Aristotle's explanation of what is said ‘of every’ and ‘of none’ has been interpreted either as involving individuals, or as regarding exclusively universal terms. I claim that Alexander of Aphrodisias endorsed this latter interpretation of the dictum de omni et de nullo. This interpretation affects our understanding of Alexander's syllogistic: as a matter of fact, Alexander maintained that the dictum de omni et de nullo is one of the core principles of syllogistic.