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  1. A relational-constructionist account of protein macrostructure and function.Gil Santos, Gabriel Vallejos & Davide Vecchi - 2020 - Foundations of Chemistry 22 (3):363-382.
    One of the foundational problems of biochemistry concerns the conceptualisation of the relationship between the composition, structure and function of macromolecules like proteins. Part of the recent philosophical literature displays a reductionist bias, that is, the endorsement of a form of microstructuralism mirroring an out-dated biochemical conceptualisation. We shall argue that such microstructuralist approaches are ultimately committed to a potentialist form of micro-predeterminism whereby the macrostructure and function of proteins is accounted for solely in terms of the intrinsic properties and (...)
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  • Multiple Routes to Animal Consciousness: Constrained Multiple Realizability Rather Than Modest Identity Theory.Jon Mallatt & Todd E. Feinberg - 2021 - Frontiers in Psychology 12.
    The multiple realizability thesis is an important philosophical and psychological concept. It says any mental state can be constructed by multiple realizability, meaning in many distinct ways from different physical parts. The goal of our study is to find if the MRT applies to the mental state of consciousness among animals. Many things have been written about MRT but the ones most applicable to animal consciousness are by Shapiro in a 2004 book called The Mind Incarnate and by Polger and (...)
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  • The emergence of the postgenomic gene.Francesca Bellazzi - 2022 - European Journal for Philosophy of Science 12 (1):1-21.
    The identity and the existence of genes has been challenged by postgenomic discoveries. Specifically, the consideration of molecular and cellular phenomena in which genes are embedded has proved relevant for their understanding. In response to these challenges, I will argue that the complexity of genetic phenomena supports the weak emergence of genes from the DNA. In Section 2, I will expose what genes are taken to be in the postgenomic world. In Section 3, I will present the relevant account of (...)
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  • ¿Es posible una ontología procesual de las entidades bioquímicas? Consideraciones a partir del caso de los receptores celulares y la señalización celular.Fiorela Alassia - 2022 - Estudios de Filosofía (Universidad de Antioquia) 65:153-175.
    Biological macromolecules, considered as the items of the biochemical domain, are typically conceived under the ontological category of substantial individuals. In this paper, I will argue that the philosophical framework of process ontology, according to which the living world is not populated by individuals but by a dynamic hierarchy of processes, is more adequate to account for the structure and functioning of macromolecules. In particular, I will analyze its application to the phenomenon of cell signaling and to one of its (...)
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  • A process ontology approach in biochemistry: the case of GPCRs and biosignaling.Fiorela Alassia - 2022 - Foundations of Chemistry 24 (3):405-422.
    According to process ontology in the philosophy of biology, the living world is better understood as processes rather than as substantial individuals. Within this perspective, an organism does not consist of a hierarchy of structures like a machine, but rather a dynamic hierarchy of processes, dynamically maintained and stabilized at different time scales. With this respect, two processual approaches on enzymes by Stein :5–22, 2004, Process Stud 34:62–80, 2005, Found Chem 8:3–29, 2006) and by Guttinger allows to think of macromolecules (...)
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  • Unity of Science.Tuomas E. Tahko - 2021 - Cambridge: Cambridge University Press.
    Unity of science was once a very popular idea among both philosophers and scientists. But it has fallen out of fashion, largely because of its association with reductionism and the challenge from multiple realisation. Pluralism and the disunity of science are the new norm, and higher-level natural kinds and special science laws are considered to have an important role in scientific practice. What kind of reductionism does multiple realisability challenge? What does it take to reduce one phenomenon to another? How (...)
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  • Multiple Realizability.John Bickle - 2008 - Stanford Encyclopedia of Philosophy.
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  • Emerging Into the Rainforest: Emergence and Special Science Ontology.Alexander Franklin & Katie Robertson - unknown
    Many philosophers of science are ontologically committed to a lush rainforest of special science entities ), but are often reticent about the criteria that determine which entities count as real. On the other hand, the metaphysics literature is much more forthcoming about such criteria, but often links ontological commitment to irreducibility. We argue that the irreducibility criteria are in tension with scientific realism: for example, they would exclude viruses, which are plausibly theoretically reducible and yet play a sufficiently important role (...)
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