This article investigates the anthropology of Spinoza as a strategy for happiness, political, as well as individual. Inspired by the readings, comments, and perspectives of Matheron, Deleuze, and Balibar, I will analyze Spinoza’s theory of the affects as the basis for this strategic anthropology. These authors all share an ontological and political vision organized around the concepts of multitude and the transindividual which result directly from Spinoza’s analysis of the human affects in books III and IV of the Ethics, and (...) his theory of political dynamics developed in the Political treatise. They consider Spinoza a contemporary and share with him the idea of a relational ontology and an inextricable and mutual interdependence of the individual and the community which is captured in the concept of the transindividual. With Matheron/Spinoza I will focus on the question of anthropology and the structure of thought, with Deleuze/Spinoza on the kinds of knowledge in relation to the human mind and body, and with Balibar/Spinoza on the transindividual, productive, active, and thus strategic nature of our thinking. These three analyses of human thought and affects all proceed from the hypothesis of conatus/desire as human essence and aim not just at theoretical knowledge but rather at the effective improvement of our well-being and lives, that is, at happiness. (shrink)