James B. Ashbrook's "new natural theology in an empirical mode" pursued an integrated understanding of the spiritual, psychological, and neurological dimensions of spiritual life. Knowledge of neuroscience and personality theory was central to his quest, and his understandings were necessarily revised and amplified as scientific findings emerged. As a result, Ashbrook's legacy may serve as a case example of how to do religion-and-science in a milieu of scientific change. The constant in the quest was Ashbrook's core belief in the basic (...) holism of brain, mind, personality, the nature of reality, and the underlying reality of God. (shrink)