Controversy over the possibility of detecting design in natural sciences: According to intelligent design theory, certain biological and cosmic phenomena are designed by an intelligent being and this design is scientifically detectable. However, critics refuse to regard this theory as scientific, thereby suggesting that it does not deserve serious discussion in scientific circles. The article presents main methodological objections to intelligent design theory, indicating its unscientific or pseudoscientific character and impossibility of scientific design detection. Critics try to show that this (...) theory: 1) violates the principle of methodological naturalism ; 2) is empirically untestable; 3) it does not invoke natural laws, says nothing about the designer and the designing mechanism; 4) it does not offer predictions; 5) it is an argument from ignorance, and 6) it does not lead to fruitful research program and hence is not useful for science. These objections will be analyzed from the perspective of methodological thesis of design theorists that the sufficient condition of design inference are the characteristic effects leaved by the activity of the designer, which indicate the final cause, although they do not have to be the basis for determining the designer’s identity. If this thesis is sound, then the objections that intelligent design theory is not scientific are rebutted or weakened. Moreover, it turns out that, basically, detecting design of supernatural beings does not differ from detecting design of natural beings. For that reason, there is no qualitative difference between these two procedures and both can be regarded as scientific. (shrink)