Luciano Floridi’s informational structural realism takes a constructionist attitude towards the problems of epistemology and metaphysics, but the question of the nature of the semantical component of his view remains vexing. In this paper, I propose to dispense with the semantical component of ISR completely. I outline a Syntactical version of ISR. The unified entropy-based framework of information has been adopted as the groundwork of SISR. To establish its realist component, SISR should be able to dissolve the latching problem. We (...) have to be able to account for the informational structures–reality relationship in the absence of the standard semantical resources. The paper offers a pragmatic solution to the latching problem. I also take pains to account for the naturalistic plausibility of this solution by grounding it in the recent computational neuroscience of the predictive coding and the free energy principle. (shrink)