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  1. Genealogical obscurement: mitochondrial replacement techniques and genealogical research.César Palacios-González - forthcoming - Journal of Medical Ethics.
    Mitochondrial replacement techniques (MRTs) are a new group of biotechnologies that aim to aid women whose eggs have disease-causing deleteriously mutated mitochondria to have genetically related healthy children. These techniques have also been used to aid women with poor oocyte quality and poor embryonic development, to have genetically related children. Remarkably, MRTs create humans with DNA from three sources: nuclear DNA from the intending mother and father, and mitochondrial DNA from the egg donor. In a recent publication Françoise Baylis argued (...)
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  • Should Long-Term Follow-up Post-Mitochondrial Replacement be Left up to Physicians, Parents, or Offspring?Tetsuya Ishii - 2019 - The New Bioethics 25 (4):318-331.
    UK law permits parents to use mitochondrial replacement to have genetically-related children without serious mitochondrial disease. However, long-term follow-up is required for each case. Whet...
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  • Ethical Framework for Next-Generation Genome and Epigenome Editing.Kyoko Akatsuka, Mitsuru Sasaki-Honda & Tsutomu Sawai - 2020 - American Journal of Bioethics 20 (8):32-36.
    Volume 20, Issue 8, August 2020, Page 32-36.
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  • Initial heritable genome editing: mapping a responsible pathway from basic research to the clinic.Robert Ranisch, Katharina Trettenbach & Gardar Arnason - 2023 - Medicine, Health Care and Philosophy 26 (1):21-35.
    Following the Second Summit on Human Gene Editing in Hong Kong in 2018, where the birth of two girls with germline genome editing was revealed, the need for a responsible pathway to the clinical application of human germline genome editing has been repeatedly emphasised. This paper aims to contribute to the ongoing discussion on research ethics issues in germline genome editing by exploring key issues related to the initial applications of CRISPR in reproductive medicine. Following an overview of the current (...)
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