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  1. A New Look at ‘Levels of Organization’ in Biology.Daniel S. Brooks - 2019 - Erkenntnis 86.
    Despite its pervasiveness, the concept of ‘levels of organization’ has received relatively little attention in its own right. I propose here an emerging approach that posits ‘levels’ as a fragmentary concept situated within an interest-relative matrix of operational usage within scientific practice. To this end I propose one important component of meaning, namely the epistemic goal motivating the term’s usage, which recovers a remarkably conserved and sufficiently unifying significance attributable to ‘levels’ across different instances of usage. This epistemic goal, to (...)
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  • Why is There No Successful Whole Brain Simulation (Yet)?Klaus M. Stiefel & Daniel S. Brooks - 2019 - Biological Theory 14 (2):122-130.
    With the advent of powerful parallel computers, efforts have commenced to simulate complete mammalian brains. However, so far none of these efforts has produced outcomes close to explaining even the behavioral complexities of animals. In this article, we suggest four challenges that ground this shortcoming. First, we discuss the connection between hypothesis testing and simulations. Typically, efforts to simulate complete mammalian brains lack a clear hypothesis. Second, we treat complications related to a lack of parameter constraints for large-scale simulations. To (...)
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  • Model-as-replica, model-as-instrument: Representational power and contextual versatility in animal models.Bican Polat - 2021 - Studies in History and Philosophy of Science Part A 89 (C):19-30.
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