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Experimentation with human subjects

Paul Abraham Freund

London,: Allen & Unwin (1972)

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The inherent paradox of clinical trials in psychiatry.H. Helmchen & B. Müller-Oerlinghausen - 1975 - Journal of Medical Ethics 1 (4):168-173.details The authors sum up the central issue of ethics in the conduct of controlled clinical trials in these two paradoxes: 'first, it is unethical to use treatment the efficacy of which has not been examined scientifically; second, it is also unethical to examine the efficacy of treatment scientifically.' In this paper they set out to demonstrate how these antithetical statements apply in controlled trials conducted in psychiatric patients. In such trials the problem of obtaining informed consent may be acute, but (...) Download Export citation Bookmark 1 citation
Composition and function of ethical committees.William W. May - 1975 - Journal of Medical Ethics 1 (1):23-29.details In this paper the need for review (ethical) committees is elaborated to include a discussion of their composition and function. In some institutions more than one such committee may be set up, a departmental ethical committee and one which studies the projects of all the departments concerned. By considering proposed research before it is started patients or volunteers are protected from injury, discomfort, and inconvenience, and the scientific validity of a clinical experiment can be scrutinized. A list of possible criteria (...) Download Export citation Bookmark 3 citations

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