If the problem of the origin of life is conceptualized as a process of emergence of biochemistry from proto-biochemistry, which in turn emerged from the organic chemistry and geochemistry of primitive earth, then the resources of the new sciences of complex systems dynamics can provide a more robust conceptual framework within which to explore the possible pathways of chemical complexification leading to living systems and biosemiosis. In such a view the emergence of life, and concomitantly of natural selection and biosemiosis, (...) is the result of deep natural laws (the outlines of which we are only beginning to perceive) and reflects a degree of holism in those systems that led to life. Further, such an approach may lead to the development of a more general theory of biology and of natural organization, one informed by semiotic concepts. (shrink)

Natural selection of specific protobiomonomers during abiogenic development of the prototype genetic code is hindered by the diversity of structural, spatial, and rotational isomers that have identical elemental composition and molecular mass (M), but can vary significantly in their physicochemical characteristics, such as the melting temperature Tm, the Tm:M ratio, and the solubility in water, due to different positions of atoms in the molecule. These parameters differ between cis- and trans-isomers of dicarboxylic acids, spatial monosaccharide isomers, and structural isomers of (...) α-, β-, and γ-amino acids. The stable planar heterocyclic molecules of the major nucleobases comprise four (C, H, N, O) or three (C, H, N) elements and contain a single –C=C bond and two nitrogen atoms in each heterocycle involved in C–N and C=N bonds. They exist as isomeric resonance hybrids of single and double bonds and as a mixture of tautomer forms due to the presence of –C=O and/or –NH2 side groups. They are thermostable, insoluble in water, and exhibit solid-state stability, which is of central importance for DNA molecules as carriers of genetic information. In M–Tm diagrams, proteinogenic amino acids and the corresponding codons are distributed fairly regularly relative to the distinct clusters of purine and pyrimidine bases, reflecting the correspondence between codons and amino acids that was established in different periods of genetic code development. The body of data on the evolution of the genetic code system indicates that the elemental composition and molecular structure of protobiomonomers, and their M, Tm, photostability, and aqueous solubility determined their selection in the emergence of the standard genetic code. (shrink)

Shamans of the Piaroa ethnic group (southern Venezuela) conceive of power in terms of knowledge derived from visionary experiences. Märipa is an epistemology concerning the translation of knowledge derived from the integrative mode of consciousness, induced primarily through the consumption of plant hallucinogens, to practical effect during waking life. I integrate mythological, neurobiological, experiential, and ethnographic data to demonstrate what märipa is, and how it functions. The theory and method of märipa underlie not only Piaroa shamanic activity, but all aspects (...) of Piaroa life; mythology, causality, eschatology, and history. Piaroa shamanic practices involve conditioning the mind to achieve optimal perceptual capacities that facilitate accurate prediction and successful psycho‐social prescription. Piaroa shamans describe their technologies of consciousness in terms of gods and spirits, but also in terms of studying and the acquisition of information. Because neurobiological processes underlie the development and experience of märipa, the language of neurobiology enables a partial translation of this indigenous epistemology. The concepts of feed forward neural processing and somatic markers are central to the processes of mental imagery cultivation that Piaroa shamans employ to divine solutions to adaptive problems. Piaroa 'techniques of ecstasy' involve the ability to apply mythological templates of human adaptation to schemas of human behaviour based on years of social analysis in association with heightened information processing capacities derivative of refined experimentation with the integrative mode of consciousness. Keyordsshamanism, neurophenomenology inugrativeconsciousness, hallucinogens. (shrink)

(1997). The evolution of consciousness as a self‐organizing information system in the society of other such systems. World Futures: Vol. 50, No. 1-4, pp. 609-616.

(1997). The topological inventions of life: From the specialization of multicellular colonies to the functioning of the vertebrate brain. World Futures: Vol. 50, No. 1-4, pp. 617-631.

Our civilization is changing and so is our science. Human beings in endeavors from education to economics need a framework for understanding which integrates the maelstrom of insights into a useable form. That, in essence, is what the study of Dynamic Evolution provides. Dynamic Evolution (also called Cosmic or General Evolution) is a synthesis of insights, ancient and cutting edge, which radically revamps our understanding of how organizations arise and how change takes place as a result of intertwined forces in (...) a co?evolving whole. What has become clear in recent years is that the two key elements in this evolutionary march are energy flow and interdependent dynamics. New understandings of how these two key features work have mushroomed in the last 30 years. Popularized under such names as chaos, complexity, self?organization theory, Gaia and the new biology, these new insights provide an increasingly clear new understanding of the world and an increasingly coherent path through the confusion of our times. This article provides a brief overview of how rules of energy?driven organization can change our picture of what we must do to build a resilient, sustainable civilization. (shrink)

(1993). The Evolution of consciousness: A theory of Historical and personal transformation. World Futures: Vol. 38, Theoretical Achievements and Practical Applications of General Evolutionary Theory, pp. 43-62.

The evolution of the biosphere has led to creation of astrophysical and telluric stable perfect system biotic regulation, which based on a high degree of closure of natural cycles. The development of human beings as bio-social, beyond the biological patterns, break these closed cycles, and dramatically broke the biotic regulation of the biosphere. As results — sustainable biosphere has become unsustainable anthroposphere. As with the origin of life physico-chemical regularities of the structure of matter turned out to be “mastered” life, (...) as soon as with the emergence of anthroposphere physical-chemicalbiological regularities of evolution are complemented by social ones. The result of the violation of natural biotic regulation broke a global environmental crisis that boomerang begins it is dangerous to human. It is theoretically possible to overcome this ecological crisis by the transition from the Neolithic paradigm of “nature conquest”, to the organization of “crisis management” of the biosphere by the activity of the society restore and “repair” the damaged processes in the biosphere. This requires a new organization in all areas of human activity, i.e., a fundamentally new paradigm of human behavior on the planet. Development within the paradigm of the Neolithic culture, leads to an increasing accumulation of non-degradable waste, determines the fatal instability of anthroposphere and, therefore, unsustainable development of civilization. It is a mistake to assume that human’s dependence on nature is reduced — it takes a different form. The forces of human as an intelligence being, “recollecting himself”, about the offense with lifesupporting bioshere’ systems, and based on the concept of controlled evolution, to assist nature to restore the disturbed natural regulations of biospheric processes. For this it need to find out what the thresholds for allowable violations of natural processes are already accomplished, and develop a plan of action for the reduction of disturbances, relying on the regenerative potential of living nature and resources of the human mind. (shrink)