This paper explores the consequences of transhumanism on free will based on the metaphysical aspect of the Botho perspective. Botho is an indigenous philosophy, prominent in Botswana, that expresses the essence of being a person. A human person from the Botho metaphysical point of view embodies material and immaterial aspects. This study seeks to answer the question: “Would certain transhuman changes to the material body affect the human person’s ability to judge and choose and hence the capacity for free will?” (...) According to the Botho perspective, determinism and free will would be compatible in unenhanced human beings. From this viewpoint, human beings are free insofar as they can act in accordance with reason, which is a determined process. This framework will be applied to hypothetically enhanced human beings and argue that transhumanism does not necessarily undermine free will. This study will also show that some forms of biotechnological enhancement could in fact improve free will, while other forms could limit free will without eliminating it. New knowledge will be gained by applying a prominent metaphysical orientation in the Botho worldview, particularly its discussion of determinism and free will, to the debate about enhancements. It will be demonstrated that most Africans, including Batswana, are soft determinists who embrace both determinism and free will so that they are not incompatible and can co-exist. (shrink)