In this paper we consider some of the basic elements of virtue ethics in confrontation with selected ideas of representatives of trans- and post-humanism. Their ideas challenge us to re-justify and defend the uniqueness of man (the person) as a moral subject in his complex relational physical-psycho-spiritual unity. Using this holistic moral-anthropological vision, it is possible to justify the uniqueness of the human act as moral; the nature and significance of virtue as a moral disposition for a truly good and (...) happy life; the nature and significance of happiness as a true complex eudaimonia in the dynamics of human development. In this complex process, technical artefacts and technologies help man to act in a truly human way towards himself and others, if he uses them rightly. (shrink)