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Molecules, systems, and behavior: Another view of memory consolidation

In John Bickle (ed.), The Oxford Handbook of Philosophy and Neuroscience (2009)

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  1. Laser Lights and Designer Drugs: New Techniques for Descending Levels of Mechanisms “in a Single Bound”?John Bickle - 2020 - Topics in Cognitive Science 12 (4):1241-1256.
    Optogenetics and DREADDs (Designer Receptors Exclusively Activated by Designer Drugs) are important research tools in recent neurobiology. These tools allow unprecedented control over activity in specifically targeted neurons in behaving animals. Two approaches in philosophy of neuroscience, mechanism and ruthless reductionism, provide explicit accounts of experiments and results using tools like these, but each offers a different picture about how levels of mechanisms relate. I argue here that the ruthless reductionist’s direct mind‐to‐cellular/molecular activities linkages “in a single bound” better fits (...)
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  • Has the last decade of challenges to the multiple realization argument provided aid and comfort to psychoneural reductionists?John Bickle - 2010 - Synthese 177 (2):247 - 260.
    The previous decade has seen renewed critical interest in the multiple realization argument. These criticisms constitute a "second wave" of challenges to this central argument in late-20th century philosophy of mind. Unlike the first wave, which challenged the premise that multiple realization is inconsistent with reduction or type identity, this second wave challenges the truth of the multiple realization premise itself. Since psychoneural reductionism was prominent among the explicit targets of the multiple realization argument, one might think that this second (...)
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  • Introduction to “The Material Bases of Cognition”.Kenneth Aizawa - 2013 - Minds and Machines 23 (3):277-286.
    Special Issue: The Material Bases of Cognition Guest Editors: Fred Adams · Kenneth Aizawa -/- Compositional Explanatory Relations and Mechanistic Reduction K.L. Theurer 287 -/- Constitution, and Multiple Constitution, in the Sciences: Using the Neuron to Construct a Starting Framework C. Gillett 309 -/- The Mark of the Cognitive F. Adams · R. Garrison 339 -/- Dynamics and Cognition L.A. Shapiro 353 -/- Causal Parity and Externalisms: Extensions in Life and Mind P. Huneman 377 -/- Did I Do That? Brain–Computer (...)
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  • Seventeenth-Century Mechanism: An Alternative Framework for Reductionism.Kari L. Theurer - 2013 - Philosophy of Science 80 (5):907-918.
    The current antireductionist consensus rests in part on the indefensibility of the deductive-nomological model of explanation, on which classical reductionism depends. I argue that the DN model is inessential to the reductionist program and that mechanism provides a better framework for thinking about reductionism. This runs counter to the contemporary mechanists’ claim that mechanism is an alternative to reductionism. I demonstrate that mechanists are committed to reductionism, as evidenced by the historical roots of the contemporary mechanist program. This view shares (...)
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  • “Looking Up” and “Looking Down”: On the Dual Character of Mechanistic Explanations.Kari L. Theurer - 2018 - Journal for General Philosophy of Science / Zeitschrift für Allgemeine Wissenschaftstheorie 49 (3):371-392.
    Mechanistic explanation is at present the received view of scientific explanation. One of its central features is the idea that mechanistic explanations are both “downward looking” and “upward looking”: they explain by offering information about the internal constitution of the mechanism as well as the larger environment in which the mechanism is situated. That is, they offer both constitutive and contextual explanatory information. Adequate mechanistic explanations, on this view, accommodate the full range of explanatory factors both “above” and “below” the (...)
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  • Compositional Explanatory Relations and Mechanistic Reduction.Kari L. Theurer - 2013 - Minds and Machines 23 (3):287-307.
    Recently, some mechanists have embraced reductionism and some reductionists have endorsed mechanism. However, the two camps disagree sharply about the extent to which mechanistic explanation is a reductionistic enterprise. Reductionists maintain that cellular and molecular mechanisms can explain mental phenomena without necessary appeal to higher-level mechanisms. Mechanists deny this claim. I argue that this dispute turns on whether reduction is a transitive relation. I show that it is. Therefore, mechanistic explanations at the cellular and molecular level explain mental phenomena. I (...)
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  • Realization, explanation and the mind-body relation: Editor’s introduction.Jacqueline A. Sullivan - 2010 - Synthese 177 (2):151-164.
    This volume brings together a number of perspectives on the nature of realization explanation and experimentation in the ‘special’ and biological sciences as well as the related issues of psychoneural reduction and cognitive extension. The first two papers in the volume may be regarded as offering direct responses to the questions: (1) What model of realization is appropriate for understanding the metaphysics of science? and (2) What kind of philosophical work is such a model ultimately supposed to do?
