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  1. Birth of the eukaryotes by a set of reactive innovations: New insights force us to relinquish gradual models.Dave Speijer - 2015 - Bioessays 37 (12):1268-1276.
    Of two contending models for eukaryotic evolution the “archezoan“ has an amitochondriate eukaryote take up an endosymbiont, while “symbiogenesis“ states that an Archaeon became a eukaryote as the result of this uptake. If so, organelle formation resulting from new engulfments is simplified by the primordial symbiogenesis, and less informative regarding the bacterium‐to‐mitochondrion conversion. Gradualist archezoan visions still permeate evolutionary thinking, but are much less likely than symbiogenesis. Genuine amitochondriate eukaryotes have never been found and rapid, explosive adaptive periods characteristic of (...)
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  • The first eukaryote cell: an unfinished history of contestation.Maureen A. O’Malley - 2010 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 41 (3):212-224.
    The eukaryote cell is one of the most radical innovations in the history of life, and the circumstances of its emergence are still deeply contested. This paper will outline the recent history of attempts to reveal these origins, with special attention to the argumentative strategies used to support claims about the first eukaryote cell. I will focus on two general models of eukaryogenesis: the phagotrophy model and the syntrophy model. As their labels indicate, they are based on claims about metabolic (...)
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  • Cognitive Cells: From Cellular Senomic Spheres to Earth’s Biosphere.František Baluška - forthcoming - Biological Theory:1-11.
    Cells are central for life, starting some 3.7 billion years ago with the assembly of the first primordial cells in the primeval and prebiotic oceans of the young Earth’s environment. Details of this abiogenesis are still missing but since the first competent, self-reproductive cell emerged, life has been based on continuous cell divisions. Accordingly, all present cells can be traced directly to the very first cells. Our senomic concept of cell sentience based on bioelectromagnetic fields postulated that all cells are (...)
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  • Acid digestion and symbiont: Proton sharing at the origin of mitochondriogenesis?Mario Mencía - 2023 - Bioessays 45 (1):2200136.
    The initial relationships between organisms leading to endosymbiosis and the first eukaryote are currently a topic of hot debate. Here, I present a theory that offers a gradual scenario in which the origins of phagocytosis and mitochondria are intertwined in such a way that the evolution of one would not be possible without the other. In this scenario, the premitochondrial bacterial symbiont became initially associated with a protophagocytic host on the basis of cooperation to kill prey with symbiont‐produced toxins and (...)
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  • On the Evolution of the Biological Framework for Insight.Claudio Neidhöfer - 2021 - Philosophies 6 (2):43.
    The details of abiogenesis, to date, remain a matter of debate and constitute a key mystery in science and philosophy. The prevailing scientific hypothesis implies an evolutionary process of increasing complexity on Earth starting from (self-) replicating polymers. Defining the cut-off point where life begins is another moot point beyond the scope of this article. We will instead walk through the known evolutionary steps that led from these first exceptional polymers to the vast network of living biomatter that spans our (...)
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