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  1. Beyond the oncogene paradigm: Understanding complexity in cancerogenesis.M. Bizzarri, A. Cucina, F. Conti & F. D’Anselmi - 2008 - Acta Biotheoretica 56 (3):173-196.
    In the past decades, an enormous amount of precious information has been collected about molecular and genetic characteristics of cancer. This knowledge is mainly based on a reductionistic approach, meanwhile cancer is widely recognized to be a ‘system biology disease’. The behavior of complex physiological processes cannot be understood simply by knowing how the parts work in isolation. There is not solely a matter how to integrate all available knowledge in such a way that we can still deal with complexity, (...)
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