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  1. A framework for the ethical assessment of chimeric animal research involving human neural tissue.Sebastian Porsdam Mann, Rosa Sun & Göran Hermerén - 2019 - BMC Medical Ethics 20 (1):10.
    Animal models of human diseases are often used in biomedical research in place of human subjects. However, results obtained by animal models may fail to hold true for humans. One way of addressing this problem is to make animal models more similar to humans by placing human tissue into animal models, rendering them chimeric. Since technical and ethical limitations make neurological disorders difficult to study in humans, chimeric models with human neural tissue could help advance our understanding of neuropathophysiology. In (...)
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  • Defining Dignity and Its Place in Human Rights.Lucy Michael - 2014 - The New Bioethics 20 (1):12-34.
    The concept of dignity is widely used in society, particularly in reference to human rights law and bioethics. Several conceptions of dignity are identified, falling broadly within two categories: full inherent dignity (FID) and non-inherent dignity (NID). FID is a quality belonging equally to every being with full moral status, including all members of the human natural kind; it is permanent, unconditional, indivisible and inviolable. Those beings with FID ought to be treated deferentially by others by virtue of their belonging (...)
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  • Human dignity and the creation of human–nonhuman chimeras.César Palacios-González - 2015 - Medicine, Health Care and Philosophy 18 (4):487-499.
    In this work I present a detailed critique of the dignity-related arguments that have been advanced against the creation of human–nonhuman chimeras that could possess human-like mental capacities. My main claim is that the arguments so far advanced are incapable of grounding a principled objection against the creation of such creatures. I conclude that these arguments have one, or more, of the following problems: they confuse the ethical assessment of the creation of chimeras with the ethical assessment of how such (...)
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  • Differentiating between human and non-human interspecies embryos.Calum MacKellar - 2014 - Journal of Medical Ethics 40 (4):284-285.
    Following the debate in the UK House of Lords, in December 2012, uncertainty remains as to the manner in which human and non-human interspecies embryos are differentiated in law.
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  • Ethical aspects of creating human–nonhuman chimeras capable of human gamete production and human pregnancy.César Palacios-González - 2015 - Monash Bioethics Review 33 (2-3):181-202.
    In this paper I explore some of the moral issues that could emerge from the creation of human–nonhuman chimeras capable of human gamete production and human pregnancy. First I explore whether there is a cogent argument against the creation of HNH-chimeras that could produce human gametes. I conclude that so far there is none, and that in fact there is at least one good moral reason for producing such types of creatures. Afterwards I explore some of the moral problems that (...)
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  • Books received. [REVIEW]Roberto Andorno - 2013 - Medicine, Health Care and Philosophy 16 (1):121-121.
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