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  1. Clinical equipoise: Why still the gold standard for randomized clinical trials?Charlemagne Asonganyi Folefac & Hugh Desmond - 2024 - Clinical Ethics 19 (1):1-11.
    The principle of clinical equipoise has been variously characterized by ethicists and clinicians as fundamentally flawed, a myth, and even a moral balm. Yet, the principle continues to be treated as the de facto gold standard for conducting randomized control trials in an ethical manner. Why do we hold on to clinical equipoise, despite its shortcomings being widely known and well-advertised? This paper reviews the most important arguments criticizing clinical equipoise as well as what the most prominent proposed alternatives are. (...)
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  • Reversing “Research Exceptionalism”.Sven Ove Hansson - 2010 - American Journal of Bioethics 10 (8):66-67.
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  • Praxis relevance in science.Sven Ove Hansson - 2006 - Foundations of Science 12 (2):139-154.
    Science is praxis relevant to the extent that it guides goal-directed action by telling us how to act in order to achieve the goals. Investigations aiming at high praxis relevance are performed in various disciplines under names such as clinical trials, evaluation research, intervention research and social experiments. In this contribution, the notion of (direct) praxis relevance is delineated, and it is distinguished from related properties of science such as those of being applied and being practically useful in a wider (...)
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  • Protecting people in research: A comparison between biomedical and traffic research. [REVIEW]Sara Svensson & Sven Ove Hansson - 2007 - Science and Engineering Ethics 13 (1):99-115.
    Traffic research shares a fundamental dilemma with other areas of empirical research in which humans are potentially put at risk. Research is justified because it can improve safety in the long run. Nevertheless, people can be harmed in the research situation. Hence, we need to balance short-term risks against long-term safety improvements, much as in other areas of research with human subjects. In this paper we focus on ethical issues that arise when human beings are directly affected in the performance (...)
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  • Do we Need a Special Ethics for Research?Sven Ove Hansson - 2011 - Science and Engineering Ethics 17 (1):21-29.
    Research is subject to more stringent ethical requirements than most other human activities, and a procedure that is otherwise allowed may be forbidden in research. Hence, risk-taking is more restricted in scientific research than in most non-research contexts, and privacy is better protected in scientific questionnaires than in marketing surveys. Potential arguments for this difference are scrutinized. The case in its favour appears to be weak. A stronger case can be made in favour of a difference in the opposite direction: (...)
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  • Three Worries About Three Arguments for Research Exceptionalism.Stephen John - 2010 - American Journal of Bioethics 10 (8):67-69.
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  • Hypothetical Retrospection.Sven Ove Hansson - 2007 - Ethical Theory and Moral Practice 10 (2):145-157.
    Moral theory has mostly focused on idealized situations in which the morally relevant properties of human actions can be known beforehand. Here, a framework is proposed that is intended to sharpen moral intuitions and improve moral argumentation in problems involving risk and uncertainty. Guidelines are proposed for a systematic search of suitable future viewpoints for hypothetical retrospection. In hypothetical retrospection, a decision is evaluated under the assumption that one of the branches of possible future developments has materialized. This evaluation is (...)
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  • Ongoing processes of managing consent: the empirical ethics of using video-recording in clinical practice and research.Michelle O'Reilly, Nicola Parker & Ian Hutchby - 2011 - Clinical Ethics 6 (4):179-185.
    Using video to facilitate data collection has become increasingly common in health research. Using video in research, however, does raise additional ethical concerns. In this paper we utilize family therapy data to provide empirical evidence of how recording equipment is treated. We show that families made a distinction between what was observed through the video by the reflecting team and what was being recorded onto videotape. We show that all parties actively negotiated what should and should not go ‘on the (...)
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