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  1. Can machine learning make naturalism about health truly naturalistic? A reflection on a data-driven concept of health.Ariel Guersenzvaig - 2023 - Ethics and Information Technology 26 (1):1-12.
    Through hypothetical scenarios, this paper analyses whether machine learning (ML) could resolve one of the main shortcomings present in Christopher Boorse’s Biostatistical Theory of health (BST). In doing so, it foregrounds the boundaries and challenges of employing ML in formulating a naturalist (i.e., prima facie value-free) definition of health. The paper argues that a sweeping dataist approach cannot fully make the BST truly naturalistic, as prior theories and values persist. It also points out that supervised learning introduces circularity, rendering it (...)
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  • Epistemic Value of Digital Simulacra for Patients.Eleanor Gilmore-Szott - 2023 - American Journal of Bioethics 23 (9):63-66.
    Artificial Intelligence and Machine Learning (AI/ML) models introduce unique considerations when determining their epistemic value. Fortunately, existing work on the epistemic features of AI/ML can...
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  • Enabling the Nonhypothesis-Driven Approach: On Data Minimalization, Bias, and the Integration of Data Science in Medical Research and Practice.C. W. Safarlou, M. van Smeden, R. Vermeulen & K. R. Jongsma - 2023 - American Journal of Bioethics 23 (9):72-76.
    Cho and Martinez-Martin provide a wide-ranging analysis of what they label “digital simulacra”—which are in essence data-driven AI-based simulation models such as digital twins or models used for i...
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  • AI-Based Medical Solutions Can Threaten Physicians’ Ethical Obligations Only If Allowed to Do So.Benjamin Gregg - 2023 - American Journal of Bioethics 23 (9):84-86.
    Mildred Cho and Nicole Martinez-Martin (2023) distinguish between two of the ways in which humans can be represented in medical contexts. One is technical: a digital model of aspects of a person’s...
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  • Care Depersonalized: The Risk of Infocratic “Personalised” Care and a Posthuman Dystopia.Matthew Tieu & Alison L. Kitson - 2023 - American Journal of Bioethics 23 (9):89-91.
    Much of the discussion of the role of emerging technologies associated with AI, machine learning, digital simulacra, and relevant ethical considerations such as those discussed in the target article, take a relatively narrow and episodic view of a person’s healthcare needs. There is much speculation about diagnostic, treatment, and predictive applications but relatively little consideration of how such technologies might be used to address a person’s lived experience of illness and ongoing care needs. This is likely due to the greater (...)
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  • Digital Simulacra and the Call for Epistemic Responsibility: An Ubuntu Perspective.Brandon Ferlito & Michiel De Proost - 2023 - American Journal of Bioethics 23 (9):91-93.
    Cho and Martinez-Martin (2023) discuss the ethical challenges associated with the use of digital simulacra (also known as digital twins) in biomedicine, specifically focusing on the issue of episte...
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  • In Their Own Image: Ethical Implications of the Rise of Digital Twins/Clones/Simulacra in Healthcare.Benjamin Amram, Uri Klempner, Yehuda Leibler & Dov Greenbaum - 2023 - American Journal of Bioethics 23 (9):79-81.
    Bioconvergence is a growing area within the evolving bioeconomy that seeks out synergistic opportunities at the intersection of engineering and the life sciences (Greenbaum 2023). One example is th...
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  • Individuals and (Synthetic) Data Points: Using Value-Sensitive Design to Foster Ethical Deliberations on Epistemic Transitions.Jean-Christophe Bélisle-Pipon, Vardit Ravitsky, Bridge2AI-Voice Consortium & Yael Bensoussan - 2023 - American Journal of Bioethics 23 (9):69-72.
    Cho and Martinez-Martin (2023) provide a compelling critique of the profound influence that data sourcing for artificial intelligence (AI) has on the healthcare sector. They emphasize the need for...
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  • Digital Simulacra: Circumventing Diversity and Inclusion.Benjamin Collins & Nora Jones - 2023 - American Journal of Bioethics 23 (9):76-78.
    Cho and Martinez-Martin’s (2023) “Epistemic rights and responsibilities of digital simulacra for biomedicine” presents a comprehensive overview of big data and AI in clinical medicine and research....
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  • Digital Simulacra Mark an Ontological Shift in Biomedicine with Far-Reaching Consequences for Real Patients.Hazar Haidar, Luyba Encheva & Kalina Kamenova - 2023 - American Journal of Bioethics 23 (9):81-84.
    Cho and Martinez-Martin (2023) provide a thoughtful analysis of the epistemological and ethical implications of digital twin (DT) technology in biomedical research. However, they overlook the profo...
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  • Health Digital Twins, Legal Liability, and Medical Practice.Andreas Kuersten - 2023 - American Journal of Bioethics 23 (9):66-69.
    Digital twins for health care have the potential to significantly impact the provision of medical services. In addition to possible use in care, this technology could serve as a conduit by which no...
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  • Navigating the Landscape of Digital Twins in Medicine: A Relational Bioethical Inquiry.Brandon Ferlito, Michiel De Proost & Seppe Segers - 2024 - Asian Bioethics Review 16 (3):471-481.
    This perspective article explores the use of digital twins (DTs) in medicine, highlighting its capacity to simulate risks and personalize treatments while examining the emerging bioethical concerns. Central concerns include power dynamics, exclusion, and misrepresentation. We propose adopting a relational bioethical approach that advocates for a comprehensive assessment of DTs in medicine, extending beyond individual interactions to consider broader structural relations and varying levels of access to power. This can be achieved through two key relational recommendations: acknowledging the impact of (...)
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  • Ethics, First.Melissa D. McCradden - 2023 - American Journal of Bioethics 23 (9):55-56.
    If you’ve ever had a time where your smartwatch buzzed to say you’ve completed your daily steps while you were actually just brushing your hair, you’ll know our data aren’t perfect. Every day, we c...
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  • Integrating Social Determinants of Health into Ethical Digital Simulations.Kristin Kostick-Quenet, Vasiliki Rahimzadeh, Sharmila Anandasabapathy, Meghan Hurley, Anika Sonig & Amy Mcguire - 2023 - American Journal of Bioethics 23 (9):57-60.
    In their article, Cho and Martinez-Martin (2023) argue that developers and users of digital simulacra for modelling health and disease should involve a continued focus on causality of health states...
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  • Should We be More Worried about Digital Simulacra in Healthcare Being Our “Caricatures,” Rather than Our “Replicas”?Brad Partridge - 2023 - American Journal of Bioethics 23 (9):86-88.
    The construction of digital simulacra in healthcare and medical research purportedly strives to virtually recreate some aspect of reality, whether that be a piece of human tissue, an entire organ,...
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  • Digital Simulacra, Bias, and Self-Reinforcing Exclusion Cycles.Ana Bracic & I. I. W. Nicholson Price - 2023 - American Journal of Bioethics 23 (9):60-63.
    Digital simulacra present an entrancing vision of a research-rich future shorn of the messiness that comes from dealing with real live patients as part of the research enterprise—and in that sheari...
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