Machine Learning (ML) is revolutionizing the functioning of our societies and reshaping much of the economic tissue underlying them. The deep integration of ML into the fabric of our lives has changed to way we work and communicate and how we relate to each other. In this Topical Collection we reflect on the reach and impact of this AI (ML-driven) revolution in our society, critically analyzing some of the most important ethical, epistemological, scientific, and sociological issues underlying it.