Known to produce out-of-body states and profound changes in sensory perception, mood, and thought, DMT is a potent short-lasting tryptamine that has experienced growing appeal in the last decade, independent from ayahuasca, the Amazonian visionary brew in which it is an integral ingredient. Investigating user reports available online as well as a variety of other sources consulted in extended cultural research, this article focuses on the “breakthrough” event commonly associated with the DMT trance. The DMT breakthrough event coincides with significant (...) revelatory outcomes associated with perceived contact with “entities” and the transmission of information often in the form of visual language. Examination of the breakthrough event offers insight on the liminal phenomenology of DMT and other tryptamines, a liminality that is given primary expression in reported travels in “hyperspace.” The article examines user reports of DMT “hyperspace” observing a transitional process that, unlike conventional passage rites, is private, individualized, internal, and “ritual like.” As an exploratory discussion of an under-researched phenomenon, the article enters this virtual terrain through a discussion of the gnostic, therapeutic, and recreational modalities of DMT use, before exploring ritual-like modes of transmission and concluding with comments on the ontological significance of the DMT trance. (shrink)

Arguably the most remarkable property of the human brain is its ability to construct the world that appears to consciousness. The brain is capable of building worlds during waking life, but also in the complete absence of extrinsic sensory data, entirely from intrinsic thalamocortical activity, as during dreaming. DMT, an extraordinary psychedelic, perturbs brain activity such that indescribably bizarre and apparently alien worlds are built. This property of DMT continues to defy explanation. However, by regarding this unique molecule as equivalent (...) to serotonin, an endogenous neuromodulator with a long-standing relationship with the brain, DMT's effects may be explained. Serotonin has evolved to hold the brain's thalamocortical system in a state in which the consensus world is built. When serotonin is replaced by DMT, the thalamocortical system shifts into an equivalent state, but one in which an apparently alien world is built. This suggests that DMT may be an ancestral neuromodulator, at one time secreted endogenously in psychedelic concentrations-a function apparently now lost. However, DMT maintains a number of unique pharmacological characteristics and a peculiar affinity with the human brain that supports this model. Thus, the modern practice of ingesting exogenous DMT may be the reconstitution of an ancestral function. (shrink)