Johann Wolfgang von Goethe's approach to science is a radical departure from the Cartesian-Newtonian scientific framework and offers contemporary science a pathway toward the cultivation of an alternative approach to the study of the natural world. This paper argues that the Cartesian-Newtonian pathway is pathological because it has as its premise humanity's alienation from the natural world, which sets up a host of consequences that terminate in nihilism. As an alternative approach to science, Goethe's "delicate empiricism" begins with the premise (...) that humanity is fundamentally at home in the world: a notion which forms the basis for a Goethean science that gives primacy to perception, offers a more organic and holistic conception of the universe, and has as its goal the cultivation of aesthetic appreciation and morally responsive obligation to the observed. As an antidote to nihilism and as the basis for a more fulfilling and morally responsive science, Goethean science may serve as a kind of cultural therapeutics, a project which is necessarily interdisciplinary since it requires the integration of multiple ways of seeing from the natural sciences, the human sciences, and the humanities. (shrink)