In nineteenth-century Britain, captive snakes in menageries and zoological gardens were routinely fed with live prey – primarily rabbits, pigeons and guinea pigs. From the late 1860s, this practice began to generate opposition on animal welfare grounds, leading to a protracted debate over its necessity, visibility and morality. Focusing on the c.1870–1914 period, when the snake-feeding controversy reached its zenith, this article charts changing attitudes towards the treatment of reptiles in captivity and asks why an apparently niche practice generated so (...) much interest. By looking at the biological arguments put forward for and against live feeding, the article traces the changing nature of humanitarian activism in the late nineteenth century and shows how the shifting character of the live-feeding debate paralleled wider trends in the animal welfare movement. It also highlights the different types of knowledge and expertise involved in the debate, as naturalists, veterinary surgeons, legal professionals, zookeepers and humanitarians offered conflicting perspectives on questions of reptilian dietary requirements and animal sentience. (shrink)