The paper is devoted to the analysis of two seminal definitions of points within the region-based framework: one by Whitehead (1929) and the other by Grzegorczyk (Synthese, 12(2-3), 228-235 1960). Relying on the work of Biacino & Gerla (Notre Dame Journal of Formal Logic, 37(3), 431-439 1996), we improve their results, solve some open problems concerning the mutual relationship between Whitehead and Grzegorczyk points, and put forward open problems for future investigation.