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  1. Eight Strategies to Engineer Acceptance of Human Germline Modifications.Shoaib Khan & Katherine Drabiak - 2024 - Journal of Bioethical Inquiry 21 (1):81-94.
    Until recently, scientific consensus held firm that genetically manipulated embryos created through methods including Mitochondrial Replacement Therapy or human germline genome editing should not be used to initiate a pregnancy. In countries that have relevant laws pertaining to heritable human germline modifications, the vast majority prohibit or restrict this practice. In the last several years, scholars have observed a transformation of scientific and policy restrictions with insistent calls for creating a regulatory pathway. Multiple stakeholders highlight the role of social consensus (...)
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  • Initial heritable genome editing: mapping a responsible pathway from basic research to the clinic.Robert Ranisch, Katharina Trettenbach & Gardar Arnason - 2023 - Medicine, Health Care and Philosophy 26 (1):21-35.
    Following the Second Summit on Human Gene Editing in Hong Kong in 2018, where the birth of two girls with germline genome editing was revealed, the need for a responsible pathway to the clinical application of human germline genome editing has been repeatedly emphasised. This paper aims to contribute to the ongoing discussion on research ethics issues in germline genome editing by exploring key issues related to the initial applications of CRISPR in reproductive medicine. Following an overview of the current (...)
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