An increased focus on fake news and misinformation is currently emerging. But what does it mean when information is designated as “fake?” Research on deception has focused on lies of commission, in which people disclose something false as true. However, people can also lie by omission, by withholding important yet true information. In this research, we investigate when people are more likely to tell a lie of omission. In three studies, with tests among undergraduates, online sample respondents, and candidates for (...) U.S. Senate, we found that people in a gain frame were more likely to lie by omission (vs. commission), and vice versa for a loss frame. Moreover, participants rated lies of commission in a gain frame as the least acceptable type of deception, suggesting why people may avoid telling this kind of lie. Overall, our results emphasize that from frame-to-frame, lying is not only different in degree but different in kind. (shrink)