The physical concept of locality is first analyzed in the special relativistic quantum regime, and compared with that of microcausality and the local commutativity of quantum fields. Its extrapolation to quantum general relativity on quantum bundles over curved spacetime is then described. It is shown that the resulting formulation of quantum-geometric locality based on the concept of local quantum frame incorporating a fundamental length embodies the key geometric and topological aspects of this concept. Taken in conjunction with the strong equivalence (...) principle and the path-integral formulation of quantum propagation, quantum-geometric locality leads in a natural manner to the formulation of quantum-geometric propagation in curved spacetime. Its extrapolation to geometric quantum gravity formulated over quantum spacetime is described and analyzed. (shrink)