Non-deterministic matrices, a natural generalization of many-valued matrices, are semantic structures in which the value assigned to a complex formula may be chosen non-deterministically from a given set of options. We show that by combining non-deterministic matrices and distance-based considerations, one obtains a family of logics that are useful for reasoning with uncertainty. These logics are a conservative extension of those that are obtained by standard distance-based semantics, and so usual distance-based methods are easily simulated within our framework. We investigate (...) the basic properties of the distance-preferential non-deterministic logics, consider their application for reasoning with incomplete and inconsistent information, and show the correspondence between some particular entailments in our framework and well-known problems like max-SAT. (shrink)