This essay is a historical–geographical account of how scientists and public health officials conceptualized and assessed northern radioactive exposures in the late 1950s and 1960s. The detection of radionuclides in caribou bodies in northern Canada both demonstrated the global reach of nuclear fallout and revealed the unevenness of toxic relations and radioactive exposures. Following the documentation of the lichen–caribou–human pathway of exposure, Canadian public health officials became increasingly concerned about the possibility of heightened radioactive exposures among Indigenous northerners. Between 1963 (...) and 1969, scientists and officials with Canada’s Radiation Protection Division coordinated an interdepartmental monitoring program through which they sought to determine whether the consumption of contaminated caribou meat had caused radioactive exposure levels in northern communities to exceed the officially recognized “safe limits.” In 1969, the northern monitoring program was suspended after officials determined that radionuclide body burdens had not exceeded the threshold for radioactive exposures. While the RPD emphasized its development of a technoscientific approach to measuring radioactive body burdens, the legitimacy of the monitoring program was linked directly to interdepartmental relations within Canada’s colonial northern administration. I situate the northern monitoring program within broader shifts in public health approaches to radiation protection and use Gabrielle Hecht’s concept of nuclearity to demonstrate how RPD officials employed the logic of the threshold in their assessment of radioactive exposures. (shrink)

Ruth Myrtle Patrick was a pioneering ecologist and taxonomist whose extraordinary career at the Academy of Natural Sciences of Philadelphia spanned over six decades. In 1947, an opportunity arose for Patrick to lead a new kind of river survey for the Pennsylvania Sanitary Water Board to study the effects of pollution on aquatic organisms. Patrick leveraged her already extensive scientific network, which included ecologist G. Evelyn Hutchinson, to overcome resistance within the Academy, establish a new Department of Limnology, and carry (...) out the survey, which was a resounding success and brought much needed money to the Academy. As demand for her expertise grew among industrial companies, such as the chemical company DuPont, Patrick became more active in the world of applied science. She repurposed data and instruments from her river surveys to run new experiments, test ecological theories, and conduct long-term ecological studies. Through these studies, she advanced an argument that biologist Thomas Lovejoy dubbed the “Patrick principle,” the idea that the ecological health of a body of water could be measured by the relative abundance and diversity of species living there. Patrick was elected to the National Academy of Sciences in 1970, became a board member of DuPont in 1975, and received two of the most prestigious awards in ecology: the Eminent Ecologist Award from the Ecological Society of America in 1972 and the Tyler Ecology Award in 1975. This article analyzes Patrick’s unusual success in bridging the worlds of science and industry and her unusual ability to cross, and redefine, the perceived boundary between basic and applied fields in biology. It argues that Patrick’s position at the Academy, an institution of natural history that was both willing and able to accept money from industrial corporations, is key to understanding her success in, and influence on, the field of river ecology. (shrink)

The widespread adoption of radioisotopes as tools in biomedical research and therapy became one of the major consequences of the "physicists' war" for postwar life science. Scientists in the Manhattan Project, as part of their efforts to advocate for civilian uses of atomic energy after the war, proposed using infrastructure from the wartime bomb project to develop a government-run radioisotope distribution program. After the Atomic Energy Bill was passed and before the Atomic Energy Commission was formally established, the Manhattan Project (...) began shipping isotopes from Oak Ridge. Scientists and physicians put these reactor-produced isotopes to many of the same uses that had been pioneered with cyclotron-generated radioisotopes in the 1930s and early 1940s. The majority of early AEC shipments were radioiodine and radiophosphorus, employed to evaluate thyroid function, diagnose medical disorders, and irradiate tumors. Both researchers and politicians lauded radioisotopes publicly for their potential in curing diseases, particularly cancer. However, isotopes proved less successful than anticipated in treating cancer and more successful in medical diagnostics. On the research side, reactor-generated radioisotopes equipped biologists with new tools to trace molecular transformations from metabolic pathways to ecosystems. The U.S. government's production and promotion of isotopes stimulated their consumption by scientists and physicians, such that in the postwar period isotopes became routine elements of laboratory and clinical use. In the early postwar years, radioisotopes signified the government's commitment to harness the atom for peace, particularly through contributions to biology, medicine, and agriculture. (shrink)

This article explores the problem of the foundation of the European Molecular Biology Organization, by reconstructing a broader institutional framework, which includes other international actors – EURATOM, UNESCO and the International Laboratory of Genetics and Biophysics in Naples – and a relevant, but still neglected figure, the Italian geneticist Adriano Buzzati-Traverso. The article considers the tension between centralized and federal models of organization in the field of life sciences not just as an EMBO internal controversy, but rather as a structural (...) issue of European scientific cooperation in fundamental biology in the early 1960s. Along with EMBO, the article analyzes in particular the EURATOM Biology Division Program and the constitution of UNESCO International Cell Research Organization. Adriano Buzzati-Traverso, as founder of ILGB and scientific consultant of EURATOM and UNESCO, played a crucial role in the complex negotiation which ultimately led to the foundation of EMBO. A synchronic treatment of ILGB, EURATOM, UNESCO-ICRO and EMBO opens a window on the early 1960s institutional configuration of molecular biology in Europe, showing how it basically incorporated the “Cold Spring Harbor” decentralized model rather than reproducing the “CERN” centralized model. (shrink)