After reviewing various natural bi-interpretations in urelement set theory, including second-order set theories with urelements, we explore the strength of second-order reflection in these contexts. Ultimately, we prove, second-order reflection with the abundant atom axiom is bi-interpretable and hence also equiconsistent with the existence of a supercompact cardinal. The proof relies on a reflection characterization of supercompactness, namely, a cardinal κ is supercompact if and only if every Π11 sentence true in a structure M (of any size) containing κ in (...) a language of size less than κ is also true in a substructure m≺M of size less than κ with m∩κ∈κ. (shrink)