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  • Reconsidering 'spatial memory' and the Morris water maze.Jacqueline Anne Sullivan - 2010 - Synthese 177 (2):261-283.
    The Morris water maze has been put forward in the philosophy of neuroscience as an example of an experimental arrangement that may be used to delineate the cognitive faculty of spatial memory (e.g., Craver and Darden, Theory and method in the neurosciences, University of Pittsburgh Press, Pittsburgh, 2001; Craver, Explaining the brain: Mechanisms and the mosaic unity of neuroscience, Oxford University Press, Oxford, 2007). However, in the experimental and review literature on the water maze throughout the history of its use, (...)
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  • Psychoneural reduction: a perspective from neural circuits.David Parker - 2019 - Biology and Philosophy 34 (4):44.
    Psychoneural reduction has been debated extensively in the philosophy of neuroscience. In this article I will evaluate metascientific approaches that claim direct molecular and cellular explanations of cognitive functions. I will initially consider the issues involved in linking cellular properties to behaviour from the general perspective of neural circuits. These circuits that integrate the molecular and cellular components underlying cognition and behaviour, making consideration of circuit properties relevant to reductionist debates. I will then apply this general perspective to specific systems (...)
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  • Methodological considerations for the mechanistic explanation of illusory representations in the context of psychopathology.Farshad Nemati - forthcoming - Phenomenology and the Cognitive Sciences:1-25.
    A mechanistic explanation is a desired outcome in many studies of perception. Such explanations require discovering the processes that contribute to the realization of a perceptual phenomenon at different levels of information processing. The present analysis aims at investigating the obstacles to develop such mechanistic explanations and their potential solutions in the context of psychopathology. Geometric-Optical Illusions (GOIs) are among perceptual phenomena that have been studied to understand psychopathology in various clinical populations. In the present analysis, the GOIs will be (...)
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  • What’s on Your Mind? A Brain Scan Won’t Tell.Yakir Levin & Itzhak Aharon - 2011 - Review of Philosophy and Psychology 2 (4):699-722.
    Reverse Inference ( RI ) is an imaging-based type of inference from brain states to mental states, which has become highly widespread in neuroscience, most especially in neuroeconomics. Recent critical studies of RI may be taken to show that, if cautiously used, RI can help achieve research goals that may be difficult to achieve by way of behavior-based procedures alone. But can RI exceed the limits of these procedures and achieve research goals that are impossible for them to achieve alone? (...)
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  • Multiple realizability.John Bickle - 2008 - Stanford Encyclopedia of Philosophy.
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  • Diachronic Metaphysical Building Relations: Towards the Metaphysics of Extended Cognition.Michael David Kirchhoff - 2013 - Dissertation, Macquarie University
    In the thesis I offer an analysis of the metaphysical underpinnings of the extended cognition thesis via an examination of standard views of metaphysical building (or, dependence) relations. -/- In summary form, the extended cognition thesis is a view put forth in naturalistic philosophy of mind stating that the physical basis of cognitive processes and cognitive processing may, in the right circumstances, be distributed across neural, bodily, and environmental vehicles. As such, the extended cognition thesis breaks substantially with the still (...)
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  • Structuralist Contributions – and Limitations? – to the Study of Scientific Reduction.John Bickle - 2012 - Metatheoria – Revista de Filosofía E Historia de la Ciencia 2:1--23.
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  • Pain is Mechanism.Simon van Rysewyk - 2013 - Dissertation, University of Tasmania
    What is the relationship between pain and the body? I claim that pain is best explained as a type of personal experience and the bodily response during pain is best explained in terms of a type of mechanical neurophysiologic operation. I apply the radical philosophy of identity theory from philosophy of mind to the relationship between the personal experience of pain and specific neurophysiologic mechanism and argue that the relationship between them is best explained as one of type identity. Specifically, (...)
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  • Researching vs. Reifying Race: The Case of Obesity Research.Koffi N. Maglo & Lisa J. Martin - 2012 - Humana Mente 5 (22).
    This paper deals with the reification of the concept of race in biomedical research. It combines philosophical analysis and a quantitative approach to investigate the ways in which the reification fallacy may occur in race research, thereby providing theoretical legitimacy to the misuse of scientific research. It examines the prevalence of obesity in the US and some African countries as an empirical case to guide a conceptual analysis. The paper suggests that, to avoid the reification of race, researchers need to (...)
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