The use of ‘race’ as a proxy for population structure in the genetic mapping of complex traits has provoked controversy about its legitimacy as a category for biomedical research, given its social and political connotations. The controversy has reignited debates among scientists and philosophers of science about whether there is a legitimate biological concept of race. This paper examines the genetic race concept as it developed historically in the work of Theodosius Dobzhansky from the 1930s to 1950s. Dobzhansky’s definitions of (...) race changed over this time from races as ‘arrays of forms’ or ‘clusters’ in 1933–1939, to races as genetically distinct geographical populations in 1940–1946, to races as genetically distinct ‘Mendelian populations’ in 1947–1955. Dobzhansky responded to nominalist challenges by appealing to the biological reality of race as a process. This response came into tension with the object ontology of race that was implied by Dobzhansky’s increasingly holistic treatment of Mendelian populations, a tension, the paper argues, he failed to appreciate or resolve. (shrink)

Essentialism--understood as the doctrine that there are natural kinds--can be sustained with respect to the most fundamental physical entities of the world, as I elsewhere argue. In this paper I take up the question of the existence of natural kinds among complex structures built out of these elementary ones. I consider a number of objections to essentialism, in particular Locke's puzzle about the existence of borderline cases. A number of recent attempts to justify biological taxonomy are critically examined. I conclude (...) that theory partially justifies such taxonomies but supports only a weaker form of essentialism. (shrink)