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  1. Clinical equipoise: Why still the gold standard for randomized clinical trials?Charlemagne Asonganyi Folefac & Hugh Desmond - 2024 - Clinical Ethics 19 (1):1-11.
    The principle of clinical equipoise has been variously characterized by ethicists and clinicians as fundamentally flawed, a myth, and even a moral balm. Yet, the principle continues to be treated as the de facto gold standard for conducting randomized control trials in an ethical manner. Why do we hold on to clinical equipoise, despite its shortcomings being widely known and well-advertised? This paper reviews the most important arguments criticizing clinical equipoise as well as what the most prominent proposed alternatives are. (...)
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  • A partial defense of clinical equipoise.Scott D. Gelfand - 2019 - Research Ethics 15 (2):1-17.
    In this essay, I suggest that a slightly modified version of Freedman’s formulation of the clinical equipoise requirement is justified. I begin this essay with a brief discussion of the equipoise r...
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  • What Are Our Moral Duties? Critical Reflections on Clinical Equipoise and Publication Ethics, Clinical Choices, and Moral Theory.Mark J. Cherry - 2013 - Journal of Medicine and Philosophy 38 (6):581-589.
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  • Conceptual Clarity in Clinical Bioethical Analysis.J. Clint Parker - 2020 - Journal of Medicine and Philosophy 45 (1):1-15.
    Conceptual clarity is essential when engaging in dialogue to avoid unnecessary disagreement and to promote mutual understanding. In this issue devoted to clinical bioethics, the authors exemplify the virtue of careful conceptual analysis as they explore complex clinical questions regarding the essential nature of medicine, the boundaries of killing and letting die, the meaning of irreversibility in definitions of death, the argument for a right to try experimental medications, the ethical borders in complex medical billing, and the definition and modeling (...)
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