The interview is a follow-up from Samantha Frost’s article, ‘The Attentive Body’, in Body & Society 26. Tomoko Tamari invites Frost to explore her interest in ‘biocultural creatures’, with its focus on ‘bodies’ responsive self-transformation’ in epigenetic processes, and unfolds Peirce’s account of the index for understanding meaning-making in biological processes. Tamari also introduces Katherine Hayles’s notion of ‘cognitive nonconscious’ to raise the question of the possible theoretical and mechanical similarities/discrepancies between epigenetic processes in organisms and the meaning-making process in (...) computational systems. Drawing on Jacob von Uexkull’s notion of ‘umwelt’ and introducing Yoshimi Kawade’s remarks on a living being’s subjective orientation in environments, a further question about ‘intention’ and ‘subjectivity’ enables Frost to further unpack her notion of ‘the attentive self’ and discuss its relation to ‘intentionality’ and ‘referentiality’ in epigenetic processes. Finally, Samantha Frost mentions her current projects on the connection between ‘attention-as-responsive-self-transformation’ and ‘mode-of-living-as-form-of-life’. (shrink)

A quiet revolution in genetics is increasingly rendering our milieu strange and artificial. Epigenomics, informatic cousin of epigenetics, is a xenoforming process, giving birth to an alien milieu, replacing the natural with the technical. If epigenetics is understood as the heritable changes in gene expression that do not alter DNA sequence, epigenomics takes as object the set of epigenetic modifications. Environmental, social, even political aspects of life’s variability are re-understood digitally in epigenomic profiles, the previous categories computationally accounted for as (...) potential triggers of epigenesis. Following Gilbert Simondon, the xenoforming procedures of epigenomics can be understood as the concretization and adaptation processes of a technical object, the invention of which gives birth to a technogeographic milieu. In this article, the author examines Simondon’s work, especially, ‘On the Mode of Existence of Technical Objects’, alongside contemporary scholarship on epigenetics. (shrink)

Part of the normalization of assisted reproductive technologies is the premise that the children born from in vitro fertilization are no different from their counterparts conceived spontaneously. However, interest in peri-conception health and new epigenetic understandings of biological plasticity has led to some questioning the presumed irrelevance of conception in vitro, and when doing so, describing IVF children as “apparently healthy.” Taking “apparently” and “healthy” seriously, this article explores how modes of attention—ways of naming and framing embryo potentiality—shape understandings of (...) health and normality. I contend that understanding the politics of potentiality, and how they may emerge in a postgenomic age, requires an unpacking of various modes of attention and framing. Ethnographic findings from South Africa’s fertility clinics and emerging literature on epigenetic variation in IVF conception demonstrate how, under a genetic mode of attention, IVF clinics views “abnormality” as fated, unviable, and discardable. Exploring the possibility of answering the postgenomic questions to IVF reveals structural challenges to knowing long-term health implications. Incipient attempts within the fertility clinic at managing these questions shows various strategic techniques, such as leveraging epigenetics to marketable ends and shifts to individual responsibility. (shrink)