is an outstanding example of a technoscientific discourse replete with metaphors, including textual metaphors such as the “Morse code” of life, the “barcode” of life and the “book” of life. This paper focuses on (...) a different type of metaphor, however, namely on the archetypal metaphor of the mandala as a symbol of restored unity and wholeness. Notably, mandala images emerge in textual materials related to one of the new “frontiers” of contemporary technoscience, namely the building of a synthetic cell: a laboratory artefact that functions like a cell and is even able to replicate itself. The mandala symbol suggests that, after living systems have been successfully reduced to the elementary building blocks and barcodes of life, the time has now come to put these fragments together again. We can only claim to understand life, synthetic cell experts argue, if we are able to technically reproduce a fully functioning cell. This holistic turn towards the cell as a meaningful whole also requires convergence at the “subject pole”: the building of a synthetic cell as a practice of the self, representing a turn towards integration, of multiple perspectives and various forms of expertise. (shrink)

Many neurodegenerative and neuropsychiatric diseases and other brain disorders are accompanied by impairments in high-level cognitive functions including memory, attention, motivation, and decision-making. Despite several decades of extensive research, neuroscience is little closer to discovering new treatments. Key impediments include the absence of validated and robust cognitive assessment tools for facilitating translation from animal models to humans. In this review, we describe a state-of-the-art platform poised to overcome these impediments and improve the success of translational research, the Mouse Translational Research (...) Accelerator Platform (MouseTRAP), which is centered on the touchscreen cognitive testing system for rodents. It integrates touchscreen-based tests of high-level cognitive assessment with state-of-the art neurotechnology to record and manipulate molecular and circuit level activity in vivo in animal models during human-relevant cognitive performance. The platform also is integrated with two Open Science platforms designed to facilitate knowledge and data-sharing practices within the rodent touchscreen community, touchscreencognition and mousebytes. Touchscreencognition includes the Wall, showcasing touchscreen news and publications, the Forum, for community discussion, and Training, which includes courses, videos, SOPs, and symposia. To get started, interested researchers simply create user accounts. We describe the origins of the touchscreen testing system, the novel lines of research it has facilitated, and its increasingly widespread use in translational research, which is attributable in part to knowledge-sharing efforts over the past decade. We then identify the unique features of MouseTRAP that stand to potentially revolutionize translational research, and describe new initiatives to partner with similar platforms such as McGill’s M3 platform. (shrink)

A growing awareness of the lack of reproducibility has undermined society’s trust and esteem in social sciences. In some cases, well-known results have been fabricated or the underlying data have turned out to have weak technical foundations.

Attempts to reproduce animateness using appliances generates a paradox that provides a new view to life and death, that differs from both religious and atheistic visions.

Artificial Intelligence is at a turning point, with a substantial increase in projects aiming to implement sophisticated forms of human intelligence in machines. This research attempts to model specific forms of intelligence through brute-force search heuristics and also reproduce features of human perception and cognition, including emotions. Such goals have implications for artificial consciousness, with some arguing that it will be achievable once we overcome short-term engineering challenges. We believe, however, that phenomenal consciousness cannot be implemented in machines. This becomes (...) clear when considering emotions and examining the dissociation between consciousness and attention in humans. While we may be able to program ethical behavior based on rules and machine learning, we will never be able to reproduce emotions or empathy by programming such control systems—these will be merely simulations. Arguments in favor of this claim include considerations about evolution, the neuropsychological aspects of emotions, and the dissociation between attention and consciousness found in humans. Ultimately, we are far from achieving artificial consciousness. (shrink)