Several theologians have pointed to resonances between the Greek Patristic doctrine of deification or theosis and recent transhumanist narratives: both discourses indicate death as the final enemy of humankind and invest heavily in a hoped-for transcendence of life as we know it. These resonances will be investigated further by comparing the approach to human nature found in Maximus the Confessor and in the prominent transhumanists Nick Bostrom and John Harris. In addition to sharing with transhumanists a disavowal of death and (...) a trajectory towards transcendence, Maximus also shares a view of human nature that is more dynamic and open-ended than is commonly attributed to his Late Antique context. On the other hand, Maximus also insists on the persistence of this dynamic nature in its integrity even into the eschaton. He does so for a number of reasons that should give Christians pause about any rhetoric that calls for an abandonment of human nature: (1) that theosis depends precisely on sharing a human nature with Christ; (2) that our vocation as mediators in creation depends on our physical bodies as the locus of shared existence with the material world; and (3) that corruption has a providential use in binding us together with our neighbors and in cultivating virtue as we strain for the incorruptible and supernatural gift of theosis. (shrink)